Mental Health and Clinical Neurosciences

Donor Variability Alters the Characteristics of Human Brain Microvascular Endothelial Cells (2025)
Journal Article
Ya, J., & Bayraktutan, U. (in press). Donor Variability Alters the Characteristics of Human Brain Microvascular Endothelial Cells. Current Issues in Molecular Biology, 47(2), Article 73. https://doi.org/10.3390/cimb47020073

Primary brain microvascular endothelial cells (BMECs) are widely used in a large number of in vitro studies each year to better mimic their physiological characteristics in vivo. However, potential changes in primary endothelial cells stemming from d... Read More about Donor Variability Alters the Characteristics of Human Brain Microvascular Endothelial Cells.

Self-reported and task-based impulsivity, aggression, and childhood trauma in the general population: A United- Kingdom-based online survey (2025)
Journal Article
Aubrey, O., Jones, K. A., & Paddock, E. (2025). Self-reported and task-based impulsivity, aggression, and childhood trauma in the general population: A United- Kingdom-based online survey. Journal of Criminal Psychology,

Purpose
The societal, economic and personal costs of aggression are indisputable. Impulsivity and childhood trauma (CT) play a role in aggression but less is known about the potential mechanisms underlying these associations. This study aimed to inv... Read More about Self-reported and task-based impulsivity, aggression, and childhood trauma in the general population: A United- Kingdom-based online survey.

“It’s a struggle”: a qualitative investigation of relations between cancer-related fatigue and work outcomes (2025)
Journal Article
Rossiter, L., Houdmont, J., & Brooks, C. (2025). “It’s a struggle”: a qualitative investigation of relations between cancer-related fatigue and work outcomes. Disability and Rehabilitation, https://doi.org/10.1080/09638288.2025.2451213

Purpose
Cancer-related fatigue (CRF) has been associated with various adverse work outcomes in quantitative research. However, there is limited understanding regarding how and why these outcomes arise for survivors experiencing fatigue. In response,... Read More about “It’s a struggle”: a qualitative investigation of relations between cancer-related fatigue and work outcomes.

Younger adults may be faster at making semantic predictions, but older adults are more efficient (2025)
Journal Article
Fernandez, L. B., Shehzad, M., & Hadley, L. V. (2025). Younger adults may be faster at making semantic predictions, but older adults are more efficient. Psychology and Aging, https://doi.org/10.1037/pag0000872

While there is strong evidence that younger adults use contextual information to generate semantic predictions, findings from older adults are less clear. Age affects cognition in a variety of different ways that may impact prediction mechanisms; whi... Read More about Younger adults may be faster at making semantic predictions, but older adults are more efficient.

What works well for people with dementia and their supporters from South Asian, African and Caribbean communities in the UK: a narrative synthesis systematic review and expert consultations (2025)
Journal Article
Mcdermott, O., Sobers, T., Mukadam, N., Lee, A. R., & Orrell, M. (in press). What works well for people with dementia and their supporters from South Asian, African and Caribbean communities in the UK: a narrative synthesis systematic review and expert consultations. International Journal of Geriatric Psychiatry,

Objectives
This review aims to synthesise the evidence regarding the use and provision of dementia services and support for people with dementia and/or supporters from South Asian, African or Caribbean back grounds living in the UK.

Methods
A na... Read More about What works well for people with dementia and their supporters from South Asian, African and Caribbean communities in the UK: a narrative synthesis systematic review and expert consultations.

The clinical and cost effectiveness of a STAndardised DIagnostic Assessment for children and adolescents with emotional difficulties (STADIA); multi- centre randomised controlled trial (2025)
Journal Article
Sayal, K., Wyatt, L., Partlett, C., Ewart, C., Bhardwaj, A., Dubicka, B., Marshall, T., Gledhill, J., Lang, A., Sprange, K., Thomson, L., Moody, S., Holt, G., Bould, H., Upton, C., Keane, M., Cox, E., James, M., & Montgomery, A. (in press). The clinical and cost effectiveness of a STAndardised DIagnostic Assessment for children and adolescents with emotional difficulties (STADIA); multi- centre randomised controlled trial. Journal of Child Psychology and Psychiatry, https://doi.org/10.1111/jcpp.14090

Background

Standardised Diagnostic Assessment tools, such as the Development and Well-Being Assessment (DAWBA), may aid detection and diagnosis of emotional disorders but there is limited real-world evidence of their clinical or cost effectiveness... Read More about The clinical and cost effectiveness of a STAndardised DIagnostic Assessment for children and adolescents with emotional difficulties (STADIA); multi- centre randomised controlled trial.

Investigating the fluid and electrolyte prescribing knowledge of foundation year doctors (2025)
Journal Article
Johnson, D., Houdmont, J., Levy, N., & Lobo, D. N. (in press). Investigating the fluid and electrolyte prescribing knowledge of foundation year doctors. Annals of The Royal College of Surgeons of England,

Recombinant Human Tissue Kallikrein-1 for Treating Acute Ischemic Stroke and Preventing Recurrence (2025)
Journal Article
Kasner, S. E., Bath, P. M., Hill, M. D., Volpi, J. J., Giuffre, M., Masuoka, L., Wambeke, D., & Madeddu, P. R. (2025). Recombinant Human Tissue Kallikrein-1 for Treating Acute Ischemic Stroke and Preventing Recurrence. Stroke, https://doi.org/10.1161/STROKEAHA.124.048858

Novel strategies are needed for the treatment of acute ischemic stroke when revascularization therapies are not clinically appropriate or are unsuccessful. Recombinant human tissue kallikrein-1 (rKLK1), a bradykinin-producing enzyme, offers a promis... Read More about Recombinant Human Tissue Kallikrein-1 for Treating Acute Ischemic Stroke and Preventing Recurrence.

Arterial spin labelling perfusion MRI analysis for the Human Connectome Project Lifespan Ageing and Development studies (2025)
Journal Article
Kirk, T. F., McConnell, F. A. K., Toner, J., Craig, M. S., Carone, D., Li, X., Suzuki, Y., Coalson, T. S., Harms, M. P., Glasser, M. F., & Chappell, M. A. (2025). Arterial spin labelling perfusion MRI analysis for the Human Connectome Project Lifespan Ageing and Development studies. Imaging Neuroscience, https://doi.org/10.1162/imag_a_00444

The Human Connectome Project Lifespan studies cover the Development (5-21) and Aging (36-100+) phases of life. Arterial spin labelling (ASL) was included in the imaging protocol, resulting in one of the largest datasets collected to-date of high spat... Read More about Arterial spin labelling perfusion MRI analysis for the Human Connectome Project Lifespan Ageing and Development studies.

Outputs (444)