Outputs (65)

Increased Responses to the Actions of Fibroblast Growth Factor 21 on Energy Balance and Body Weight in a Seasonal Model of Adiposity (2012)
Journal Article
Murphy, M., Samms, R., Warner, A., Bolborea, M., Barrett, P., Fowler, M. J., Brameld, J. M., Tsintzas, K., Kharitonenkov, A., Adams, A. C., Coskun, T., & Ebling, F. J. (2013). Increased Responses to the Actions of Fibroblast Growth Factor 21 on Energy Balance and Body Weight in a Seasonal Model of Adiposity. Journal of Neuroendocrinology, 25(2), 180-189. https://doi.org/10.1111/j.1365-2826.2012.02383.x

The present study aimed to investigate the actions of fibroblast growth factor 21 (FGF21) on energy balance in a natural model of relative fatness, the Siberian hamster. Hamsters were studied under long days (LD) to promote weight gain, or short days... Read More about Increased Responses to the Actions of Fibroblast Growth Factor 21 on Energy Balance and Body Weight in a Seasonal Model of Adiposity.

Effects of manipulating hypothalamic triiodothyronine concentrations on seasonal body weight and torpor cycles in Siberian hamsters (2012)
Journal Article
Murphy, M., Jethwa, P. H., Warner, A., Barrett, P., Nilaweera, K. N., Brameld, J. M., & Ebling, F. J. (2012). Effects of manipulating hypothalamic triiodothyronine concentrations on seasonal body weight and torpor cycles in Siberian hamsters. Endocrinology, 153(1), 101-112. https://doi.org/10.1210/en.2011-1249

Siberian hamsters display photoperiodically regulated annual cycles in body weight, appetite, and reproduction. Previous studies have revealed a profound up-regulation of type 3 deiodinase (DIO3) mRNA in the ventral ependyma of the hypothalamus assoc... Read More about Effects of manipulating hypothalamic triiodothyronine concentrations on seasonal body weight and torpor cycles in Siberian hamsters.

Myosin heavy chain mRNA isoforms are expressed in two distinct cohorts during C2C12 myogenesis (2011)
Journal Article
Brown, D. M., Parr, T., & Brameld, J. M. (2012). Myosin heavy chain mRNA isoforms are expressed in two distinct cohorts during C2C12 myogenesis. Journal of Muscle Research and Cell Motility, 32(6), 383-390. https://doi.org/10.1007/s10974-011-9267-4

The regulation of muscle fibre transitions has mainly been studied in vivo using conventional histological or immunohistochemical techniques. In order to investigate the molecular regulation of myosin heavy chain (MyHC) isoform expression in cell cul... Read More about Myosin heavy chain mRNA isoforms are expressed in two distinct cohorts during C2C12 myogenesis.

Regional variation in angiotensin converting enzyme activity in the human placenta (2011)
Journal Article
Brameld, J. M., Hold, R., & Broughton Pipkin, F. (2011). Regional variation in angiotensin converting enzyme activity in the human placenta. Placenta, 32(11), 906-908. https://doi.org/10.1016/j.placenta.2011.07.085

Sensitivity of chorionic plate arteries to angiotensin II (AngII) is greatest at the placental periphery. Angiotensin converting enzyme (ACE) is central to the synthesis of AngII and is present in the placental vasculature. We measured vascular ACE a... Read More about Regional variation in angiotensin converting enzyme activity in the human placenta.

Use of the Affymetrix human GeneChip array and genomic DNA hybridisation probe selection to study ovine transcriptomes (2011)
Journal Article
Graham, N. S., May, S. T., Daniel, Z. C., Emmerson, Z. F., Brameld, J. M., & Parr, T. (2011). Use of the Affymetrix human GeneChip array and genomic DNA hybridisation probe selection to study ovine transcriptomes. Animal, 5(6), 861-866. https://doi.org/10.1017/S1751731110002533

Affymetrix GeneChip microarrays are a powerful tool to study global gene expression profiles and have been used on many species. However, no sheep-specific Affymetrix GeneChip is currently available and the bovine array is fairly limited in its cover... Read More about Use of the Affymetrix human GeneChip array and genomic DNA hybridisation probe selection to study ovine transcriptomes.

