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The mechanical property, degradation and cytocompatibility analysis of novel phosphate glass fiber textiles

Zhu, Chenkai; Ahmed, Ifty; Parsons, Andrew; Liu, Jinsong; Liu, Xiaoling

Authors

Chenkai Zhu

Jinsong Liu

Xiaoling Liu



Abstract

Phosphate glass fibres have been widely considered as potential biomedical materials for the orthopedical application due to full degradability and excellent cytocompatibility. In this study, phosphate based glass fibres were drawn from the glass system 48P2O5-12B2O3-14CaO-20MgO-1Na2O-5Fe2O3, via a melt-drawn spinning process and then woven into textile fabric using a small lab-scale inkle loom. The annealing treatment was applied to both fibres and textiles with 1-hour heat treatment at 540 °C, which was 10 °C above glass transition temperature. An increase in Young’s modulus was observed for the single filament fibres and a decrease in tensile strength with annealing treatment. During the degradation period, the tensile strength of non-annealed fibres (N-fibre) presented a decrease by day 28, whilst annealed fibres (A-fibre) had increased by day 7, then decreased by day 28, which was suggested to be due to the peeling effect observed on the surface of the fibres. The cytocompatibility of the textile fabric with annealing treatment (A-textile) and non-annealed (N-textile) was characterised via seeding of MG63 cells. Higher metabolic activity and DNA concentration were obtained for the A-textile samples when compared to N-textile, which was suggested to be due to the lower dissolution rate of the A-textile resulting in fewer ions leached into the solution. The phosphate glass fibre textiles investigated in this study have shown potential application as bioresorbable composites reinforcement for orthopaedic treatment.

Citation

Zhu, C., Ahmed, I., Parsons, A., Liu, J., & Liu, X. (2018). The mechanical property, degradation and cytocompatibility analysis of novel phosphate glass fiber textiles. Textile Research Journal, 89(16), doi:10.1177/0040517518809052

Journal Article Type Article
Acceptance Date Sep 27, 2018
Online Publication Date Nov 6, 2018
Publication Date Nov 6, 2018
Deposit Date Oct 10, 2018
Publicly Available Date Oct 10, 2018
Journal Textile Research Journal
Print ISSN 0040-5175
Electronic ISSN 1746-7748
Publisher SAGE Publications
Peer Reviewed Peer Reviewed
Volume 89
Issue 16
DOI https://doi.org/10.1177/0040517518809052
Public URL https://nottingham-repository.worktribe.com/output/1156744
Publisher URL https://journals.sagepub.com/doi/full/10.1177/0040517518809052

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