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Ocrelizumab B cell depletion has no effect on HERV RNA expression in PBMC in MS patients (2024)
Journal Article
Tarlinton, R., Tanasescu, R., Shannon-Lowe, C., & Gran, B. (2024). Ocrelizumab B cell depletion has no effect on HERV RNA expression in PBMC in MS patients. Multiple Sclerosis and Related Disorders, 86, Article 105597. https://doi.org/10.1016/j.msard.2024.105597

Background
Epstein barr virus (EBV) infection of B cells is now understood to be one of the triggering events for the development of Multiple Sclerosis (MS), a progressive immune-mediated disease of the central nervous system. EBV infection is also... Read More about Ocrelizumab B cell depletion has no effect on HERV RNA expression in PBMC in MS patients.

Ocrelizumab B cell depletion has no effect on HERV RNA expression in PBMC in MS patients (2023)
Preprint / Working Paper
Tarlinton, R., Tanescu, R., Shannon-Lowe, C., & Gran, B. (2023). Ocrelizumab B cell depletion has no effect on HERV RNA expression in PBMC in MS patients

Background Epstein Barr Virus (EBV) infection of B cells is now understood to be one of the triggering events for the development of Multiple Sclerosis (MS), a progressive immune-mediated disease of the central nervous system. EBV infection is also l... Read More about Ocrelizumab B cell depletion has no effect on HERV RNA expression in PBMC in MS patients.

Human endogenous retroviruses and multiple sclerosis: Causation, association, or after-effect? (2017)
Journal Article
Morandi, E., Tarlinton, R. E., Tanasescu, R., & Gran, B. (2017). Human endogenous retroviruses and multiple sclerosis: Causation, association, or after-effect?. Multiple Sclerosis Journal, 23(8), 1050-1055. https://doi.org/10.1177/1352458517704711

© The Author(s), 2016. From the early days of MS discovery, infections have been proposed as a possible cause of the disease. In the last three decades, an association between human endogenous retrovirus expression and MS has been further investigate... Read More about Human endogenous retroviruses and multiple sclerosis: Causation, association, or after-effect?.