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ESPEN guideline on clinical nutrition in acute and chronic pancreatitis


Marianna Arvanitakis

Johann Ockenga

Mihailo Bezmarevic

Luca Gianotti


Professor of Gastrointestinal Surgery


Christian Madl

Remy Meier

Mary Phillips


Jeanin Van Hooft

Stephan Bischoff


Both acute and chronic pancreatitis are frequent diseases of the pancreas, which, despite being of benign nature, are related to a significant risk of malnutrition and may require nutritional support. Acute necrotizing pancreatitis is encountered in 20% of patients with acute pancreatitis, is associated with increased morbidity and mortality, and may require artificial nutrition by enteral or parenteral route, as well as additional endoscopic, radiological or surgical interventions. Chronic pancreatitis represents a chronic inflammation of the pancreatic gland with development of fibrosis. Abdominal pain leading to decreased oral intake, as well as exocrine and endocrine failure are frequent complications of the disease. All of the above represent risk factors related to malnutrition. Therefore, patients with chronic pancreatitis should be considered at risk, screened and supplemented accordingly. Moreover, osteoporosis and increased facture risk should be acknowledged in patients with chronic pancreatitis, and preventive measures should be considered.


Arvanitakis, M., Ockenga, J., Bezmarevic, M., Gianotti, L., Krznarić, Ž., Lobo, D. N., …Bischoff, S. (2020). ESPEN guideline on clinical nutrition in acute and chronic pancreatitis. Clinical Nutrition, 39(3), 612-631.

Journal Article Type Article
Acceptance Date Jan 8, 2020
Online Publication Date Jan 22, 2020
Publication Date 2020-03
Deposit Date Jan 9, 2020
Publicly Available Date Jan 23, 2021
Journal Clinical Nutrition
Print ISSN 0261-5614
Publisher Elsevier
Peer Reviewed Peer Reviewed
Volume 39
Issue 3
Pages 612-631
Keywords Nutrition and Dietetics; Critical Care and Intensive Care Medicine
Public URL
Publisher URL
Additional Information This article is maintained by: Elsevier; Article Title: ESPEN guideline on clinical nutrition in acute and chronic pancreatitis; Journal Title: Clinical Nutrition; CrossRef DOI link to publisher maintained version:; Content Type: article; Copyright: © 2020 Elsevier Ltd and European Society for Clinical Nutrition and Metabolism. All rights reserved.


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