Outputs (17)

Lessons from the PROTECT-CH COVID-19 platform trial in care homes (2025)
Journal Article
Bath, P. M., Ball, J., Boyd, M., Gage, H., Glover, M., Godfrey, M., Guthrie, B., Hewitt, J., Howard, R., Jaki, T., Juszczak, E., Lasserson, D., Leighton, P., Leyland, V., Shen Lim, W., Logan, P., Meakin, G., Montgomery, A., Ogollah, R., Passmore, P., …Gordon, A. L. (2025). Lessons from the PROTECT-CH COVID-19 platform trial in care homes. Health Technology Assessment, https://doi.org/10.3310/MTRS8833

Background
Coronavirus disease-2019 was associated with significant mortality and morbidity in care homes in 2020–1. Repurposed antiviral drugs might reduce morbidity and mortality through reducing viral transmission, infection, replication and infl... Read More about Lessons from the PROTECT-CH COVID-19 platform trial in care homes.

The Five Safes RO-Crate: FAIR Digital Objects for Trusted Research Environments for Health Data Research (2025)
Presentation / Conference Contribution
Soiland-Reyes, S., Wheater, S., Giles, T., Couldridge, J., Quinlan, P., & Goble, C. (2025, March). The Five Safes RO-Crate: FAIR Digital Objects for Trusted Research Environments for Health Data Research. Presented at International FAIR Digital Objects Implementation Summit 2024, Berlin

Trusted Research Environments (TREs) are secure locations in which health and other sensitive data are placed and made available for researchers to analyse under strict controls. TRE’s in the UK operate under the Five Safes governance framework of sa... Read More about The Five Safes RO-Crate: FAIR Digital Objects for Trusted Research Environments for Health Data Research.

Homogeneous catalyst graph neural network: A human-interpretable graph neural network tool for ligand optimization in asymmetric catalysis (2025)
Journal Article
Aguilar-Bejarano, E., Özcan, E., Rit, R. K., Li, H., Lam, H. W., Moore, J. C., Woodward, S., & Figueredo, G. (2025). Homogeneous catalyst graph neural network: A human-interpretable graph neural network tool for ligand optimization in asymmetric catalysis. iScience, 28(3), Article 111881. https://doi.org/10.1016/j.isci.2025.111881

Optimization of metal-ligand asymmetric catalysts is usually done by empirical trials, where the ligand is arbitrarily modified, and the new catalyst is re-evaluated in the lab. This procedure is not efficient and alternative strategies are highly de... Read More about Homogeneous catalyst graph neural network: A human-interpretable graph neural network tool for ligand optimization in asymmetric catalysis.

Data-driven shear strength prediction of RC beams strengthened with FRCM jackets using machine learning approach (2024)
Journal Article
Liu, X., Figueredo, G. P., Gordon, G. S., & Thermou, G. E. (2025). Data-driven shear strength prediction of RC beams strengthened with FRCM jackets using machine learning approach. Engineering Structures, 325, Article 119485. https://doi.org/10.1016/j.engstruct.2024.119485

Fabric Reinforced Cementitious Matrix (FRCM) is an effective intervention method for improving the shear strength of existing reinforced concrete (RC) beams, yet predictive analyses are scarce. This study introduces and compares nine machine learning... Read More about Data-driven shear strength prediction of RC beams strengthened with FRCM jackets using machine learning approach.

Monitoring university student response to social distancing policy during the SARS-CoV-2 pandemic using Bluetooth: the RADAR study (2024)
Journal Article
Bolton, K. J., Mendez-Villalon, A., Nanji, H., Jia, R., Ayling, K., Figueredo, G., & Vedhara, K. (2024). Monitoring university student response to social distancing policy during the SARS-CoV-2 pandemic using Bluetooth: the RADAR study. Mathematics in Medical and Life Sciences, 1(1), Article 2425096. https://doi.org/10.1080/29937574.2024.2425096

Aim: We use the Remote Assessment of Disease and Relapses platform (RADAR) to collect Bluetooth contact and location data from university students. We test the ability of this technology to objectively capture social interaction, explore the propensi... Read More about Monitoring university student response to social distancing policy during the SARS-CoV-2 pandemic using Bluetooth: the RADAR study.

