Association of Pretransplant Renal Function With Liver Graft and Patient Survival After Liver Transplantation in Patients With Nonalcoholic Steatohepatitis

Molnar, Miklos Z.; Joglekar, Kiran; Jiang, Yu; Cholankeril, George; Abdul, Mubeen Khan Mohammed; Kedia, Satish; Gonzalez, Humberto C.; Ahmed, Aijaz; Singal, Ashwani; Bhamidimarri, Kalyan Ram; Aithal, Guruprasad Padur; Duseja, Ajay; Wong, Vincent Wai-Sun; Gulnare, Agayeva; Puri, Puneet; Nair, Sathees; Eason, James D.; Satapathy, Sanjaya K.

Abstract

Background: Nonalcoholic Steatohepatitis(NASH) is one of the top three indications for liver transplantation in western countries. It is unknown whether renal dysfunction at the time of liver transplantation has any effect on post-liver transplantation outcomes in recipients with NASH.
Methods: From the United Network for Organ Sharing-Standard Transplant Analysis and Research(UNOS-STAR) dataset, we identified 4,088 NASH recipients who received deceased donor liver transplant. We divided our recipients a priori into three categories: Group I with estimated glomerular filtration rate (eGFR)

Citation

Molnar, M. Z., Joglekar, K., Jiang, Y., Cholankeril, G., Abdul, M. K. M., Kedia, S., …Satapathy, S. K. (2019). Association of Pretransplant Renal Function With Liver Graft and Patient Survival After Liver Transplantation in Patients With Nonalcoholic Steatohepatitis. Liver Transplantation, 25(3), 399-410. https://doi.org/10.1002/lt.25367

• Journal Article Type: Article
• Acceptance Date: Sep 30, 2018
• Online Publication Date: Oct 28, 2018
• Publication Date: Mar 1, 2019
• Deposit Date: Oct 2, 2018
• Publicly Available Date: Oct 29, 2019
• Journal: Liver Transplantation
• Print ISSN: 1527-6465
• Electronic ISSN: 1527-6473
• Publisher: Wiley
• Peer Reviewed: Peer Reviewed
• Volume: 25
• Issue: 3
• Pages: 399-410
• DOI: https://doi.org/10.1002/lt.25367
• Keywords: Nonalcoholic steatohepatitis, liver transplantation, graft loss, mortality, renal function
• Public URL: https://nottingham-repository.worktribe.com/output/1141868
• Publisher URL: https://aasldpubs.onlinelibrary.wiley.com/doi/abs/10.1002/lt.25367
• Contract Date: Oct 2, 2018