Outputs (7)

CHAPTER 8: Solid-state NMR in the Study of Intermolecular Interactions (2018)
Book Chapter
Rossi, F., Cerreia Vioglio, P., Chierotti, M. R., & Gobetto, R. (2018). CHAPTER 8: Solid-state NMR in the Study of Intermolecular Interactions. In Understanding Intermolecular Interactions in the Solid State (243-284). Royal Society of Chemistry. https://doi.org/10.1039/9781788013086-00243

Solid-state NMR (SSNMR) techniques yield a wealth of information complementary to, or alternative to, X-ray crystallography, thus providing similar yet different insights into the investigation of supramolecular systems. Indeed, SSNMR parameters can... Read More about CHAPTER 8: Solid-state NMR in the Study of Intermolecular Interactions.

New substituted imidazo[1,5-a]pyridine and imidazo[5,1-a]isoquinoline derivatives and their application in fluorescence cell imaging (2018)
Journal Article
Volpi, G., Lace, B., Garino, C., Priola, E., Artuso, E., Cerreia Vioglio, P., Barolo, C., Fin, A., Genre, A., & Prandi, C. (2018). New substituted imidazo[1,5-a]pyridine and imidazo[5,1-a]isoquinoline derivatives and their application in fluorescence cell imaging. Dyes and Pigments, 157, 298-304. https://doi.org/10.1016/j.dyepig.2018.04.037

A series of new dyes based on the fluorescent imidazo[1,5-a]pyridine moiety has been designed and synthesized specifically for fluorescence cell imaging application. The obtained molecules contain a carboxylic functional group inserted to increase th... Read More about New substituted imidazo[1,5-a]pyridine and imidazo[5,1-a]isoquinoline derivatives and their application in fluorescence cell imaging.

79/81Br nuclear quadrupole resonance spectroscopic characterization of halogen bonds in supramolecular assemblies (2018)
Journal Article
Cerreia Vioglio, P., Szell, P. M., Chierotti, M. R., Gobetto, R., & Bryce, D. L. (2018). 79/81Br nuclear quadrupole resonance spectroscopic characterization of halogen bonds in supramolecular assemblies. Chemical Science, 9(20), 4555-4561. https://doi.org/10.1039/c8sc01094c

Despite the applicability of solid-state NMR to study the halogen bond, the direct NMR detection of 79/81Br covalently bonded to carbon remains impractical due to extremely large spectral widths, even at ultra-high magnetic fields. In contrast, nucle... Read More about 79/81Br nuclear quadrupole resonance spectroscopic characterization of halogen bonds in supramolecular assemblies.

Insights into the Crystallization and Structural Evolution of Glycine Dihydrate by In Situ Solid-State NMR Spectroscopy (2018)
Journal Article
Cerreia Vioglio, P., Mollica, G., Juramy, M., E. Hughes, C., Andrew Williams, P., Ziarelli, F., Viel, S., Thureau, P., & D. M. Harris, K. (2018). Insights into the Crystallization and Structural Evolution of Glycine Dihydrate by In Situ Solid-State NMR Spectroscopy. Angewandte Chemie, 130(22), 6729-6733. https://doi.org/10.1002/ange.201801114

In situ solid-state NMR spectroscopy is exploited to monitor the structural evolution of a glycine/water glass phase formed on flash cooling an aqueous solution of glycine, with a range of modern solid-state NMR methods applied to elucidate structura... Read More about Insights into the Crystallization and Structural Evolution of Glycine Dihydrate by In Situ Solid-State NMR Spectroscopy.

Insights into the Crystallization and Structural Evolution of Glycine Dihydrate by In Situ Solid-State NMR Spectroscopy (2018)
Journal Article
Cerreia Vioglio, P., Mollica, G., Juramy, M., E. Hughes, C., Andrew Williams, P., Ziarelli, F., Viel, S., Thureau, P., & D. M. Harris, K. (2018). Insights into the Crystallization and Structural Evolution of Glycine Dihydrate by In Situ Solid-State NMR Spectroscopy. Angewandte Chemie International Edition, 57(22), 6619-6623. https://doi.org/10.1002/anie.201801114

In situ solid-state NMR spectroscopy is exploited to monitor the structural evolution of a glycine/water glass phase formed on flash cooling an aqueous solution of glycine, with a range of modern solid-state NMR methods applied to elucidate structura... Read More about Insights into the Crystallization and Structural Evolution of Glycine Dihydrate by In Situ Solid-State NMR Spectroscopy.

Unraveling the Hydrogen Bond Network in a Theophylline–Pyridoxine Salt Cocrystal by a Combined X-ray Diffraction, Solid-State NMR, and Computational Approach (2018)
Journal Article
Rossi, F., Cerreia Vioglio, P., Bordignon, S., Giorgio, V., Nervi, C., Priola, E., Gobetto, R., Yazawa, K., & Chierotti, M. R. (2018). Unraveling the Hydrogen Bond Network in a Theophylline–Pyridoxine Salt Cocrystal by a Combined X-ray Diffraction, Solid-State NMR, and Computational Approach. Crystal Growth and Design, 18(4), 2225-2233. https://doi.org/10.1021/acs.cgd.7b01662

The formation of a codrug, a cocrystal formed by two active pharmaceutical ingredients (APIs), between theophylline (THEO) and pyridoxine·HCl (PyrH+Cl–) is reported. The THEO PyrH+Cl– drug–drug cocrystal could turn out to be interesting in the pharma... Read More about Unraveling the Hydrogen Bond Network in a Theophylline–Pyridoxine Salt Cocrystal by a Combined X-ray Diffraction, Solid-State NMR, and Computational Approach.

A new soluble and bioactive polymorph of praziquantel (2018)
Journal Article
Zanolla, D., Perissutti, B., Passerini, N., Chierotti, M. R., Hasa, D., Voinovich, D., Gigli, L., Demitri, N., Geremia, S., Keiser, J., Cerreia Vioglio, P., & Albertini, B. (2018). A new soluble and bioactive polymorph of praziquantel. European Journal of Pharmaceutics and Biopharmaceutics, 127, 19-28. https://doi.org/10.1016/j.ejpb.2018.01.018

Praziquantel is the only available drug to treat Schistosomiasis. However, its utilization is limited by many drawbacks, including the high therapeutic dose needed, resulting in large tablets and capsules difficult to be swallowed, especially from pe... Read More about A new soluble and bioactive polymorph of praziquantel.