The Challenges and Lessons Learned Building a New UK Infrastructure for Finding and Accessing Population-Wide COVID-19 Data for Research and Public Health Analysis: The CO-CONNECT Project (2024)
Journal Article
Jefferson, E., Milligan, G., Johnston, J., Mumtaz, S., Cole, C., Best, J., Giles, T. C., Cox, S., Masood, E., Horban, S., Urwin, E., Beggs, J., Chuter, A., Reilly, G., Morris, A., Seymour, D., Hopkins, S., Sheikh, A., & Quinlan, P. (2024). The Challenges and Lessons Learned Building a New UK Infrastructure for Finding and Accessing Population-Wide COVID-19 Data for Research and Public Health Analysis: The CO-CONNECT Project. Journal of Medical Internet Research, 26, Article e50235. https://doi.org/10.2196/50235

The COVID-19-Curated and Open Analysis and Research Platform (CO-CONNECT) project worked with 22 organizations across the United Kingdom to build a federated platform, enabling researchers to instantaneously and dynamically query federated datasets t... Read More about The Challenges and Lessons Learned Building a New UK Infrastructure for Finding and Accessing Population-Wide COVID-19 Data for Research and Public Health Analysis: The CO-CONNECT Project.

The association between drugs and vaccines commonly prescribed to older people and bullous pemphigoid: a case-control study (2024)
Journal Article
Swiderski, M., Vinogradova, Y., Knaggs, R. D., Harman, K., Harwood, R. H., Prasad, V., Persson, M. S. M., Figueredo, G., Layfield, C., & Gran, S. (2025). The association between drugs and vaccines commonly prescribed to older people and bullous pemphigoid: a case-control study. British Journal of Dermatology, 192(3), 440-449. https://doi.org/10.1093/bjd/ljae416

Background
Bullous pemphigoid (BP) is an autoimmune skin disease that affects mainly older people. Numerous drugs have been previously associated with BP based on case series and small hospital-based studies. More reliable and precise estimates of a... Read More about The association between drugs and vaccines commonly prescribed to older people and bullous pemphigoid: a case-control study.

Association between drugs and vaccines commonly prescribed to older people and bullous pemphigoid: a case-control study (2024)
Journal Article
Swiderski, M., Vinogradova, Y., Knaggs, R. D., Harman, K., Harwood, R. H., Prasad, V., Persson, M. S., Figueredo, G., Layfield, C., & Gran, S. (2025). Association between drugs and vaccines commonly prescribed to older people and bullous pemphigoid: a case-control study. British Journal of Dermatology, 192(3), 440-449. https://doi.org/10.1093/bjd/ljae416

Background: Bullous pemphigoid (BP) is an autoimmune skin disease that mainly affects older people. Based on case series and small hospital-based studies, a number of drugs have been associated with BP. More reliable and precise estimates of associat... Read More about Association between drugs and vaccines commonly prescribed to older people and bullous pemphigoid: a case-control study.

Association between Nutritional Status Assessed by Body Mass Index and Crohn’s Disease Phenotype: A Nation-Wide Analysis (2024)
Journal Article
Ndzo, J., Vuyyuru, S. K., Trimble, T., Yan, K., Figueredo, G., & Moran, G. W. (in press). Association between Nutritional Status Assessed by Body Mass Index and Crohn’s Disease Phenotype: A Nation-Wide Analysis. Journal of Crohn's and Colitis,

Background & Aims:

Incidence of obesity and Crohn’s disease (CD) is increasing globally. Therefore, understanding any associations between adiposity and disease phenotype is crucial. We aimed explore the relationship between nutritional status me... Read More about Association between Nutritional Status Assessed by Body Mass Index and Crohn’s Disease Phenotype: A Nation-Wide Analysis.

Utilising User Data from a Food-Sharing App to Evidence the "Heat-or-Eat" Dilemma (2024)
Presentation / Conference Contribution
Semple, T., Harvey, J., Rodrigues, L., Gillott, M., Figueredo, G., & Nica-Avram, G. (2024, May). Utilising User Data from a Food-Sharing App to Evidence the "Heat-or-Eat" Dilemma. Presented at 2nd Digital Footprints Conference: Linking Digital Data for Social Impact, Bristol, UK

Introduction & Background
Previous literature has found that financially vulnerable households often make involuntary spending trade-offs between necessities, particularly energy and food. This effect is especially pronounced during winter, when hom... Read More about Utilising User Data from a Food-Sharing App to Evidence the "Heat-or-Eat" Dilemma.