Outputs (167)

Listening efficiency in adult cochlear-implant users compared with normally-hearing controls at ecologically relevant signal-to-noise ratios (2023)
Journal Article
Perea Pérez, F., Hartley, D. E. H., Kitterick, P. T., Zekveld, A. A., Naylor, G., & Wiggins, I. M. (2023). Listening efficiency in adult cochlear-implant users compared with normally-hearing controls at ecologically relevant signal-to-noise ratios. Frontiers in Human Neuroscience, 17, Article 1214485. https://doi.org/10.3389/fnhum.2023.1214485

Introduction: Due to having to work with an impoverished auditory signal, cochlear-implant (CI) users may experience reduced speech intelligibility and/or increased listening effort in real-world listening situations, compared to their normally-heari... Read More about Listening efficiency in adult cochlear-implant users compared with normally-hearing controls at ecologically relevant signal-to-noise ratios.

TNF-α evokes blood-brain barrier dysfunction through activation of Rho-kinase and neurokinin 1 receptor (2023)
Journal Article
Gao, X., & Bayraktutan, U. (2023). TNF-α evokes blood-brain barrier dysfunction through activation of Rho-kinase and neurokinin 1 receptor. Immunobiology, 228(5), Article 152706. https://doi.org/10.1016/j.imbio.2023.152706

Ischaemic stroke, accompanied by neuroinflammation, impairs blood–brain barrier (BBB) integrity through a complex mechanism involving activation of both RhoA/Rho kinase/myosin light chain-2 and neurokinin 1 receptor (NK1R). Using an in vitro model of... Read More about TNF-α evokes blood-brain barrier dysfunction through activation of Rho-kinase and neurokinin 1 receptor.

Risk of COVID-19 in people with multiple sclerosis who are seronegative following vaccination (2023)
Journal Article
Zaloum, S. A., Wood, C. H., Tank, P., Upcott, M., Vickaryous, N., Anderson, V., Baker, D., Chance, R., Evangelou, N., George, K., Giovannoni, G., Harding, K. E., Hibbert, A., Ingram, G., Jolles, S., Kang, A. S., Loveless, S., Moat, S. J., Richards, A., Robertson, N. P., …Tallantyre, E. C. (2023). Risk of COVID-19 in people with multiple sclerosis who are seronegative following vaccination. Multiple Sclerosis Journal, 29(8), 979-989. https://doi.org/10.1177/13524585231185247

Background:

People with multiple sclerosis (pwMS) treated with certain disease-modifying therapies (DMTs) have attenuated IgG response following COVID-19 vaccination; however, the clinical consequences remain unclear.

Objective:

To report CO... Read More about Risk of COVID-19 in people with multiple sclerosis who are seronegative following vaccination.

“It’s not just for the Past but it’s for the Here and Now”: Gift-Giver Perspectives on the Memory Machine to Gift Digital Memories (2023)
Presentation / Conference Contribution
Gibson, R., Babbage, C. M., Wagner, H. G., Price, D. J., Martindale, S., Chadborn, N. H., Ito-Jaeger, S., Darzentas, D. P., Webb, H., Jacobs, R., Atabey, A., Koleva, B., Flintham, M., Winklhofer, H., Urquhart, L. D., & Perez Vallejos, E. (2023, July). “It’s not just for the Past but it’s for the Here and Now”: Gift-Giver Perspectives on the Memory Machine to Gift Digital Memories. Presented at DIS '23: Designing Interactive Systems Conference, Pittsburgh, USA

We present the design of the Memory Machine (MeMa), a technology probe that can store, contextualise, and document media to represent memories. We accumulate vast physical and digital possessions throughout our lives, making it difficult to distingui... Read More about “It’s not just for the Past but it’s for the Here and Now”: Gift-Giver Perspectives on the Memory Machine to Gift Digital Memories.

A systematic review of ambulance service-based randomised controlled trials in stroke (2023)
Journal Article
Dixon, M., Appleton, J. P., Siriwardena, A. N., Williams, J., & Bath, P. M. (2023). A systematic review of ambulance service-based randomised controlled trials in stroke. Neurological Sciences, 44(12), 4363-4378. https://doi.org/10.1007/s10072-023-06910-w

Background: Treatment for stroke is time-dependent, and ambulance services play a vital role in the early recognition, assessment and transportation of stroke patients. Innovations which begin in ambulance services to expedite delivery of treatments... Read More about A systematic review of ambulance service-based randomised controlled trials in stroke.