Advances in research on the prenatal development of skeletal muscle in animals in relation to the quality of muscle-based food. I. Regulation of myogenesis and environmental impact (2011)
Journal Article
Rehfeldt, C., Te Pas, M. F., Wimmers, K., Brameld, J. M., Nissen, P. M., Berri, C., Valente, L. M., Power, D. M., Picard, B., Stickland, N. C., & Oksbjerg, N. (2011). Advances in research on the prenatal development of skeletal muscle in animals in relation to the quality of muscle-based food. I. Regulation of myogenesis and environmental impact. Animal, 5(5), 703-717. https://doi.org/10.1017/S1751731110002089

Skeletal muscle development in vertebrates - also termed myogenesis - is a highly integrated process. Evidence to date indicates that the processes are very similar across mammals, poultry and fish, although the timings of the various steps differ co... Read More about Advances in research on the prenatal development of skeletal muscle in animals in relation to the quality of muscle-based food. I. Regulation of myogenesis and environmental impact.

Advances in research on the prenatal development of skeletal muscle in animals in relation to the quality of muscle-based food. II - Genetic factors related to animal performance and advances in methodology (2011)
Journal Article
Rehfeldt, C., Te Pas, M. F., Wimmers, K., Brameld, J. M., Nissen, P. M., Berri, C., Valente, L. M., Power, D. M., Picard, B., Stickland, N. C., & Oksbjerg, N. (2011). Advances in research on the prenatal development of skeletal muscle in animals in relation to the quality of muscle-based food. II - Genetic factors related to animal performance and advances in methodology. Animal, 5(5), 718-730. https://doi.org/10.1017/S1751731110002454

Selective breeding is an effective tool to improve livestock. Several selection experiments have been conducted to study direct selection responses as well as correlated responses in traits of skeletal muscle growth and function. Moreover, comparison... Read More about Advances in research on the prenatal development of skeletal muscle in animals in relation to the quality of muscle-based food. II - Genetic factors related to animal performance and advances in methodology.

Biological mechanisms of fetal development relating to postnatal growth, efficiency and carcass characteristics in ruminants (2010)
Book Chapter
Brameld, J. M., Greenwood, P. L., & Bell, A. W. (2010). Biological mechanisms of fetal development relating to postnatal growth, efficiency and carcass characteristics in ruminants. In P. L. Greenwood, A. W. Bell, P. E. Vercoe, & G. J. Viljoen (Eds.), Managing the Prenatal Environment to Enhance Livestock Productivity (93-119). Springer Publishing Company. https://doi.org/10.1007/978-90-481-3135-8_4

Copyright © International Atomic Energy Agency 2010. All Rights Reserved. Over recent years there has been a lot of interest in the effects of prenatal environment on subsequent development of tissues and the postnatal consequences. In farm animal sp... Read More about Biological mechanisms of fetal development relating to postnatal growth, efficiency and carcass characteristics in ruminants.

Regulation of ovine and porcine stearoyl coenzyme A desaturase gene promoters by fatty acids and sterols (2010)
Journal Article
Zulkifli, R. M., Parr, T., Salter, A. M., & Brameld, J. M. (2010). Regulation of ovine and porcine stearoyl coenzyme A desaturase gene promoters by fatty acids and sterols. Journal of Animal Science, 88(8), 2565-2575. https://doi.org/10.2527/jas.2009-2603

Stearoyl CoA desaturase (SCD) is responsible for converting SFA into MUFA and plays an important role in regulating the fatty acid composition of tissues. Although the number of SCD isoforms differs among species, SCD-1 is the predominant isoform exp... Read More about Regulation of ovine and porcine stearoyl coenzyme A desaturase gene promoters by fatty acids and sterols.

Effects of photoperiod on daily locomotor activity, energy expenditure, and feeding behavior in a seasonal mammal (2010)
Journal Article
Warner, A., Jethwa, P. H., Wyse, C. A., I'Anson, H., Brameld, J. M., & Ebling, F. J. (2010). Effects of photoperiod on daily locomotor activity, energy expenditure, and feeding behavior in a seasonal mammal. AJP - Regulatory, Integrative and Comparative Physiology, 298(5), R1409-R1416. https://doi.org/10.1152/ajpregu.00279.2009

The objective of this study was to determine whether the previously observed effects of photoperiod on body weight in Siberian hamsters were due to changes in the daily patterns of locomotor activity, energy expenditure, and/or feeding behavior. Adul... Read More about Effects of photoperiod on daily locomotor activity, energy expenditure, and feeding behavior in a seasonal mammal.