Outputs (14)

Comparing magnetic resonance liver fat fraction measurements with histology in fibrosis: the difference between proton density fat fraction and tissue mass fat fraction (2022)
Journal Article
Bawden, S. J., Hoad, C., Kaye, P., Stephenson, M., Dolman, G., James, M. W., Wilkes, E., Austin, A., Guha, I. N., Francis, S., Gowland, P., & Aithal, G. P. (2023). Comparing magnetic resonance liver fat fraction measurements with histology in fibrosis: the difference between proton density fat fraction and tissue mass fat fraction. Magnetic Resonance Materials in Physics, Biology and Medicine, 36(4), 553-563. https://doi.org/10.1007/s10334-022-01052-0

Objective: Magnetic resonance spectroscopy (MRS) provides a powerful method of measuring fat fraction. However, previous studies have shown that MRS results give lower values compared with visual estimates from biopsies in fibrotic livers. This study... Read More about Comparing magnetic resonance liver fat fraction measurements with histology in fibrosis: the difference between proton density fat fraction and tissue mass fat fraction.

Anxiety onset in adolescents: a machine-learning prediction (2022)
Journal Article
Chavanne, A. V., Martinot, M.-L. P., Penttilä, J., Grimmer, Y., Conrod, P., Stringaris, A., Van Noort, B., Isensee, C., Becker, A., Banaschewski, T., Bokde, A. L., Desrivières, S., Flor, H., Grigis, A., Garavan, H., Gowland, P., Heinz, A., Brühl, R., Nees, F., Orfanos, D. P., …Consortium, I. (2022). Anxiety onset in adolescents: a machine-learning prediction. Molecular Psychiatry, https://doi.org/10.1038/s41380-022-01840-z

Recent longitudinal studies in youth have reported MRI correlates of prospective anxiety symptoms during adolescence, a vulnerable period for the onset of anxiety disorders. However, their predictive value has not been established. Individual predict... Read More about Anxiety onset in adolescents: a machine-learning prediction.

Anxiety onset in adolescents: a machine-learning prediction (2022)
Journal Article
Chavanne, A. V., Paillère Martinot, M. L., Penttilä, J., Grimmer, Y., Conrod, P., Stringaris, A., van Noort, B., Isensee, C., Becker, A., Banaschewski, T., Bokde, A. L. W., Desrivières, S., Flor, H., Grigis, A., Garavan, H., Gowland, P., Heinz, A., Brühl, R., Nees, F., Papadopoulos Orfanos, D., …IMAGEN consortium. (2022). Anxiety onset in adolescents: a machine-learning prediction. Molecular Psychiatry, https://doi.org/10.1038/s41380-022-01840-z

Recent longitudinal studies in youth have reported MRI correlates of prospective anxiety symptoms during adolescence, a vulnerable period for the onset of anxiety disorders. However, their predictive value has not been established. Individual predict... Read More about Anxiety onset in adolescents: a machine-learning prediction.

Cortical profiles of numerous psychiatric disorders and normal development share a common pattern (2022)
Journal Article
Cao, Z., Cupertino, R. B., Ottino-Gonzalez, J., Murphy, A., Pancholi, D., Juliano, A., Chaarani, B., Albaugh, M., Yuan, D., Schwab, N., Stafford, J., Goudriaan, A. E., Hutchison, K., Li, C.-S. R., Luijten, M., Groefsema, M., Momenan, R., Schmaal, L., Sinha, R., van Holst, R. J., …ENIGMA Addiction Working Group. (2022). Cortical profiles of numerous psychiatric disorders and normal development share a common pattern. Molecular Psychiatry, https://doi.org/10.1038/s41380-022-01855-6

The neurobiological bases of the association between development and psychopathology remain poorly understood. Here, we identify a shared spatial pattern of cortical thickness (CT) in normative development and several psychiatric and neurological dis... Read More about Cortical profiles of numerous psychiatric disorders and normal development share a common pattern.

Dynamics of T2* and deformation in the placenta and myometrium during pre-labour contractions (2022)
Journal Article
Hutter, J., Kohli, V., Dellschaft, N., Uus, A., Story, L., Steinweg, J. K., Gowland, P., Hajnal, J. V., & Rutherford, M. A. (2022). Dynamics of T2* and deformation in the placenta and myometrium during pre-labour contractions. Scientific Reports, 12(1), Article 18542. https://doi.org/10.1038/s41598-022-22008-3

Pre-labour uterine contractions, occurring throughout pregnancy, are an important phenomenon involving the placenta in addition to the myometrium. They alter the uterine environment and thus potentially the blood supply to the fetus and may thus prov... Read More about Dynamics of T2* and deformation in the placenta and myometrium during pre-labour contractions.