Examining the Use of Autonomous Systems for Home Health Support using a Smart Mirror (2023)
Preprint / Working Paper
Dowthwaite, L., Reyez Cruz, G., Pena, A. R., Pepper, C., Jäger, N., Barnard, P., Hughes, A.-M., Nair, R. D., Crepaz-Keay, D., Cobb, S., & Benford, S. Examining the Use of Autonomous Systems for Home Health Support using a Smart Mirror

The home is becoming a key location for healthcare delivery, including the use of technology driven by autonomous systems (AS) to monitor and support healthcare plans. Using the example of a smart mirror, this paper describes the outcomes of focus gr... Read More about Examining the Use of Autonomous Systems for Home Health Support using a Smart Mirror.

Optimising the analysis of vascular prevention trials: Re-Assessment of the TARDIS trial, the first prevention trial to adopt an ordinal primary outcome measure (2023)
Journal Article
Woodhouse, L. J., Montgomery, A. A., Pocock, S., James, M., Ranta, A., Bath, P. M., & TARDIS Investigators, T. I. (2023). Optimising the analysis of vascular prevention trials: Re-Assessment of the TARDIS trial, the first prevention trial to adopt an ordinal primary outcome measure. Contemporary Clinical Trials Communications, 35, Article 101186. https://doi.org/10.1016/j.conctc.2023.101186

Background: Ordinalised vascular outcomes incorporating event severity are more informative than binary outcomes that just include event numbers. The TARDIS trial was the first vascular prevention study to use an ordinalised vascular outcome as its p... Read More about Optimising the analysis of vascular prevention trials: Re-Assessment of the TARDIS trial, the first prevention trial to adopt an ordinal primary outcome measure.

TrustScapes: A Visualisation Tool to Capture Stakeholders’ Concerns and Recommendations About Data Protection, Algorithmic Bias, and Online Safety (2023)
Journal Article
Ito-Jaeger, S., Lane, G., Dowthwaite, L., Webb, H., Patel, M., Rawsthorne, M., Portillo, V., Jirotka, M., & Perez Vallejos, E. (2023). TrustScapes: A Visualisation Tool to Capture Stakeholders’ Concerns and Recommendations About Data Protection, Algorithmic Bias, and Online Safety. International Journal of Qualitative Methods, 22, https://doi.org/10.1177/16094069231186965

This paper presents a new methodological approach, TrustScapes, an open access tool designed to identify and visualise stakeholders’ concerns and policy recommendations on data protection, algorithmic bias, and online safety for a fairer and more tru... Read More about TrustScapes: A Visualisation Tool to Capture Stakeholders’ Concerns and Recommendations About Data Protection, Algorithmic Bias, and Online Safety.

TrustScapes: A visualisation tool to capture stakeholders' concerns and recommendations about data protection, algorithmic bias, and online safety (2023)
Journal Article
Ito-Jaeger, S., Lane, G., Dowthwaite, L., Webb, H., Patel, M., Rawsthorne, M., Portillo, V., Jirotka, M., & Perez Vallejos, E. (2023). TrustScapes: A visualisation tool to capture stakeholders' concerns and recommendations about data protection, algorithmic bias, and online safety. International Journal of Qualitative Methods, 22, 1-10. https://doi.org/10.1177/1609406923118696

This paper presents a new methodological approach, TrustScapes, an open access tool designed to identify and visualise stakeholders’ concerns and policy recommendations on data protection, algorithmic bias, and online safety for a fairer and more tru... Read More about TrustScapes: A visualisation tool to capture stakeholders' concerns and recommendations about data protection, algorithmic bias, and online safety.

A predictive model of carer resilience in dementia family caregiving: A structural equation modelling approach (2023)
Journal Article
Leung, P., Orrell, M., Yates, L., & Orgeta, V. (2023). A predictive model of carer resilience in dementia family caregiving: A structural equation modelling approach. International Journal of Geriatric Psychiatry, 38(7), Article e5945. https://doi.org/10.1002/gps.5945

Objectives: This study aimed to investigate the mediating effects of quality of the caregiving relationship and other carer and person with dementia variables in predicting carer resilience over time. Method: Carers of people with mild and moderate d... Read More about A predictive model of carer resilience in dementia family caregiving: A structural equation modelling approach.