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Quantitative assessment of sitting time in ambulant adults with Muscular Dystrophy

Jacques, Matthew F.; Onambele-Pearson, Gladys L.; Edwards, Bryn; De Goede, Christian G.; Morse, Christopher I.


Gladys L. Onambele-Pearson

Bryn Edwards

Christian G. De Goede

Christopher I. Morse


Julie Dumonceaux


Current investigations into physical behaviour in Muscular Dystrophy (MD) have focussed largely on physical activity (PA). Negative health behaviours such as sedentary behaviour (Physical Behaviour) and sitting time (Posture Classification) are widely recognised to negatively influence health, but by contrast are poorly reported, yet could be easier behaviours to modify.

14 ambulant men with MD and 12 healthy controls (CTRL) subjects completed 7-days of free-living with wrist-worn accelerometry, assessing physical behaviour (SB or PA) and Posture Classification (Sitting or Standing), presented at absolute (minutes) or relative (% Waking Hours). Participant body composition (Fat Mass and Fat Free Mass) were assessed by Bioelectrical Impedance, while functional status was assessed by 10 m walk test and a functional scale (Swinyard Scale).

Absolute Sedentary Behaviour (2.2 Hours, p = 0.025) and Sitting Time (1.9 Hours, p = 0.030 was greater in adults with MD compared to CTRL and Absolute Physical Activity (3.4 Hours, p < 0.001) and Standing Time (3.2 Hours, p < 0.001) was lower in adults with MD compared to CTRL. Absolute hours of SB was associated with Fat Mass (Kg) (R = 0.643, p < 0.05) in ambulatory adults with MD,

This study has demonstrated increased Sedentary Behaviour (2.2 hours) and Sitting time (1.9 Hours) in adults with MD compared to healthy controls. Extended waking hours in sitting and SB raises concerns with regards to progression of potential cardio-metabolic diseases and co-morbidities in MD.


Jacques, M. F., Onambele-Pearson, G. L., Edwards, B., De Goede, C. G., & Morse, C. I. (2021). Quantitative assessment of sitting time in ambulant adults with Muscular Dystrophy. PLoS ONE, 16(11), Article e0260491.

Journal Article Type Article
Acceptance Date Nov 10, 2021
Online Publication Date Nov 19, 2021
Publication Date 2021
Deposit Date Nov 26, 2022
Publicly Available Date Dec 2, 2022
Journal PLoS ONE
Electronic ISSN 1932-6203
Publisher Public Library of Science
Peer Reviewed Peer Reviewed
Volume 16
Issue 11
Article Number e0260491
Keywords Multidisciplinary
Public URL
Publisher URL


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