Outputs (53)

Image processing and Quality Control for the first 10,000 brain imaging datasets from UK Biobank (2017)
Journal Article
Alfaro-Almagro, F., Jenkinson, M., Bangerter, N. K., Andersson, J. L., Griffanti, L., Douaud, G., Sotiropoulos, S. N., Jbabdi, S., Hernandez-Fernandez, M., Vallee, E., Vidaurre, D., Webster, M., McCarthy, P., Rorden, C., Daducci, A., Alexander, D. C., Zhang, H., Dragonu, I., Matthews, P. M., Miller, K. L., & Smith, S. M. (2018). Image processing and Quality Control for the first 10,000 brain imaging datasets from UK Biobank. NeuroImage, 166, https://doi.org/10.1016/j.neuroimage.2017.10.034

UK Biobank is a large-scale prospective epidemiological study with all data accessible to researchers worldwide. It is currently in the process of bringing back 100,000 of the original participants for brain, heart and body MRI, carotid ultrasound an... Read More about Image processing and Quality Control for the first 10,000 brain imaging datasets from UK Biobank.

Dynamics of large-scale electrophysiological networks: a technical review (2017)
Journal Article
O'Neill, G. C., Tewarie, P. K., Vidaurre, D., Liuzzi, L., Woolrich, M. W., & Brookes, M. J. (2017). Dynamics of large-scale electrophysiological networks: a technical review. NeuroImage, https://doi.org/10.1016/j.neuroimage.2017.10.003

For several years it has been argued that neural synchronisation is crucial for cognition. The idea that synchronised temporal patterns between different neural groups carries information above and beyond the isolated activity of these groups has ins... Read More about Dynamics of large-scale electrophysiological networks: a technical review.

Seven-Tesla magnetization transfer imaging to detect multiple sclerosis white matter lesions (2017)
Journal Article
Chou, I.-J., Lim, S.-Y., Tanasescu, R., Al-Radaideh, A., Mougin, O. E., Tench, C. R., Whitehouse, W. P., Gowland, P. A., & Constantinescu, C. S. (in press). Seven-Tesla magnetization transfer imaging to detect multiple sclerosis white matter lesions. Journal of Neuroimaging, https://doi.org/10.1111/jon.12474

BACKGROUND AND PURPOSE: Fluid-attenuated inversion recovery (FLAIR) imaging at 3 Tesla (T) field strength is the most sensitive modality for detecting white matter lesions in multiple sclerosis. While 7T FLAIR is effective in detecting cortical lesio... Read More about Seven-Tesla magnetization transfer imaging to detect multiple sclerosis white matter lesions.

Multiparametric renal magnetic resonance imaging: validation, interventions, and alterations in chronic kidney disease (2017)
Journal Article
Cox, E. F., Buchanan, C. E., Bradley, C. R., Prestwich, B., Mahmoud, H., Taal, M., Selby, N. M., & Francis, S. T. (2017). Multiparametric renal magnetic resonance imaging: validation, interventions, and alterations in chronic kidney disease. Frontiers in Physiology, 8, Article 696. https://doi.org/10.3389/fphys.2017.00696

Background: This paper outlines a multiparametric renal MRI acquisition and analysis protocol to allow non-invasive assessment of hemodynamics (renal artery blood flow and perfusion), oxygenation (BOLD T2*), and microstructure (diffusion, T1 mapping)... Read More about Multiparametric renal magnetic resonance imaging: validation, interventions, and alterations in chronic kidney disease.

Sodium MRI: a new frontier in imaging in nephrology (2017)
Journal Article
Francis, S. T., Buchanan, C., Prestwich, B., & Taal, M. W. (2017). Sodium MRI: a new frontier in imaging in nephrology. Current Opinion in Nephrology and Hypertension, 26(6), 435-441. https://doi.org/10.1097/MNH.0000000000000370

Purpose of review

This review focuses on the recent technological advances in quantitative sodium (23Na) MRI to provide a noninvasive measure of tissue viability for use in clinical studies of patients with kidney disease. 23Na MRI is the only non... Read More about Sodium MRI: a new frontier in imaging in nephrology.

