Outputs (8)

Deuterium brain imaging at 7T during D2O dosing (2022)
Journal Article
Cocking, D., Damion, R. A., Franks, H., Jaconelli, M., Wilkinson, D., Brook, M., Auer, D. P., & Bowtell, R. (2023). Deuterium brain imaging at 7T during D2O dosing. Magnetic Resonance in Medicine, 89(4), 1514-1521. https://doi.org/10.1002/mrm.29539

Purpose
To characterize the (2H) deuterium MR signal measured from human brain at 7T in participants loading with D2O to ˜1.5% enrichment over a six-week period.

Methods
2H spectroscopy and imaging measurements were used to track the time-course... Read More about Deuterium brain imaging at 7T during D2O dosing.

Improved Dynamic Contrast-Enhanced MRI Using Low Rank with Joint Sparsity (2022)
Journal Article
Zhang, J., Najeeb, F., Wang, X., Xu, P., Omer, H., Zheng, J., Zhang, J., Francis, S., Glover, P., Bowtell, R., & Wang, C. (2022). Improved Dynamic Contrast-Enhanced MRI Using Low Rank with Joint Sparsity. IEEE Access, 10, 121193-121203. https://doi.org/10.1109/access.2022.3222313

This work presents a free-breathing dynamic contrast-enhanced (DCE) MRI reconstruction method called low-rank plus sparse (L+S) with joint sparsity. The proposed method improved dynamic contrast performance by integrating an additional temporal Fast... Read More about Improved Dynamic Contrast-Enhanced MRI Using Low Rank with Joint Sparsity.

A lightweight magnetically shielded room with active shielding (2022)
Journal Article
Holmes, N., Rea, M., Chalmers, J., Leggett, J., Edwards, L. J., Nell, P., Pink, S., Patel, P., Wood, J., Murby, N., Woolger, D., Dawson, E., Mariani, C., Tierney, T. M., Mellor, S., O’Neill, G. C., Boto, E., Hill, R. M., Shah, V., Osborne, J., …Bowtell, R. (2022). A lightweight magnetically shielded room with active shielding. Scientific Reports, 12, Article 13561. https://doi.org/10.1038/s41598-022-17346-1

Magnetically shielded rooms (MSRs) use multiple layers of materials such as MuMetal to screen external magnetic fields that would otherwise interfere with high precision magnetic field measurements such as magnetoencephalography (MEG). Optically pump... Read More about A lightweight magnetically shielded room with active shielding.

A global survey of healthcare professionals undertaking MRI of patients with cochlear implants: a heterogeneity of practice and opinions (2022)
Journal Article
Dewey, R. S., Bowtell, R., & Kitterick, P. (2022). A global survey of healthcare professionals undertaking MRI of patients with cochlear implants: a heterogeneity of practice and opinions. British Journal of Radiology, 95(1137), Article 20220213. https://doi.org/10.1259/bjr.20220213

Objective: To capture practice and opinions around the current clinical use of MRI in patients with cochlear implants (CIs), and to characterise patient progression from referral to image reporting. Methods: An online survey recruited 237 healthcare... Read More about A global survey of healthcare professionals undertaking MRI of patients with cochlear implants: a heterogeneity of practice and opinions.

Phenotypic and genetic associations of quantitative magnetic susceptibility in UK Biobank brain imaging (2022)
Journal Article
Wang, C., Martins-Bach, A. B., Alfaro-Almagro, F., Douaud, G., Klein, J. C., Llera, A., Fiscone, C., Bowtell, R., Elliott, L. T., Smith, S. M., Tendler, B. C., & Miller, K. L. (2022). Phenotypic and genetic associations of quantitative magnetic susceptibility in UK Biobank brain imaging. Nature Neuroscience, 25(6), 818-831. https://doi.org/10.1038/s41593-022-01074-w

A key aim in epidemiological neuroscience is identification of markers to assess brain health and monitor therapeutic interventions. Quantitative susceptibility mapping (QSM) is an emerging magnetic resonance imaging technique that measures tissue ma... Read More about Phenotypic and genetic associations of quantitative magnetic susceptibility in UK Biobank brain imaging.

Using OPM-MEG in contrasting magnetic environments (2022)
Journal Article
Hill, R. M., Devasagayam, J., Holmes, N., Boto, E., Shah, V., Osborne, J., Safar, K., Worcester, F., Mariani, C., Dawson, E., Woolger, D., Bowtell, R., Taylor, M. J., & Brookes, M. J. (2022). Using OPM-MEG in contrasting magnetic environments. NeuroImage, 253, Article 119084. https://doi.org/10.1016/j.neuroimage.2022.119084

Magnetoencephalography (MEG) has been revolutionised by optically pumped magnetometers (OPMs). “OPM-MEG” offers higher sensitivity, better spatial resolution, and lower cost than conventional instrumentation based on superconducting quantum interfere... Read More about Using OPM-MEG in contrasting magnetic environments.

Magnetic field design in a cylindrical high-permeability shield: The combination of simple building blocks and a genetic algorithm (2022)
Journal Article
Packer, M., Hobson, P. J., Davis, A., Holmes, N., Leggett, J., Glover, P., Hardwicke, N. L., Brookes, M. J., Bowtell, R., & Fromhold, T. M. (2022). Magnetic field design in a cylindrical high-permeability shield: The combination of simple building blocks and a genetic algorithm. Journal of Applied Physics, 131(9), Article 093902. https://doi.org/10.1063/5.0071986

Magnetically sensitive experiments and newly developed quantum technologies with integrated high-permeability magnetic shields require increasing control of their magnetic field environment and reductions in size, weight, power, and cost. However, ma... Read More about Magnetic field design in a cylindrical high-permeability shield: The combination of simple building blocks and a genetic algorithm.

Triaxial detection of the neuromagnetic field using optically-pumped magnetometry: feasibility and application in children (2022)
Journal Article
Boto, E., Shah, V., Hill, R. M., Rhodes, N., Osborne, J., Doyle, C., Holmes, N., Rea, M., Leggett, J., Bowtell, R., & Brookes, M. J. (2022). Triaxial detection of the neuromagnetic field using optically-pumped magnetometry: feasibility and application in children. NeuroImage, 252, Article 119027. https://doi.org/10.1016/j.neuroimage.2022.119027

Optically-pumped magnetometers (OPMs) are an established alternative to superconducting sensors for magnetoencephalography (MEG), offering significant advantages including flexibility to accommodate any head size, uniform coverage, free movement duri... Read More about Triaxial detection of the neuromagnetic field using optically-pumped magnetometry: feasibility and application in children.