The mechanical property, degradation and cytocompatibility analysis of novel phosphate glass fiber textiles
Zhu, Chenkai; Ahmed, Ifty; Parsons, Andrew; Liu, Jinsong; Liu, Xiaoling
Associate Professor IFTY AHMED firstname.lastname@example.org
ANDREW PARSONS ANDREW.PARSONS@NOTTINGHAM.AC.UK
Senior Research Fellow
Phosphate glass fibres have been widely considered as potential biomedical materials for the orthopedical application due to full degradability and excellent cytocompatibility. In this study, phosphate based glass fibres were drawn from the glass system 48P2O5-12B2O3-14CaO-20MgO-1Na2O-5Fe2O3, via a melt-drawn spinning process and then woven into textile fabric using a small lab-scale inkle loom. The annealing treatment was applied to both fibres and textiles with 1-hour heat treatment at 540 °C, which was 10 °C above glass transition temperature. An increase in Young’s modulus was observed for the single filament fibres and a decrease in tensile strength with annealing treatment. During the degradation period, the tensile strength of non-annealed fibres (N-fibre) presented a decrease by day 28, whilst annealed fibres (A-fibre) had increased by day 7, then decreased by day 28, which was suggested to be due to the peeling effect observed on the surface of the fibres. The cytocompatibility of the textile fabric with annealing treatment (A-textile) and non-annealed (N-textile) was characterised via seeding of MG63 cells. Higher metabolic activity and DNA concentration were obtained for the A-textile samples when compared to N-textile, which was suggested to be due to the lower dissolution rate of the A-textile resulting in fewer ions leached into the solution. The phosphate glass fibre textiles investigated in this study have shown potential application as bioresorbable composites reinforcement for orthopaedic treatment.
Zhu, C., Ahmed, I., Parsons, A., Liu, J., & Liu, X. (2018). The mechanical property, degradation and cytocompatibility analysis of novel phosphate glass fiber textiles. Textile Research Journal, 89(16), doi:10.1177/0040517518809052
|Journal Article Type||Article|
|Acceptance Date||Sep 27, 2018|
|Online Publication Date||Nov 6, 2018|
|Publication Date||Nov 6, 2018|
|Deposit Date||Oct 10, 2018|
|Publicly Available Date||Oct 10, 2018|
|Journal||Textile Research Journal|
|Peer Reviewed||Peer Reviewed|
The Mechanical Property Degradation And Cytocompatibility Analysis Of N..