Copper(II)-mediated synthesis of indolequinones from bromoquinones and enamines

Inman, Martyn; Moody, Christopher J.

Abstract

The reaction of enamines and bromoquinones in the presence of copper(II) acetate and potassium carbonate results in a regiospecific synthesis of indolequinones. The reaction is broad in scope and scalable and provides a route to the core structure that is present in several biologically interesting natural and synthetic compounds.

Citation

Inman, M., & Moody, C. J. (2013). Copper(II)-mediated synthesis of indolequinones from bromoquinones and enamines. European Journal of Organic Chemistry, 2013(11), https://doi.org/10.1002/ejoc.201201597

• Journal Article Type: Article
• Publication Date: Apr 1, 2013
• Deposit Date: May 30, 2014
• Publicly Available Date: May 30, 2014
• Journal: European Journal of Organic Chemistry
• Print ISSN: 1434-193X
• Electronic ISSN: 1099-0690
• Publisher: Wiley
• Peer Reviewed: Peer Reviewed
• Volume: 2013
• Issue: 11
• DOI: https://doi.org/10.1002/ejoc.201201597
• Keywords: Synthetic methods, Cyclization, Nitrogen heterocycles, Quinones, Copper
• Public URL: https://nottingham-repository.worktribe.com/output/1002345
• Publisher URL: http://onlinelibrary.wiley.com/doi/10.1002/ejoc.201201597/full