Overdominant effect of a CHRNA4 polymorphism on cingulo-opercular network activity and cognitive control (2017)
Journal Article
Sadaghiani, S., Ng, B., Altmann, A., Poline, J.-B., Banaschewski, T., Bokde, A. L., Bromberg, U., Büchel, C., Quinlan, E. B., Conrod, P. J., Desrivières, S., Flor, H., Frouin, V., Garavan, H., Gowland, P. A., Gallinat, J., Heinz, A., Ittermann, B., Martinot, J.-L., Martinot, M.-L. P., …Greicius, M. (2017). Overdominant effect of a CHRNA4 polymorphism on cingulo-opercular network activity and cognitive control. Journal of Neuroscience, 37(40), 9657-9666. https://doi.org/10.1523/JNEUROSCI.0991-17.2017

The nicotinic system plays an important role in cognitive control, and is implicated in several neuropsychiatric conditions. Yet, the contributions of genetic variability in this system to individuals' cognitive control abilities are poorly understoo... Read More about Overdominant effect of a CHRNA4 polymorphism on cingulo-opercular network activity and cognitive control.

MRI assessment of the postprandial gastrointestinal motility and peptide response in healthy humans (2017)
Journal Article
Khalaf, A., Hoad, C., Menys, A., Nowak, A., Taylor, S. A., Paparo, S., Lingaya, M., Falcone, Y., Singh, G., Spiller, R. C., Gowland, P. A., Marciani, L., & Moran, G. W. (2018). MRI assessment of the postprandial gastrointestinal motility and peptide response in healthy humans. Neurogastroenterology and Motility, 30(1), Article e13182. https://doi.org/10.1111/nmo.13182

Background: Feeding triggers inter-related gastrointestinal (GI) motor, peptide and appetite responses. These are rarely studied together due to methodological limitations. Recent MRI advances allow pan-intestinal, non-invasive assessment of motility... Read More about MRI assessment of the postprandial gastrointestinal motility and peptide response in healthy humans.

Decoding fMRI events in sensorimotor motor network using sparse paradigm free mapping and activation likelihood estimates: Decoding fMRI Events in SMN (2017)
Journal Article
Tan, F. M., Caballero-Gaudes, C., Mullinger, K. J., Cho, S.-Y., Zhang, Y., Dryden, I. L., Francis, S. T., & Gowland, P. A. (2017). Decoding fMRI events in sensorimotor motor network using sparse paradigm free mapping and activation likelihood estimates: Decoding fMRI Events in SMN. Human Brain Mapping, 38(11), 5778-5794. https://doi.org/10.1002/hbm.23767

Most functional MRI (fMRI) studies map task-driven brain activity using a block or event-related paradigm. Sparse paradigm free mapping (SPFM) can detect the onset and spatial distribution of BOLD events in the brain without prior timing information,... Read More about Decoding fMRI events in sensorimotor motor network using sparse paradigm free mapping and activation likelihood estimates: Decoding fMRI Events in SMN.

A mean field model for movement induced changes in the beta rhythm (2017)
Journal Article
Byrne, Á., Brookes, M. J., & Coombes, S. (2017). A mean field model for movement induced changes in the beta rhythm. Journal of Computational Neuroscience, 43(2), https://doi.org/10.1007/s10827-017-0655-7

In electrophysiological recordings of the brain, the transition from high amplitude to low amplitude signals are most likely caused by a change in the synchrony of underlying neuronal population firing patterns. Classic examples of such modulations... Read More about A mean field model for movement induced changes in the beta rhythm.

The heritability of multi-modal connectivity in human brain activity (2017)
Journal Article
Colclough, G. L., Smith, S. M., Nichols, T. E., Winkler, A. M., Sotiropoulos, S. N., Glasser, M. F., Van Essen, D. C., & Woolrich, M. W. (in press). The heritability of multi-modal connectivity in human brain activity. eLife, 6, Article e20178. https://doi.org/10.7554/eLife.20178

Patterns of intrinsic human brain activity exhibit a profile of functional connectivity that is associated with behaviour and cognitive performance, and deteriorates with disease. This paper investigates the relative importance of genetic factors and... Read More about The heritability of multi-modal connectivity in human brain activity.