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Association of Pretransplant Renal Function With Liver Graft and Patient Survival After Liver Transplantation in Patients With Nonalcoholic Steatohepatitis

Molnar, Miklos Z.; Joglekar, Kiran; Jiang, Yu; Cholankeril, George; Abdul, Mubeen Khan Mohammed; Kedia, Satish; Gonzalez, Humberto C.; Ahmed, Aijaz; Singal, Ashwani; Bhamidimarri, Kalyan Ram; Aithal, Guruprasad Padur; Duseja, Ajay; Wong, Vincent Wai-Sun; Gulnare, Agayeva; Puri, Puneet; Nair, Sathees; Eason, James D.; Satapathy, Sanjaya K.

Association of Pretransplant Renal Function With Liver Graft and Patient Survival After Liver Transplantation in Patients With Nonalcoholic Steatohepatitis Thumbnail


Authors

Miklos Z. Molnar

Kiran Joglekar

Yu Jiang

George Cholankeril

Mubeen Khan Mohammed Abdul

Satish Kedia

Humberto C. Gonzalez

Aijaz Ahmed

Ashwani Singal

Kalyan Ram Bhamidimarri

Ajay Duseja

Vincent Wai-Sun Wong

Agayeva Gulnare

Puneet Puri

Sathees Nair

James D. Eason

Sanjaya K. Satapathy



Abstract

Background: Nonalcoholic Steatohepatitis(NASH) is one of the top three indications for liver transplantation in western countries. It is unknown whether renal dysfunction at the time of liver transplantation has any effect on post-liver transplantation outcomes in recipients with NASH.
Methods: From the United Network for Organ Sharing-Standard Transplant Analysis and Research(UNOS-STAR) dataset, we identified 4,088 NASH recipients who received deceased donor liver transplant. We divided our recipients a priori into three categories: Group I with estimated glomerular filtration rate (eGFR)

Citation

Molnar, M. Z., Joglekar, K., Jiang, Y., Cholankeril, G., Abdul, M. K. M., Kedia, S., …Satapathy, S. K. (2019). Association of Pretransplant Renal Function With Liver Graft and Patient Survival After Liver Transplantation in Patients With Nonalcoholic Steatohepatitis. Liver Transplantation, 25(3), 399-410. https://doi.org/10.1002/lt.25367

Journal Article Type Article
Acceptance Date Sep 30, 2018
Online Publication Date Oct 28, 2018
Publication Date Mar 1, 2019
Deposit Date Oct 2, 2018
Publicly Available Date Oct 29, 2019
Journal Liver Transplantation
Print ISSN 1527-6465
Electronic ISSN 1527-6473
Publisher Wiley
Peer Reviewed Peer Reviewed
Volume 25
Issue 3
Pages 399-410
DOI https://doi.org/10.1002/lt.25367
Keywords Nonalcoholic steatohepatitis, liver transplantation, graft loss, mortality, renal function
Public URL https://nottingham-repository.worktribe.com/output/1141868
Publisher URL https://aasldpubs.onlinelibrary.wiley.com/doi/abs/10.1002/lt.25367

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