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Outputs (71)

A signature motif mediating selective interactions of BCL11A with the NR2E/F subfamily of orphan nuclear receptors (2013)
Journal Article
Chan, C. M., Fulton, J., Montiel-Duarte, C., Collins, H. M., Bharti, N., Wadelin, F. R., …Heery, D. M. (2013). A signature motif mediating selective interactions of BCL11A with the NR2E/F subfamily of orphan nuclear receptors. Nucleic Acids Research, 41(21), https://doi.org/10.1093/nar/gkt761

Despite their physiological importance, selective interactions between nuclear receptors (NRs) and their cofactors are poorly understood. Here, we describe a novel signature motif (F/YSXXLXXL/Y) in the developmental regulator BCL11A that facilitates... Read More about A signature motif mediating selective interactions of BCL11A with the NR2E/F subfamily of orphan nuclear receptors.

The educational impact of assessment: a comparison of DOPS and MCQs (2013)
Journal Article
Cobb, K. A., Brown, G., Jaarsma, D. A., & Hammond, R. A. (2013). The educational impact of assessment: a comparison of DOPS and MCQs. Medical Teacher, 35(1), Article e1598-e1607. https://doi.org/10.3109/0142159X.2013.803061

Aim: To evaluate the impact of two different assessment formats on the approaches to learning of final year veterinary students. The relationship between approach to learning and examination performance was also investigated. Method: An 18-item ve... Read More about The educational impact of assessment: a comparison of DOPS and MCQs.

A retrospective study of pyometra at five RSPCA hospitals in the United Kingdom: 1,728 cases from 2006-2011 (2013)
Journal Article
Gibson, A., Dean, R. S., Yates, D., & Stavisky, J. (2013). A retrospective study of pyometra at five RSPCA hospitals in the United Kingdom: 1,728 cases from 2006-2011. Veterinary Record, 173(16), https://doi.org/10.1136/vr.101514

A retrospective cross-sectional study was used to analyse pyometra cases at five RSPCA Animal Hospitals across the UK from 2006 to 2011. A total of 1728 cases of pyometra were recovered from a female dog outpatient caseload of 78,469 animals, giv... Read More about A retrospective study of pyometra at five RSPCA hospitals in the United Kingdom: 1,728 cases from 2006-2011.

Comparative virus replication and host innate responses in human cells infected with three prevalent clades (2.3.4, 2.3.2, and 7) of highly pathogenic avian influenza H5N1 viruses (2013)
Journal Article
Sun, H., Sun, Y., Pu, J., Zhang, Y., Zhu, Q., Li, J., …Liu, J. (2014). Comparative virus replication and host innate responses in human cells infected with three prevalent clades (2.3.4, 2.3.2, and 7) of highly pathogenic avian influenza H5N1 viruses. Journal of Virology, 88(1), https://doi.org/10.1128/JVI.02510-13

Highly pathogenic avian influenza H5N1 virus clades 2.3.4, 2.3.2, and 7 are the dominant cocirculating H5N1 viruses in poultry in China. However, humans appear to be clinically susceptible mostly to the 2.3.4 virus clade. Here, we demonstrated that A... Read More about Comparative virus replication and host innate responses in human cells infected with three prevalent clades (2.3.4, 2.3.2, and 7) of highly pathogenic avian influenza H5N1 viruses.

Association between somatic cell count after first parturition and cumulative milk yield in dairy cows (2013)
Journal Article
Archer, S. C., McCoy, F., Wapenaar, W., & Green, M. J. (2013). Association between somatic cell count after first parturition and cumulative milk yield in dairy cows. Veterinary Record, 173(13), https://doi.org/10.1136/vr.101558

The aim was to assess the association between the somatic cell count of parity 1 cows between 5 and 30 days in milk (SCC1), and subsequent cumulative milk yield over approximately two years for cows in English and Welsh dairy herds. The dataset inclu... Read More about Association between somatic cell count after first parturition and cumulative milk yield in dairy cows.

Rate of transmission: a major determinant of the cost of clinical mastitis (2013)
Journal Article
Down, P., Green, M. J., & Hudson, C. (2013). Rate of transmission: a major determinant of the cost of clinical mastitis. Journal of Dairy Science, 96(10), https://doi.org/10.3168/jds.2012-6470

The aim of this research was to use probabilistic sensitivity analysis to evaluate the relative importance of different components of a model designed to estimate the cost of clinical mastitis (CM). A particular focus was placed on the importance... Read More about Rate of transmission: a major determinant of the cost of clinical mastitis.

Sheep farmer opinions on the current and future role of veterinarians in flock health management on sheep farms: a qualitative study (2013)
Journal Article
Kaler, J., & Green, L. (2013). Sheep farmer opinions on the current and future role of veterinarians in flock health management on sheep farms: a qualitative study. Preventive Veterinary Medicine, 112(3-4), https://doi.org/10.1016/j.prevetmed.2013.09.009

A 2009 UK Government report on veterinary expertise in food animal production highlighted that there was insufficient herd health expertise among veterinarians and lack of appropriate business models to deliver veterinary services to the livestock se... Read More about Sheep farmer opinions on the current and future role of veterinarians in flock health management on sheep farms: a qualitative study.

The future of osteoarthritis therapeutics: targeted pharmacological therapy (2013)
Journal Article
Mobasheri, A. (2013). The future of osteoarthritis therapeutics: targeted pharmacological therapy. Current Rheumatology Reports, 15(10), Article 13. https://doi.org/10.1007/s11926-013-0364-9

Osteoarthritis (OA) is one of the most common forms of degenerative joint disease and a major cause of pain and disability affecting the aging population. It is estimated that more than 20 million Americans and 35 to 40 million Europeans suffer from... Read More about The future of osteoarthritis therapeutics: targeted pharmacological therapy.