Psychotic Like Experiences in Healthy Adolescents are Underpinned by Lower Fronto-Temporal Cortical Gyrification: a Study from the IMAGEN Consortium (2022)
Journal Article
Maitra, R., Horne, C. M., O'Daly, O., Papanastasiou, E., Gaser, C., Banaschewski, T., Barker, G. J., Bokde, A. L., Desrivières, S., Flor, H., Grigis, A., Garavan, H., Gowland, P., Heinz, A., Brühl, R., Martinot, J. L., Martinot, M. L. P., Artiges, E., Nees, F., Orfanos, D. P., …IMAGEN Consortium. (2023). Psychotic Like Experiences in Healthy Adolescents are Underpinned by Lower Fronto-Temporal Cortical Gyrification: a Study from the IMAGEN Consortium. Schizophrenia Bulletin, 49(2), 309-318. https://doi.org/10.1093/schbul/sbac132

Background and Hypothesis
Psychotic Like Experiences (PLEs) are widely prevalent in children and adolescents and increase the risk of developing psychosis. Cortical gyrification characterizes brain development from in utero till about the first 2 ye... Read More about Psychotic Like Experiences in Healthy Adolescents are Underpinned by Lower Fronto-Temporal Cortical Gyrification: a Study from the IMAGEN Consortium.

A causal association of ANKRD37 with human hippocampal volume (2022)
Journal Article
Xu, J., Xia, X., Li, Q., Dou, Y., Suo, X., Liu, N., Han, Y., Sun, X., He, Y., Qin, W., Zhang, S., Banaschewski, T., Flor, H., Grigis, A., Gowland, P., Heinz, A., Brühl, R., Martinot, J. L., Artiges, E., Nees, F., …Consortium, I. (2022). A causal association of ANKRD37 with human hippocampal volume. Molecular Psychiatry, 27, 4432-4445. https://doi.org/10.1038/s41380-022-01800-7

Human hippocampal volume has been separately associated with single nucleotide polymorphisms (SNPs), DNA methylation and gene expression, but their causal relationships remain largely unknown. Here, we aimed at identifying the causal relationships of... Read More about A causal association of ANKRD37 with human hippocampal volume.

Assessing General Versus Specific Liability for Externalizing Problems in Adolescence: Concurrent and Prospective Prediction of Symptoms of Conduct Disorder, ADHD, and Substance Use (2022)
Journal Article
Perkins, E. R., Joyner, K. J., Foell, J., Drislane, L. E., Brislin, S. J., Frick, P. J., Yancey, J. R., Soto, E. F., Ganley, C. M., Keel, P. K., Sica, C., Flor, H., Nees, F., Banaschewski, T., Bokde, A. L. W., Quinlan, E. B., Desrivières, S., Grigis, A., Garavan, H., Gowland, P., …Consortium, T. I. (2022). Assessing General Versus Specific Liability for Externalizing Problems in Adolescence: Concurrent and Prospective Prediction of Symptoms of Conduct Disorder, ADHD, and Substance Use. Journal of Psychopathology and Clinical Science, 131(7), 793-807. https://doi.org/10.1037/abn0000743

This study explored the generality versus specificity of two trait-liability factors for externalizing problems — disinhibition and callousness — in the concurrent and prospective prediction of symptoms of conduct disorder, attention-deficit/hyperact... Read More about Assessing General Versus Specific Liability for Externalizing Problems in Adolescence: Concurrent and Prospective Prediction of Symptoms of Conduct Disorder, ADHD, and Substance Use.

Global and Regional Structural Differences and Prediction of Autistic Traits during Adolescence (2022)
Journal Article
Nees, F., Banaschewski, T., Bokde, A. L. W., Desrivières, S., Grigis, A., Garavan, H., Gowland, P., Grimmer, Y., Heinz, A., Brühl, R., Isensee, C., Becker, A., Martinot, J. L., Paillère Martinot, M. L., Artiges, E., Papadopoulos Orfanos, D., Lemaître, H., Stringaris, A., van Noort, B., Paus, T., …on behalf of the IMAGEN Consortium. (2022). Global and Regional Structural Differences and Prediction of Autistic Traits during Adolescence. Brain Sciences, 12(9), Article 1187. https://doi.org/10.3390/brainsci12091187

Background: Autistic traits are commonly viewed as dimensional in nature, and as continuously distributed in the general population. In this respect, the identification of predictive values of markers such as subtle autism-related alterations in brai... Read More about Global and Regional Structural Differences and Prediction of Autistic Traits during Adolescence.

Swallow Tail Sign: Revisited (2022)
Journal Article
Brammerloh, M., Kirilina, E., Alkemade, A., Bazin, P.-L., Jantzen, C., Jäger, C., Herrler, A., Pine, K. J., Gowland, P. A., Morawski, M., Forstmann, B. U., & Weiskopf, N. (2022). Swallow Tail Sign: Revisited. Radiology, 305(3), 674-677. https://doi.org/10.1148/radiol.212696

The loss of the radiologic swallow tail sign on MRI scans of the substantia nigra is a promising diagnostic marker of Parkinson disease (1), although its anatom-ic underpinning is unclear. An early influential study showed th... Read More about Swallow Tail Sign: Revisited.