Skip to main content

Research Repository

Advanced Search

Outputs (28)

Comparison of the Diagnostic Performance of the Central Vein Sign and CSF Oligoclonal Bands Supporting the Diagnosis of Multiple Sclerosis (2025)
Journal Article
Allen, C. M., Clarke, M. A., Pai, H. V., Cauchi, M., Hawken, J., Htet, Z. M., Allen-Philbey, K., Mohamed, B., Fitzsimmons, D., Das Nair, R., Morgan, P., Partlett, C., Dineen, R. A., Schmierer, K., Tallantyre, E. C., & Evangelou, N. (2025). Comparison of the Diagnostic Performance of the Central Vein Sign and CSF Oligoclonal Bands Supporting the Diagnosis of Multiple Sclerosis. Neurology Open Access, 1(2), Article e000017. https://doi.org/10.1212/WN9.0000000000000017

Background and Objectives
The central vein sign (CVS) describes the presence of venules within multiple sclerosis (MS) brain lesions, visible on T2*-weighted MRI. In the upcoming revision of the MS diagnostic criteria, the simplified “rule of 6” (i.... Read More about Comparison of the Diagnostic Performance of the Central Vein Sign and CSF Oligoclonal Bands Supporting the Diagnosis of Multiple Sclerosis.

T₁-Dark Rim as a Marker of New and Chronic Active Multiple Sclerosis Lesions: A Serial Study With Frequent 7T MRI (2025)
Journal Article
Marshall, M., Aphiwatthanasumet, K., Mougin, O., Stadelmann, C., Morgan, P. S., Dineen, R. A., Gowland, P., Evangelou, N., & Clarke, M. A. (2025). T₁-Dark Rim as a Marker of New and Chronic Active Multiple Sclerosis Lesions: A Serial Study With Frequent 7T MRI. Journal of Neuroimaging, 35(3), Article e70044. https://doi.org/10.1111/jon.70044

Background and Purpose:
Chronic active multiple sclerosis (MS) lesions represent a particularly destructive subset of lesions on pathology. However, their imaging correlates, including paramagnetic rim lesions (PRLs) detected on susceptibility-weig... Read More about T₁-Dark Rim as a Marker of New and Chronic Active Multiple Sclerosis Lesions: A Serial Study With Frequent 7T MRI.

Magnetic Resonance Imaging of Inner Ear and Internal Auditory Canal Structures in the Presence of a Cochlear Implant (2025)
Journal Article
Dewey, R. S., Dineen, R. A., Clemence, M., Menon, N., Bowtell, R., Boyle, P., & Hartley, D. E. H. (2025). Magnetic Resonance Imaging of Inner Ear and Internal Auditory Canal Structures in the Presence of a Cochlear Implant. Otology and Neurotology, 46(4), e105-e108. https://doi.org/10.1097/mao.0000000000004445

Objective
To determine whether the internal auditory canal (IAC) can be visualized using magnetic resonance imaging (MRI) in users of a cochlear implant (CI) model that can safely undergo MRI at 3 T.

Patients
Four normally hearing controls and... Read More about Magnetic Resonance Imaging of Inner Ear and Internal Auditory Canal Structures in the Presence of a Cochlear Implant.

Automated characterisation of cerebral microbleeds using their size and spatial distribution on brain MRI (2025)
Journal Article
Sundaresan, V., Zamboni, G., Dineen, R. A., Auer, D. P., Sotiropoulos, S. N., Sprigg, N., Jenkinson, M., & Griffanti, L. (2025). Automated characterisation of cerebral microbleeds using their size and spatial distribution on brain MRI. European Radiology Experimental, 9(1), Article 5. https://doi.org/10.1186/s41747-024-00544-z

Cerebral microbleeds (CMBs) are small, hypointense hemosiderin deposits in the brain measuring 2–10 mm in diameter. As one of the important biomarkers of small vessel disease, they have been associated with various neurodegenerative and cerebrovascul... Read More about Automated characterisation of cerebral microbleeds using their size and spatial distribution on brain MRI.

