Outputs (3)

A paper-based in vitro model for on-chip investigation of the human respiratory system (2016)
Journal Article
Rahimi, R., Htwe, S. S., Ochoa, M., Donaldson, A., Zieger, M., Sood, R., Tamayol, A., Khademhosseini, A., Ghaemmaghami, A. M., & Ziaie, B. (in press). A paper-based in vitro model for on-chip investigation of the human respiratory system. Lab on a Chip, 16(22), https://doi.org/10.1039/C6LC00866F

Culturing cells at the air–liquid interface (ALI) is essential for creating functional in vitro models of lung tissues. We present the use of direct-patterned laser-treated hydrophobic paper as an effective semi-permeable membrane, ideal for ALI cell... Read More about A paper-based in vitro model for on-chip investigation of the human respiratory system.

Effective antigen presentation to helper T cells by human eosinophils (2016)
Journal Article
Farhan, R. K., Vickers, M. A., Ghaemmaghami, A. M., Hall, A. M., Barker, R. N., & Walsh, G. M. (in press). Effective antigen presentation to helper T cells by human eosinophils. Immunology, https://doi.org/10.1111/imm.12658

Although eosinophils are inflammatory cells, there is increasing attention on their immunomodulatory roles. For example, murine eosinophils can present antigen to CD4+ T helper (Th) cells, but it remains unclear whether human eosinophils also have th... Read More about Effective antigen presentation to helper T cells by human eosinophils.

Immunomodulation with self-crosslinked polyelectrolyte multilayer-based coatings (2016)
Journal Article
Knopf-Marques, H., Singh, S., Htwe, S. S., Wolfova, L., Buffa, R., Bacharouche, J., Francius, G., Voegel, J.-C., Schaaf, P., Ghaemmaghami, A. M., Vrana, N. E., & Lavalle, P. (2016). Immunomodulation with self-crosslinked polyelectrolyte multilayer-based coatings. Biomacromolecules, 17(6), 2189-2198. https://doi.org/10.1021/acs.biomac.6b00429

This study aims to design an optimal polyelectrolyte multilayer film of poly-L-lysine (PLL) and hyaluronic acid(HA) as an anti-inflammatory cytokine release system in order to decrease the implant failure due to any immune reactions. The chemical mod... Read More about Immunomodulation with self-crosslinked polyelectrolyte multilayer-based coatings.