N. A. Quraishi
Does surgical site infection influence neurological outcome and survival in patients undergoing surgery for metastatic spinal cord compression?
Quraishi, N. A.; Ahmed, M. S.; Arealis, G.; Boszczyk, B. M.; Edwards, K. L.
M. S. Ahmed
B. M. Boszczyk
KIMBERLEY EDWARDS Kimberley.Edwards@nottingham.ac.uk
Professor of Sport, exercise and Nutrition Education
Purpose: Most of the literature on infection after surgery for spinal metastases focuses on incidence and risk factors for surgical site infection (SSI). To the best of our knowledge, there is no report on the influence of infection on neurological outcome and survival in patients undergoing emergent surgery for metastatic spinal cord compression (MSCC).
Methods: Our aim was to establish if SSIs adversely affected the neurological outcome and survival in patients with MSCC. We reviewed 318 consecutive patients admitted for surgical intervention for MSCC from October 2005 to October 2012. Morbidity (neurological outcome, length of hospital stay and additional procedures) and survival rates were analysed.
Results: During this study period, the incidence of infection was 29/318 (9.1%). The median length of stay in hospital in the infected group was 25 days compared to 13 days in the non-infected group (p = 0.001). Twenty out of the 29 (69%) infected patients underwent an additional procedure (29 procedures in total) compared to 9/289 (3%) non-infected patients (p = 0.001). There was no statistical difference between the two groups with regard to neurological outcome (p = 0.37) but the survival rate was statistically different between the two groups [infected group: median survival 131 days (19–1558) vs. non-infected group: 258 days (5–2696; p = 0.03)].
Conclusion: Surgical site infection increased the morbidity with considerably longer hospital stay and requirement for additional
procedures. Although there was no difference in neurological outcome, the infected group of patients had a significantly
Quraishi, N. A., Ahmed, M. S., Arealis, G., Boszczyk, B. M., & Edwards, K. L. (2018). Does surgical site infection influence neurological outcome and survival in patients undergoing surgery for metastatic spinal cord compression?. European Spine Journal, doi:10.1007/s00586-018-5797-4
|Journal Article Type||Article|
|Acceptance Date||Oct 14, 2018|
|Online Publication Date||Oct 27, 2018|
|Publication Date||Oct 27, 2018|
|Deposit Date||Oct 31, 2018|
|Publicly Available Date||Oct 31, 2018|
|Journal||European Spine Journal|
|Peer Reviewed||Peer Reviewed|
|Keywords||Surgery; Orthopedics and Sports Medicine|
Does surgical site infection influence neurological outcome
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