Outputs (2)

Childhood environment influences epigenetic age and methylation concordance of a CpG clock locus in British-Bangladeshi migrants (2022)
Journal Article
Stöger, R., Choi, M., Begum, K., Leeman, G., Emes, R. D., Melamed, P., & Bentley, G. R. (2023). Childhood environment influences epigenetic age and methylation concordance of a CpG clock locus in British-Bangladeshi migrants. Epigenetics, 18(1), Article 2153511. https://doi.org/10.1080/15592294.2022.2153511

Migration from one location to another often comes with a change in environmental conditions. Here, we analysed features of DNA methylation in young, adult British-Bangladeshi women who experienced different environments during their childhoods: a) m... Read More about Childhood environment influences epigenetic age and methylation concordance of a CpG clock locus in British-Bangladeshi migrants.

Epigenetic regulation of 5α reductase-1 underlies adaptive plasticity of reproductive function and pubertal timing (2022)
Journal Article
Bar-Sadeh, B., Amichai, O. E., Pnueli, L., Begum, K., Leeman, G., Emes, R. D., Stöger, R., Bentley, G. R., & Melamed, P. (2022). Epigenetic regulation of 5α reductase-1 underlies adaptive plasticity of reproductive function and pubertal timing. BMC Biology, 20, Article 11. https://doi.org/10.1186/s12915-021-01219-6

Background: Women facing increased energetic demands in childhood commonly have altered adult ovarian activity and shorter reproductive lifespan, possibly comprising a strategy to optimize reproductive success. Here, we sought to understand the mecha... Read More about Epigenetic regulation of 5α reductase-1 underlies adaptive plasticity of reproductive function and pubertal timing.