Outputs (158)

Factor XII and kininogen asymmetric assembly with gC1qR/C1QBP/P32 is governed by allostery (2020)
Journal Article
Kaira, B. G., Slater, A., McCrae, K. R., Dreveny, I., Sumya, U.-M., Mutch, N. J., Searle, M., & Emsley, J. (2020). Factor XII and kininogen asymmetric assembly with gC1qR/C1QBP/P32 is governed by allostery. Blood, 136(14), 1685–1697. https://doi.org/10.1182/blood.2020004818

The contact system is composed of Factor XII (FXII), prekallikrein (PK) and co-factor kininogen (HK). The globular C1q receptor (gC1qR) has been shown to interact with FXII and HK. We reveal the FXII fibronectin type II domain (FnII) binds gC1qR in a... Read More about Factor XII and kininogen asymmetric assembly with gC1qR/C1QBP/P32 is governed by allostery.

Carbene‐induced rescue of catalytic activity in deactivated Nitrite Reductase mutant (2020)
Journal Article
Planchestainer, M., Schulz, C., McMaster, J., Paradisi, F., & Albrecht, M. (2020). Carbene‐induced rescue of catalytic activity in deactivated Nitrite Reductase mutant. Chemistry - A European Journal, 26(66), 15206-15211. https://doi.org/10.1002/chem.202002444

The role of His145 in the T1 copper center of Nitrite Reductase (NiR) is pivotal for the activity of the enzyme. Mutation to a glycine at this position enables the reconstitution of the T1 center by the addition of imidazole as exogenous ligands, how... Read More about Carbene‐induced rescue of catalytic activity in deactivated Nitrite Reductase mutant.

Möbius and Hückel Cyclacenes with Dewar and Ladenburg Defects (2020)
Journal Article
Hanson-Heine, M. W., & Hirst, J. D. (2020). Möbius and Hückel Cyclacenes with Dewar and Ladenburg Defects. Journal of Physical Chemistry A, 124(26), 5408-5414. https://doi.org/10.1021/acs.jpca.0c04137

Copyright © 2020 American Chemical Society. Cyclacene nanobelts have not been synthesized in over 60 years and remain one of the last unsynthesized building blocks of carbon nanotubes. Recent work has predicted that Hückel-cyclacenes containing Dewar... Read More about Möbius and Hückel Cyclacenes with Dewar and Ladenburg Defects.

A transition metal–gallium cluster formed via insertion of “GaI” (2020)
Journal Article
Blundell, T. J., Taylor, L. J., Valentine, A. J., Lewis, W., Blake, A. J., McMaster, J., & Kays, D. L. (2020). A transition metal–gallium cluster formed via insertion of “GaI”. Chemical Communications, 56(58), 8139-8142. https://doi.org/10.1039/d0cc03559a

The reaction between a two-coordinate Co(II) diaryl complex and “GaI” affords 2,6-Pmp2C6H3CoGa3I5, in a new geometry for a heavier group 13-transition metal cluster. Experimental and computational investigations show that this compound is best descri... Read More about A transition metal–gallium cluster formed via insertion of “GaI”.

Transition metal decorated soft nanomaterials through modular self-assembly of an asymmetric hybrid polyoxometalate (2020)
Journal Article
Hampson, E., Cameron, J. M., Watts, J. A., & Newton, G. N. (2020). Transition metal decorated soft nanomaterials through modular self-assembly of an asymmetric hybrid polyoxometalate. Chemical Communications, 56, 8237-8240. https://doi.org/10.1039/d0cc03554h

An asymmetrically functionalised Wells–Dawson organic–inorganic hybrid polyoxometalate has been post-functionalised by Pt2+ coordination, and demonstrates self-assembly into surface-decorated micellar nanostructures. This multifunctional hybrid mater... Read More about Transition metal decorated soft nanomaterials through modular self-assembly of an asymmetric hybrid polyoxometalate.

Development of a Corynebacterium glutamicum bio-factory for self-sufficient transaminase reactions (2020)
Journal Article
Grigoriou, S., Kugler, P., Kulcinskaja, E., Walter, F., King, J., Hill, P., Wendisch, V. F., & O'Reilly, E. (2020). Development of a Corynebacterium glutamicum bio-factory for self-sufficient transaminase reactions. Green Chemistry, 22(13), 4128-4132. https://doi.org/10.1039/d0gc01432j

The development of biocatalytic routes for the synthesis of chiral amines starting from achiral building blocks is highly desirable. Here, we report a self-sufficient whole-cell system for the conversion of a model ketone to the corresponding cyclic... Read More about Development of a Corynebacterium glutamicum bio-factory for self-sufficient transaminase reactions.

On-surface chemical reactions characterised by ultra-high resolution scanning probe microscopy (2020)
Journal Article
Sweetman, A., Champness, N. R., & Saywell, A. (2020). On-surface chemical reactions characterised by ultra-high resolution scanning probe microscopy. Chemical Society Reviews, 49(13), 4189-4202. https://doi.org/10.1039/d0cs00166j

In the last decade it has become possible to resolve the geometric structure of organic molecules with intramolecular resolution using high resolution scanning probe microscopy (SPM), and specifically using the subset of SPM known as noncontact atomi... Read More about On-surface chemical reactions characterised by ultra-high resolution scanning probe microscopy.

Thermally-Stable Imidazolium Dicationic Ionic Liquids with Pyridine Functional Groups (2020)
Journal Article
Clarke, C. J., Bui-Le, L., Hallett, J. P., & Licence, P. (2020). Thermally-Stable Imidazolium Dicationic Ionic Liquids with Pyridine Functional Groups. ACS Sustainable Chemistry and Engineering, 8(23), 8762-8772. https://doi.org/10.1021/acssuschemeng.0c02473

Thermally-stable ionic liquids (ILs) have limited structural possibilities and lack coordinating anions or functional groups. Thermal stability effectively incurs a tunability penalty, limiting ionic liquid function to render them as simple heat-stab... Read More about Thermally-Stable Imidazolium Dicationic Ionic Liquids with Pyridine Functional Groups.

Variations in Duschinsky rotations in m-fluorotoluene and m-chlorotoluene during excitation and ionization (2020)
Journal Article
Davies, A. R., Kemp, D. J., Warner, L. G., Fryer, E. F., Rees, A., & Wright, T. G. (2020). Variations in Duschinsky rotations in m-fluorotoluene and m-chlorotoluene during excitation and ionization. Journal of Chemical Physics, 152(21), Article 214303. https://doi.org/10.1063/5.0009391

We investigate Duschinsky rotation/mixing between three vibrations for both m-fluorotoluene (mFT) and m-chlorotoluene (mClT), during electronic excitation and ionization. In the case of mFT, we investigate both the S1 → S0 electronic transition and t... Read More about Variations in Duschinsky rotations in m-fluorotoluene and m-chlorotoluene during excitation and ionization.

Neoproterozoic Nafun Group Sediments from Oman Affected by an Active Continental Margin (2020)
Journal Article
Yue, L., & Vandeginste, V. (2020). Neoproterozoic Nafun Group Sediments from Oman Affected by an Active Continental Margin. Minerals, 10(6), Article 511. https://doi.org/10.3390/min10060511

The Neoproterozoic era is a time of major environmental change in Earth history. The Ediacaran period (635–541 Ma), the uppermost division of Precambrian time, is characterized by the remarkable Shuram excursion (largest C isotope negative excursion)... Read More about Neoproterozoic Nafun Group Sediments from Oman Affected by an Active Continental Margin.