Outputs (112)

PolySTRAND Model of Flow-Induced Nucleation in Polymers (2020)
Journal Article
Read, D. J., McIlroy, C., Das, C., Harlen, O. G., & Graham, R. S. (2020). PolySTRAND Model of Flow-Induced Nucleation in Polymers. Physical Review Letters, 124(14), Article 147802. https://doi.org/10.1103/physrevlett.124.147802

We develop a thermodynamic continuum-level model, polySTRAND, for flow-induced nucleation in polymers suitable for use in computational process modeling. The model's molecular origins ensure that it accounts properly for flow and nucleation dynamics... Read More about PolySTRAND Model of Flow-Induced Nucleation in Polymers.

Corrigendum to “A systematic strategy for estimating hERG block potency and its implications in a new cardiac safety paradigm” [Toxicology and Applied Pharmacology volume 394C (2020) 114961] (2020)
Journal Article
Ridder, B. J., Leishman, D. J., Bridgland-Taylor, M., Samieegohar, M., Han, X., Wu, W. W., Randolph, A., Tran, P., Sheng, J., Danker, T., Lindqvist, A., Konrad, D., Hebeisen, S., Polonchuk, L., Gissinger, E., Renganathan, M., Koci, B., Wei, H., Fan, J., Levesque, P., …Li, Z. (2020). Corrigendum to “A systematic strategy for estimating hERG block potency and its implications in a new cardiac safety paradigm” [Toxicology and Applied Pharmacology volume 394C (2020) 114961]. Toxicology and Applied Pharmacology, 395, Article 114983. https://doi.org/10.1016/j.taap.2020.114983

© 2020 The Author(s) The authors regret that one affiliation address is mistaken in the published paper. Matthew Bridgland-Taylor's affiliation was incorrectly listed as Clinical Pharmacology & Safety Sciences, R&D, AstraZeneca, Cambridge, United Kin... Read More about Corrigendum to “A systematic strategy for estimating hERG block potency and its implications in a new cardiac safety paradigm” [Toxicology and Applied Pharmacology volume 394C (2020) 114961].

Eigenvalue and eigenvector statistics in time series analysis (2020)
Journal Article
Barucca, P., Kieburg, M., & Ossipov, A. (2020). Eigenvalue and eigenvector statistics in time series analysis. EPL, 129(6), Article 60003. https://doi.org/10.1209/0295-5075/129/60003

The study of correlated time series is ubiquitous in statistical analysis, and the matrix decomposition of the cross-correlations between time series is a universal tool to extract the principal patterns of behavior in a wide range of complex systems... Read More about Eigenvalue and eigenvector statistics in time series analysis.

Regression modelling for size-and-shape data based on a Gaussian model for landmarks (2020)
Journal Article
Dryden, I. L., Kume, A., Paine, P. J., & Wood, A. T. A. (2021). Regression modelling for size-and-shape data based on a Gaussian model for landmarks. Journal of the American Statistical Association, 116(534), 1011-1022. https://doi.org/10.1080/01621459.2020.1724115

In this paper we propose a regression model for size-and-shape response data. So far as we are aware, few such models have been explored in the literature to date. We assume a Gaussian model for labelled landmarks; these landmarks are used to represe... Read More about Regression modelling for size-and-shape data based on a Gaussian model for landmarks.

A systematic strategy for estimating hERG block potency and its implications in a new cardiac safety paradigm (2020)
Journal Article
Bardenet, R., Ridder, B. J., Leishman, D. J., Bridgland-Taylor, M., Samieegohar, M., Han, X., Wu, W. W., Randolph, A., Tran, P., Sheng, J., Danker, T., Lindqvist, A., Konrad, D., Hebeisen, S., Polonchuk, L., Gissinger, E., Renganathan, M., Koci, B., Wei, H., Fan, J., …Li, Z. (2020). A systematic strategy for estimating hERG block potency and its implications in a new cardiac safety paradigm. Toxicology and Applied Pharmacology, 394, Article 114961. https://doi.org/10.1016/j.taap.2020.114961

© 2020 Introduction: hERG block potency is widely used to calculate a drug's safety margin against its torsadogenic potential. Previous studies are confounded by use of different patch clamp electrophysiology protocols and a lack of statistical quant... Read More about A systematic strategy for estimating hERG block potency and its implications in a new cardiac safety paradigm.

Regularity of R(X) does not pass to finite unions (2020)
Journal Article
Feinstein, J. F. (2020). Regularity of R(X) does not pass to finite unions. Proceedings of the American Mathematical Society, 148(7), 2931-2936. https://doi.org/10.1090/proc/14944

We show that there are compact plane sets X, Y such that R(X) and R(Y) are regular but R(X ∪ Y) is not regular.

Speed Switch in Glioblastoma Growth Rate due to Enhanced Hypoxia-Induced Migration (2020)
Journal Article
Curtin, L., Hawkins-Daarud, A., van der Zee, K. G., Swanson, K. R., & Owen, M. R. (2020). Speed Switch in Glioblastoma Growth Rate due to Enhanced Hypoxia-Induced Migration. Bulletin of Mathematical Biology, 82(3), Article 43. https://doi.org/10.1007/s11538-020-00718-x

We analyze the wave-speed of the Proliferation Invasion Hypoxia Necro-sis Angiogenesis (PIHNA) model that was previously created and applied to simulate the growth and spread of glioblastoma (GBM), a particularly aggressive primary brain tumor. We ex... Read More about Speed Switch in Glioblastoma Growth Rate due to Enhanced Hypoxia-Induced Migration.

Microwave Realization of the Chiral Orthogonal, Unitary, and Symplectic Ensembles (2020)
Journal Article
Rehemanjiang, A., Richter, M., Kuhl, U., & Stöckmann, H.-J. (2020). Microwave Realization of the Chiral Orthogonal, Unitary, and Symplectic Ensembles. Physical Review Letters, 124(11), Article 116801. https://doi.org/10.1103/physrevlett.124.116801

Random matrix theory has proven very successful in the understanding of the spectra of chaotic systems. Depending on symmetry with respect to time reversal and the presence or absence of a spin 1/2 there are three ensembles, the Gaussian orthogonal (... Read More about Microwave Realization of the Chiral Orthogonal, Unitary, and Symplectic Ensembles.

Chaste: Cancer, Heart and Soft Tissue Environment (2020)
Journal Article
Cooper, F., Baker, R., Bernabeu, M., Bordas, R., Bowler, L., Bueno-Orovio, A., Byrne, H., Carapella, V., Cardone-Noott, L., Cooper, J., Dutta, S., Evans, B., Fletcher, A., Grogan, J., Guo, W., Harvey, D., Hendrix, M., Kay, D., Kursawe, J., Maini, P., …Gavaghan, D. (2020). Chaste: Cancer, Heart and Soft Tissue Environment. Journal of Open Source Software, 5(47), Article 1848. https://doi.org/10.21105/joss.01848

Understanding microwave heating in biomass-solvent systems (2020)
Journal Article
Taqi, A., Farcot, E., Robinson, J. P., & Binner, E. R. (2020). Understanding microwave heating in biomass-solvent systems. Chemical Engineering Journal, 393, Article 124741. https://doi.org/10.1016/j.cej.2020.124741

A new mechanism is proposed to provide a viable physical explanation for the action of microwaves in solvent extraction processes. The key innovation is Temperature-Induced Diffusion, a recently-demonstrated phenomenon that results from selective hea... Read More about Understanding microwave heating in biomass-solvent systems.