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Retrospective evaluation of thoracic computed tomography findings in dogs naturally infected by Angiostrongylus vasorum (2017)
Journal Article
Coia, M. E., Hammond, G., Chan, D., Drees, R., Walker, D., Murtagh, K., …Bexfield, N. (in press). Retrospective evaluation of thoracic computed tomography findings in dogs naturally infected by Angiostrongylus vasorum. Veterinary Radiology and Ultrasound, 58(5), https://doi.org/10.1111/vru.12505

Angiostrongylus vasorum (A. vasorum) is an important emerging disease of canidae. Cardiorespiratory signs are common in affected dogs, therefore thoracic imaging is critical for diagnosing andmonitoring disease. Descriptions of thoracic computed tomo... Read More about Retrospective evaluation of thoracic computed tomography findings in dogs naturally infected by Angiostrongylus vasorum.

"She's a dog at the end of the day": guide dog owners' perspectives on the behaviour of their guide dog (2017)
Journal Article
Craigon, P. J., Hobson-West, P., England, G. C., Whelan, C. T., Lethbridge, E., & Asher, L. (2017). "She's a dog at the end of the day": guide dog owners' perspectives on the behaviour of their guide dog. PLoS ONE, 12(4), Article e0176018. https://doi.org/10.1371/journal.pone.0176018

A guide dog is a domestic dog (Canis familiaris) that is specifically educated to provide mobility support to a blind or visually impaired owner. Current dog suitability assessments focus on behavioural traits, including: trainability, reactivity or... Read More about "She's a dog at the end of the day": guide dog owners' perspectives on the behaviour of their guide dog.

Unbiased analysis of the impact of micropatterned biomaterials on macrophage behaviour provides insights beyond pre-defined polarisation states (2017)
Journal Article
Singh, S., Awuah, D., Rostam, H., Emes, R., Kandola, N. K., Onion, D., …Ghaemmaghami, A. M. (in press). Unbiased analysis of the impact of micropatterned biomaterials on macrophage behaviour provides insights beyond pre-defined polarisation states. ACS Biomaterials Science and Engineering, https://doi.org/10.1021/acsbiomaterials.7b00104

Macrophages are master regulators of immune responses towards implanted biomaterials. The activation state adopted by macrophages in response to biomaterials determines their own phenotype and function as well as those of other resident and infiltrat... Read More about Unbiased analysis of the impact of micropatterned biomaterials on macrophage behaviour provides insights beyond pre-defined polarisation states.

Mathematical modeling of ovine footrot in the UK: the effect of Dichelobacter nodosus and Fusobacterium necrophorum on the disease dynamics (2017)
Journal Article
Atia, J., Monaghan, E., Kaler, J., Purdy, K., Green, L., & Keeling, M. (in press). Mathematical modeling of ovine footrot in the UK: the effect of Dichelobacter nodosus and Fusobacterium necrophorum on the disease dynamics. Epidemics, 21, 13-20. https://doi.org/10.1016/j.epidem.2017.04.001

Dichelobacter nodosus is a virulent, invasive, anaerobic bacterium that is believed to be the causative agent of ovine footrot, an infectious bacterial disease of sheep that causes lameness. Another anaerobe, Fusobacterium necrophorum, has been intim... Read More about Mathematical modeling of ovine footrot in the UK: the effect of Dichelobacter nodosus and Fusobacterium necrophorum on the disease dynamics.

Can farmers reliably perform neonatal lamb post mortems and what are the perceived obstacles to influencing lamb mortality? (2017)
Journal Article
Gascoigne, E., Bazeley, K., & Lovatt, F. (2017). Can farmers reliably perform neonatal lamb post mortems and what are the perceived obstacles to influencing lamb mortality?. Small Ruminant Research, 151, https://doi.org/10.1016/j.smallrumres.2017.03.017

Neonatal lamb mortality constitutes a significant economic cost and is an important welfare challenge. Despite compelling evidence for reduction strategies and cost benefits associated with them, there has been no documented reduction in mortality si... Read More about Can farmers reliably perform neonatal lamb post mortems and what are the perceived obstacles to influencing lamb mortality?.

Neuroaxonal dystrophy in a flock of pied imperial pigeons (Ducula bicolor) (2017)
Journal Article
Barrows, M., Killick, R., Day, C., Saunders, R., Baiker, K., Ressel, L., & Denk, D. (2017). Neuroaxonal dystrophy in a flock of pied imperial pigeons (Ducula bicolor). Journal of Comparative Pathology, 156(4), 451-457. https://doi.org/10.1016/j.jcpa.2017.02.006

Five juvenile pied imperial pigeons (Ducula bicolor) presented with neurological signs including torticollis, ataxia and poor flying ability. All were humanely destroyed and submitted for post-mortem examination. Microscopically, the most significant... Read More about Neuroaxonal dystrophy in a flock of pied imperial pigeons (Ducula bicolor).

A multi-national European cross-sectional study of feline calicivirus epidemiology, diversity and vaccine cross-reactivity (2017)
Journal Article
Afonso, M. M., Pinchbeck, G. L., Smith, S. L., Daly, J. M., Gaskell, R. M., Dawson, S., & Radford, A. D. (2017). A multi-national European cross-sectional study of feline calicivirus epidemiology, diversity and vaccine cross-reactivity. Vaccine, 35(20), 2753-2760. https://doi.org/10.1016/j.vaccine.2017.03.030

Background

Feline calicivirus (FCV) is an important pathogen of cats for which vaccination is regularly practised. Long-term use of established vaccine antigens raises the theoretical possibility that field viruses could become resistant. This stu... Read More about A multi-national European cross-sectional study of feline calicivirus epidemiology, diversity and vaccine cross-reactivity.

Nonselective Bottlenecks Control the Divergence and Diversification of Phase-Variable Bacterial Populations (2017)
Journal Article
Aidley, J. B., Rajopadhye, S., Akinyemi, N., Lango-Scholey, L., Jones, M. A., & Bayliss, C. D. (2017). Nonselective Bottlenecks Control the Divergence and Diversification of Phase-Variable Bacterial Populations. mBio, 8(2), 1-14. https://doi.org/10.1128/mBio.02311-16

Phase variation occurs in many pathogenic and commensal bacteria and is a major generator of genetic variability. A putative advantage of phase variation is to counter reductions in variability imposed by nonselective bottlenecks during transmission.... Read More about Nonselective Bottlenecks Control the Divergence and Diversification of Phase-Variable Bacterial Populations.

Subset-specific expression of toll-like receptors by bovine afferent lymph dendritic cells (2017)
Journal Article
Werling, D., Hope, J. C., Siddiqui, N., Widdison, S., Russell, C., Sopp, P., & Coffey, T. J. (2017). Subset-specific expression of toll-like receptors by bovine afferent lymph dendritic cells. Frontiers in Veterinary Science, 4, Article 44. https://doi.org/10.3389/fvets.2017.00044

Within the ruminant system, several possibilities exist to generate dendritic cells migrating out from the tissue into the regional draining lymph nodes as afferent lymph dendritic cells (ALDCs). Here, we analyzed toll-like receptor (TLR) 1–10 mRNA e... Read More about Subset-specific expression of toll-like receptors by bovine afferent lymph dendritic cells.