Biofabrication and biomanufacturing in Ireland and the UK

Murphy, Jack F.; Lavelle, Martha; Asciak, Lisa; Burdis, Ross; Levis, Hannah J.; Ligorio, Cosimo; McGuire, Jamie; Polleres, Marlene; Smith, Poppy O.; Tullie, Lucinda; Uribe-Gomez, Juan; Chen, Biqiong; Dawson, Jonathan I.; Gautrot, Julien E.; Hooper, Nigel M.; Kelly, Daniel J.; Li, Vivian S. W.; Mata, Alvaro; Pandit, Abhay; Phillips, James B.; Shu, Wenmiao; Stevens, Molly M.; Williams, Rachel L.; Armstrong, James P. K.; Huang, Yan Yan Shery

Abstract

As we navigate the transition from the Fourth to the Fifth Industrial Revolution, the emerging fields of biomanufacturing and biofabrication are transforming life sciences and healthcare. These sectors are benefiting from a synergy of synthetic and engineering biology, sustainable manufacturing, and integrated design principles. Advanced techniques such as 3D bioprinting, tissue engineering, directed assembly, and self-assembly are instrumental in creating biomimetic scaffolds, tissues, organoids, medical devices, and biohybrid systems. The field of biofabrication in the United Kingdom and Ireland is emerging as a pivotal force in bioscience and healthcare, propelled by cutting-edge research and development. Concentrating on the production of biologically functional products for use in drug delivery, in vitro models, and tissue engineering, research institutions across these regions are dedicated to innovating healthcare solutions that adhere to ethical standards while prioritising sustainability, affordability, and healthcare system benefits.

Citation

Murphy, J. F., Lavelle, M., Asciak, L., Burdis, R., Levis, H. J., Ligorio, C., McGuire, J., Polleres, M., Smith, P. O., Tullie, L., Uribe-Gomez, J., Chen, B., Dawson, J. I., Gautrot, J. E., Hooper, N. M., Kelly, D. J., Li, V. S. W., Mata, A., Pandit, A., Phillips, J. B., …Huang, Y. Y. S. (2024). Biofabrication and biomanufacturing in Ireland and the UK. Bio-Design and Manufacturing, 7(6), 825-856. https://doi.org/10.1007/s42242-024-00316-z

• Journal Article Type: Article
• Acceptance Date: Aug 11, 2024
• Online Publication Date: Oct 23, 2024
• Publication Date: 2024-11
• Deposit Date: Feb 23, 2025
• Publicly Available Date: Feb 25, 2025
• Journal: Bio-Design and Manufacturing
• Print ISSN: 2096-5524
• Electronic ISSN: 2522-8552
• Publisher: Springer Nature
• Peer Reviewed: Peer Reviewed
• Volume: 7
• Issue: 6
• Pages: 825-856
• DOI: https://doi.org/10.1007/s42242-024-00316-z
• Public URL: https://nottingham-repository.worktribe.com/output/45848975
• Publisher URL: https://link.springer.com/article/10.1007/s42242-024-00316-z
• Additional Information: Received: 12 April 2024; Accepted: 11 August 2024; First Online: 23 October 2024; : ; : YYSH is an associate editor for Bio-Design and Manufacturing and was not involved in the editorial review or the decision to publish this article. The authors declare that they have no conflict of interest.; : This study does not contain any studies with human or animal subjects performed by any of the authors.