Diagnostic performance of axial T2-weighted MRI sequence for exclusion of brain tumour in paediatric patients with non-localizing symptoms (2024)
Journal Article
Gerrish, A. C., Malik, L., Swain, C., Thomas, A. G., Jaspan, T., & Dineen, R. A. (2024). Diagnostic performance of axial T2-weighted MRI sequence for exclusion of brain tumour in paediatric patients with non-localizing symptoms. British Journal of Radiology, https://doi.org/10.1093/bjr/tqae244

Objective
To establish diagnostic performance of a single axial T2-weighted sequence for detection of brain tumours in children with non-localizing symptoms, compared to a standard MRI protocol.

Methods
Retrospective analysis of children undergo... Read More about Diagnostic performance of axial T2-weighted MRI sequence for exclusion of brain tumour in paediatric patients with non-localizing symptoms.

Effect of Proximal Blood Flow Arrest During Endovascular Thrombectomy (ProFATE): a multicentre, blinded-endpoint, randomised clinical trial (2024)
Journal Article
Dhillon, P. S., Butt, W., Podlasek, A., Bhogal, P., Lynch, J., Booth, T. C., McConachie, N., Lenthall, R., Nair, S., Malik, L., Goddard, T., Carraro Do Nascimento, V., Barrett, E., Jethwa, K., Krishnan, K., Dineen, R. A., & England, T. J. (in press). Effect of Proximal Blood Flow Arrest During Endovascular Thrombectomy (ProFATE): a multicentre, blinded-endpoint, randomised clinical trial. Stroke,

Background
The effect of temporary blood flow arrest during endovascular thrombectomy (EVT) for acute ischaemic stroke (AIS) is uncertain due to the lack of evidence from randomised controlled trials (RCT). We aimed to investigate whether temporary... Read More about Effect of Proximal Blood Flow Arrest During Endovascular Thrombectomy (ProFATE): a multicentre, blinded-endpoint, randomised clinical trial.

Comparison of Echo Planar and Turbo Spin Echo Diffusion‐Weighted Imaging in Intraoperative MRI (2024)
Journal Article
Thorpe, J. C., Thust, S. C., Gillon, C. H., Rowe, S., Swain, C. E., MacArthur, D. C., Howarth, S. P., Avula, S., Morgan, P. S., & Dineen, R. A. (2025). Comparison of Echo Planar and Turbo Spin Echo Diffusion‐Weighted Imaging in Intraoperative MRI. Journal of Magnetic Resonance Imaging, 61(4), 1847-1857. https://doi.org/10.1002/jmri.29614

Background
Diffusion-weighted imaging (DWI) is routinely used in brain tumor surgery guided by intraoperative MRI (IoMRI). However, conventional echo planar imaging DWI (EPI-DWI) is susceptible to distortion and artifacts that affect image quality.... Read More about Comparison of Echo Planar and Turbo Spin Echo Diffusion‐Weighted Imaging in Intraoperative MRI.

Endovascular thrombectomy vs best medical management for late presentation acute ischaemic stroke with large vessel occlusion without CT perfusion or MR imaging selection: A systematic review and meta-analysis (2024)
Journal Article
Dhillon, P. S., Marei, O., Podlasek, A., Butt, W., Rice, H., de Villiers, L., Carraro do Nascimento, V., McConachie, N., Lenthall, R., Nair, S., Malik, L., Bhogal, P., Dineen, R. A., & England, T. J. (2024). Endovascular thrombectomy vs best medical management for late presentation acute ischaemic stroke with large vessel occlusion without CT perfusion or MR imaging selection: A systematic review and meta-analysis. Journal of Stroke and Cerebrovascular Diseases, 33(11), Article 108002. https://doi.org/10.1016/j.jstrokecerebrovasdis.2024.108002

Background: The efficacy and safety of endovascular thrombectomy (EVT) beyond 6 hours from stroke onset for patients with large vessel occlusion (LVO) selected without CT perfusion(CTP) or MR imaging(MRI) is undetermined. We conducted a systematic re... Read More about Endovascular thrombectomy vs best medical management for late presentation acute ischaemic stroke with large vessel occlusion without CT perfusion or MR imaging selection: A systematic review and meta-analysis.