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Outputs (19)

Noninvasive Monitoring of Palmitoyl Hexapeptide-12 in Human Skin Layers: Mechanical Interaction with Skin Components and Its Potential Skincare Benefits (2025)
Journal Article
Ligorio, C., Tavasoli, E., Karaman-Jurukovska, N., Ittycheri, A., Kotowska, A. M., Khan, M. H., Scurr, D. J., Gupta, S. A., Moogan, L. V., Emmetsberger, J., Lu, F., German, G. K., Mammone, T., & Mata, A. (2025). Noninvasive Monitoring of Palmitoyl Hexapeptide-12 in Human Skin Layers: Mechanical Interaction with Skin Components and Its Potential Skincare Benefits. ACS Applied Bio Materials, 8(3), 2340-2355. https://doi.org/10.1021/acsabm.4c01816

Self-assembling peptides (SAPs) represent a rich source of building blocks that interact with biological structures. For instance, cosmetic SAPs like Palmitoyl hexapeptide-12 have gained increasing interest for their anti-aging properties. However, t... Read More about Noninvasive Monitoring of Palmitoyl Hexapeptide-12 in Human Skin Layers: Mechanical Interaction with Skin Components and Its Potential Skincare Benefits.

Effect of supramolecular peptide hydrogel scaffold charge on HepG2 viability and spheroid formation (2024)
Journal Article
Xin, Y., Ligorio, C., O’brien, M., Collins, R., Dong, S., Miller, A. F., Saiani, A., & Gough, J. E. (2024). Effect of supramolecular peptide hydrogel scaffold charge on HepG2 viability and spheroid formation. Journal of Materials Chemistry B, 12(48), 12553–12566. https://doi.org/10.1039/d4tb01701c

Supramolecular bioinspired self-assembling peptide hydrogel (SAPH) scaffolds represent a class of fully defined synthetic materials whose chemical and mechanical properties can be finely engineered. In this study, the relationship between SAPHs physi... Read More about Effect of supramolecular peptide hydrogel scaffold charge on HepG2 viability and spheroid formation.

Biocooperative Regenerative Materials by Harnessing Blood-Clotting and Peptide Self-Assembly (2024)
Journal Article
Padilla-Lopategui, S., Ligorio, C., Bu, W., Yin, C., Laurenza, D., Redondo, C., Owen, R., Sun, H., Rose, F. R., Iskratsch, T., & Mata, A. (2024). Biocooperative Regenerative Materials by Harnessing Blood-Clotting and Peptide Self-Assembly. Advanced Materials, 36(52), Article 2407156. https://doi.org/10.1002/adma.202407156

The immune system has evolved to heal small ruptures and fractures with remarkable efficacy through regulation of the regenerative hematoma (RH); a rich and dynamic environment that coordinates numerous molecular and cellular processes to achieve com... Read More about Biocooperative Regenerative Materials by Harnessing Blood-Clotting and Peptide Self-Assembly.

Biofabrication and biomanufacturing in Ireland and the UK (2024)
Journal Article
Murphy, J. F., Lavelle, M., Asciak, L., Burdis, R., Levis, H. J., Ligorio, C., McGuire, J., Polleres, M., Smith, P. O., Tullie, L., Uribe-Gomez, J., Chen, B., Dawson, J. I., Gautrot, J. E., Hooper, N. M., Kelly, D. J., Li, V. S. W., Mata, A., Pandit, A., Phillips, J. B., …Huang, Y. Y. S. (2024). Biofabrication and biomanufacturing in Ireland and the UK. Bio-Design and Manufacturing, 7(6), 825-856. https://doi.org/10.1007/s42242-024-00316-z

As we navigate the transition from the Fourth to the Fifth Industrial Revolution, the emerging fields of biomanufacturing and biofabrication are transforming life sciences and healthcare. These sectors are benefiting from a synergy of synthetic and e... Read More about Biofabrication and biomanufacturing in Ireland and the UK.

