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In Situ Sulfidation of Pd/C: A Straightforward Method for Chemoselective Conjugate Reduction by Continuous Hydrogenation

Moore, Jonathan C.; Howie, Rowena A.; Bourne, Samuel L.; Jenkins, Gareth N.; Licence, Peter; Poliakoff, Martyn; George, Michael W.

Authors

Jonathan C. Moore

Rowena A. Howie

Samuel L. Bourne

Gareth N. Jenkins

Peter Licence

Martyn Poliakoff

Michael W. George



Abstract

A method has been developed for the in situ sulfidation of Pd/C under continuous flow. The approach provides a cheap, sustainable, and operationally convenient method for chemoselective conjugate reduction by continuous hydrogenation. High conversions and excellent selectivities were obtained for olefin reduction in α/β-unsaturated carbonyl compounds in the presence of hydrogenatively sensitive functionalities. The methodology was analyzed with a green metric system to highlight the sustainability features of the process.

Journal Article Type Article
Publication Date Oct 7, 2019
Journal ACS Sustainable Chemistry & Engineering
Electronic ISSN 2168-0485
Publisher American Chemical Society
Peer Reviewed Peer Reviewed
Volume 7
Issue 19
Pages 16814-16819
APA6 Citation Moore, J. C., Howie, R. A., Bourne, S. L., Jenkins, G. N., Licence, P., Poliakoff, M., & George, M. W. (2019). In Situ Sulfidation of Pd/C: A Straightforward Method for Chemoselective Conjugate Reduction by Continuous Hydrogenation. ACS Sustainable Chemistry and Engineering, 7(19), 16814-16819. https://doi.org/10.1021/acssuschemeng.9b04347
DOI https://doi.org/10.1021/acssuschemeng.9b04347
Publisher URL https://pubs.acs.org/doi/10.1021/acssuschemeng.9b04347
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