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Intersection of inflammation and herbal medicine in the treatment of osteoarthritis

Mobasheri, Ali


Ali Mobasheri


Herbal remedies and dietary supplements have become an important area of research and clinical practice in orthopaedics and rheumatology. Understanding the risks and benefits of using herbal medicines in the treatment of arthritis, rheumatic diseases, and musculoskeletal complaints is a key priority of physicians and their patients. This review discusses the latest advances in the use of herbal medicines for treating osteoarthritis (OA) by focusing on the most significant trends and developments. This paper sets the scene by providing a brief introduction to ethnopharmacology, Ayurvedic medicine, and nutrigenomics before discussing the scientific and mechanistic rationale for targeting inflammatory signalling pathways in OA by use of herbal medicines. Special attention is drawn to the conceptual and practical difficulties associated with translating data from in-vitro experiments to in-vivo studies. Issues relating to the low bioavailability of active ingredients in herbal medicines are discussed, as also is the need for large-scale, randomized clinical trials


Mobasheri, A. (2012). Intersection of inflammation and herbal medicine in the treatment of osteoarthritis. Current Rheumatology Reports, 14(6),

Journal Article Type Article
Publication Date Dec 1, 2012
Deposit Date Mar 27, 2014
Publicly Available Date Mar 27, 2014
Journal Current Rheumatology Reports
Print ISSN 1523-3774
Electronic ISSN 1523-3774
Publisher Springer Verlag
Peer Reviewed Peer Reviewed
Volume 14
Issue 6
Public URL
Publisher URL


art%3A10.1007%2Fs11926-012-0288-9.pdf (350 Kb)

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