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Outputs (3)

Hypoxia-inducible factor-1α is involved in the pro-angiogenic effect of hydrogen sulfide under hypoxic stress (2010)
Journal Article
Liu, X. H., Pan, L. L., Zhuo, Y., Gong, Q. H., Rose, P., & Zhu, Y. Z. (2010). Hypoxia-inducible factor-1α is involved in the pro-angiogenic effect of hydrogen sulfide under hypoxic stress. Biological and Pharmaceutical Bulletin, 33(9), 1550-1554. https://doi.org/10.1248/bpb.33.1550

Hydrogen sulfide (H2S) is known to have pro-angiogenic properties in mammals. In this study, we examined H2S played the role in pro-angiogenesis mediated by hypoxia-inducible factor (HIF)-1α under hypoxic conditions. Rat brain capillary endothelial c... Read More about Hypoxia-inducible factor-1α is involved in the pro-angiogenic effect of hydrogen sulfide under hypoxic stress.

The effect of hydrogen sulfide donors on lipopolysaccharide-induced formation of inflammatory mediators in macrophages (2010)
Journal Article
Whiteman, M., Li, L., Rose, P., Tan, C. H., Parkinson, D. B., & Moore, P. K. (2010). The effect of hydrogen sulfide donors on lipopolysaccharide-induced formation of inflammatory mediators in macrophages. Antioxidants and Redox Signaling, 12(10), 1147-1154. https://doi.org/10.1089/ars.2009.2899

The role of hydrogen sulfide (H2S) in inflammation is controversial, with both pro- and antiinflammatory effects documented. Many studies have used simple sulfide salts as the source of H2S, which give a rapid bolus of H2S in aqueous solutions and th... Read More about The effect of hydrogen sulfide donors on lipopolysaccharide-induced formation of inflammatory mediators in macrophages.

Protective effects of cysteine analogues on acute myocardial ischemia: Novel modulators of endogenous H2S production (2010)
Journal Article
Wang, Q., Wang, X. L., Liu, H. R., Rose, P., & Zhu, Y. Z. (2010). Protective effects of cysteine analogues on acute myocardial ischemia: Novel modulators of endogenous H2S production. Antioxidants and Redox Signaling, 12(10), 1155-1165. https://doi.org/10.1089/ars.2009.2947

The current study was designed to evaluate the pharmacologic effects of three novel cysteine-containing compounds: S-propyl-l-cysteine (SPC), S-allyl-l-cysteine (SAC), and S-propargyl-l-cysteine (SPRC) on H2S production and antioxidant defenses in an... Read More about Protective effects of cysteine analogues on acute myocardial ischemia: Novel modulators of endogenous H2S production.