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Outputs (14)

The clinical and cost effectiveness of a STAndardised DIagnostic Assessment for children and adolescents with emotional difficulties (STADIA); multi- centre randomised controlled trial (2025)
Journal Article
Sayal, K., Wyatt, L., Partlett, C., Ewart, C., Bhardwaj, A., Dubicka, B., Marshall, T., Gledhill, J., Lang, A., Sprange, K., Thomson, L., Moody, S., Holt, G., Bould, H., Upton, C., Keane, M., Cox, E., James, M., & Montgomery, A. (in press). The clinical and cost effectiveness of a STAndardised DIagnostic Assessment for children and adolescents with emotional difficulties (STADIA); multi- centre randomised controlled trial. Journal of Child Psychology and Psychiatry, https://doi.org/10.1111/jcpp.14090

Background

Standardised Diagnostic Assessment tools, such as the Development and Well-Being Assessment (DAWBA), may aid detection and diagnosis of emotional disorders but there is limited real-world evidence of their clinical or cost effectiveness... Read More about The clinical and cost effectiveness of a STAndardised DIagnostic Assessment for children and adolescents with emotional difficulties (STADIA); multi- centre randomised controlled trial.

Arterial spin labelling perfusion MRI analysis for the Human Connectome Project Lifespan Ageing and Development studies (2025)
Journal Article
Kirk, T. F., McConnell, F. A. K., Toner, J., Craig, M. S., Carone, D., Li, X., Suzuki, Y., Coalson, T. S., Harms, M. P., Glasser, M. F., & Chappell, M. A. (2025). Arterial spin labelling perfusion MRI analysis for the Human Connectome Project Lifespan Ageing and Development studies. Imaging Neuroscience, https://doi.org/10.1162/imag_a_00444

The Human Connectome Project Lifespan studies cover the Development (5-21) and Aging (36-100+) phases of life. Arterial spin labelling (ASL) was included in the imaging protocol, resulting in one of the largest datasets collected to-date of high spat... Read More about Arterial spin labelling perfusion MRI analysis for the Human Connectome Project Lifespan Ageing and Development studies.

Recombinant Human Tissue Kallikrein-1 for Treating Acute Ischemic Stroke and Preventing Recurrence (2025)
Journal Article
Kasner, S. E., Bath, P. M., Hill, M. D., Volpi, J. J., Giuffre, M., Masuoka, L., Wambeke, D., & Madeddu, P. R. (2025). Recombinant Human Tissue Kallikrein-1 for Treating Acute Ischemic Stroke and Preventing Recurrence. Stroke, https://doi.org/10.1161/STROKEAHA.124.048858

Novel strategies are needed for the treatment of acute ischemic stroke when revascularization therapies are not clinically appropriate or are unsuccessful. Recombinant human tissue kallikrein-1 (rKLK1), a bradykinin-producing enzyme, offers a promis... Read More about Recombinant Human Tissue Kallikrein-1 for Treating Acute Ischemic Stroke and Preventing Recurrence.