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Graphene- and Graphene Oxide-Based Nanocomposite Platforms for Electrochemical Biosensing Applications

Thangamuthu, Madasamy; Hsieh, Kuan Yu; Kumar, Priyank V.; Chen, Guan-Yu

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Authors

Kuan Yu Hsieh

Priyank V. Kumar

Guan-Yu Chen



Abstract

Graphene and its derivatives such as graphene oxide (GO) and reduced GO (rGO) offer excellent electrical, mechanical and electrochemical properties. Further, due to the presence of high surface area, and a rich oxygen and defect framework, they are able to form nanocomposites with metal/semiconductor nanoparticles, metal oxides, quantum dots and polymers. Such nanocomposites are becoming increasingly useful as electrochemical biosensing platforms. In this review, we present a brief introduction on the aforementioned graphene derivatives, and discuss their synthetic strategies and structure–property relationships important for biosensing. We then highlight different nanocomposite platforms that have been developed for electrochemical biosensing, introducing enzymatic biosensors, followed by non-enzymatic biosensors and immunosensors. Additionally, we briefly discuss their role in the emerging field of biomedical cell capture. Finally, a brief outlook on these topics is presented.

Citation

Thangamuthu, M., Hsieh, K. Y., Kumar, P. V., & Chen, G.-Y. (2019). Graphene- and Graphene Oxide-Based Nanocomposite Platforms for Electrochemical Biosensing Applications. International Journal of Molecular Sciences, 20(12), Article 2975. https://doi.org/10.3390/ijms20122975

Journal Article Type Article
Acceptance Date Jun 4, 2019
Online Publication Date Jun 18, 2019
Publication Date Jun 2, 2019
Deposit Date Aug 1, 2023
Publicly Available Date Aug 2, 2023
Journal International Journal of Molecular Sciences
Print ISSN 1661-6596
Publisher MDPI
Peer Reviewed Peer Reviewed
Volume 20
Issue 12
Article Number 2975
DOI https://doi.org/10.3390/ijms20122975
Keywords graphene; graphene oxide; reduced graphene oxide; electrochemical biosensor; cell capture
Public URL https://nottingham-repository.worktribe.com/output/23005624
Publisher URL https://www.mdpi.com/1422-0067/20/12/2975

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