Disassembly of self-assembling peptide hydrogels as a versatile method for cell extraction and manipulation (2024)
Journal Article
Ligorio, C., Martinez-Espuga, M., Laurenza, D., Hartley, A., Rodgers, C. B., Kotowska, A. M., Scurr, D. J., Dalby, M. J., Ordóñez-Morán, P., & Mata, A. (2024). Disassembly of self-assembling peptide hydrogels as a versatile method for cell extraction and manipulation. Journal of Materials Chemistry B, 12(46), 11939-11952. https://doi.org/10.1039/D4TB01575D

Self-assembling peptide hydrogels (SAPHs) are increasingly being used as two-dimensional (2D) cell culture substrates and three-dimensional (3D) matrices due to their tunable properties and biomimicry of native tissues. Despite these advantages, SAPH... Read More about Disassembly of self-assembling peptide hydrogels as a versatile method for cell extraction and manipulation.

084 Cosmetic peptide penetration and assembly in human skin: A label-free approach (2024)
Presentation / Conference Contribution
Ligorio, C., Kotowska, A., Scurr, D., Tavasoli, E., Karaman-Jurukovska, N., Mata, A., Moogan, L., German, G., Lu, F., & Mammone, T. (2024, May). 084 Cosmetic peptide penetration and assembly in human skin: A label-free approach. Presented at Society for Investigative Dermatology (SID) 2024 Meeting, Dallas, TX

Collagen-like Osteoclast-Associated Receptor (OSCAR)-Binding Motifs Show a Co-Stimulatory Effect on Osteoclastogenesis in a Peptide Hydrogel System (2023)
Journal Article
Vitale, M., Ligorio, C., Richardson, S. M., Hoyland, J. A., & Bella, J. (2023). Collagen-like Osteoclast-Associated Receptor (OSCAR)-Binding Motifs Show a Co-Stimulatory Effect on Osteoclastogenesis in a Peptide Hydrogel System. International Journal of Molecular Sciences, 25(1), Article 445. https://doi.org/10.3390/ijms25010445

Osteoclastogenesis, one of the dynamic pathways underlying bone remodelling, is a complex process that includes many stages. This complexity, while offering a wealth of therapeutic opportunities, represents a substantial challenge in unravelling the... Read More about Collagen-like Osteoclast-Associated Receptor (OSCAR)-Binding Motifs Show a Co-Stimulatory Effect on Osteoclastogenesis in a Peptide Hydrogel System.

Co-assembling living material as an in vitro lung epithelial infection model (2023)
Journal Article
Wu, Y., Romero, M., Robertson, S. N., Fenn, S., Fisher, L., Willingham, I., Martinez Pomares, L., Ligorio, C., Hill, J., Bu, W., Zhou, Z., Wildman, R. D., Ghaemmaghami, A. M., Sun, H., Sun, J., Cámara, M., & Mata, A. (2024). Co-assembling living material as an in vitro lung epithelial infection model. Matter, 7(1), 216-236. https://doi.org/10.1016/j.matt.2023.10.029

Biofilms are robust living 3D materials that play key roles in nature but also cause major problems, such as tolerance to antibiotic treatment. Recreation of these living structures in vitro is critical to understand their biology and develop solutio... Read More about Co-assembling living material as an in vitro lung epithelial infection model.

Nanocrystalline Cellulose as a Versatile Engineering Material for Extrusion-Based Bioprinting (2023)
Journal Article
A. Read, S., Shuen Go, C., J. S. Ferreira, M., Ligorio, C., Kimber, S., G. Dumanli, A., & Domingos, M. (2023). Nanocrystalline Cellulose as a Versatile Engineering Material for Extrusion-Based Bioprinting. Pharmaceutics, 15(10), Article 2432. https://doi.org/10.3390/pharmaceutics15102432

Naturally derived polysaccharide-based hydrogels, such as alginate, are frequently used in the design of bioinks for 3D bioprinting. Traditionally, the formulation of such bioinks requires the use of pre-reticulated materials with low viscosities, wh... Read More about Nanocrystalline Cellulose as a Versatile Engineering Material for Extrusion-Based Bioprinting.