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Carprofen inhibits the release of matrix metalloproteinases 1, 3, and 13 in the secretome of an explant model of articular cartilage stimulated with interleukin 1β (2013)
Journal Article
Williams, A., Smith, J. R., Allaway, D., Harris, P., Liddell, S., & Mobasheri, A. (2013). Carprofen inhibits the release of matrix metalloproteinases 1, 3, and 13 in the secretome of an explant model of articular cartilage stimulated with interleukin 1β. Arthritis Research and Therapy, 15(6), Article R223. https://doi.org/10.1186/ar4424

Introduction: Arthritic diseases are characterized by the degradation of collagenous and noncollagenous extracellular matrix (ECM) components in articular cartilage. The increased expression and activity of matrix metalloproteinases (MMPs) is partly... Read More about Carprofen inhibits the release of matrix metalloproteinases 1, 3, and 13 in the secretome of an explant model of articular cartilage stimulated with interleukin 1β.

IL-25 and type 2 innate lymphoid cells induce pulmonary fibrosis (2013)
Journal Article
Hams, E., Armstrong, M. E., Barlow, J. L., Saunders, S. P., Schwartz, C., Cooke, G., …Fallon, P. G. (2014). IL-25 and type 2 innate lymphoid cells induce pulmonary fibrosis. Proceedings of the National Academy of Sciences, 111(1), 367-372. https://doi.org/10.1073/pnas.1315854111

Disease conditions associated with pulmonary fibrosis are progressive and have a poor long-term prognosis with irreversible changes in airway architecture leading to marked morbidity and mortalities. Using murine models we demonstrate a role for inte... Read More about IL-25 and type 2 innate lymphoid cells induce pulmonary fibrosis.

Mycobacteriosis outbreak caused by Mycobacterium aviumsubsp.avium detected through meat inspection in five porcine fattening farms (2013)
Journal Article
Pérez de Val, B., Grau-Roma, L., Segalés, J., Domingo, M., & Vidal, E. (2013). Mycobacteriosis outbreak caused by Mycobacterium aviumsubsp.avium detected through meat inspection in five porcine fattening farms. Veterinary Record, 174(4), Article 96. https://doi.org/10.1136/vr.101886

Between December 2010 and January 2011 a number (n=20) of cases were submitted to the Slaughterhouse Support Service (Servei de Suport a Escorxadors, SESC-CReSA), consisting of grossly nodular granulomatous and caseous lesions in pig carcasses from f... Read More about Mycobacteriosis outbreak caused by Mycobacterium aviumsubsp.avium detected through meat inspection in five porcine fattening farms.

Potential of a sequence-based antigenic distance measure to indicate equine influenza vaccine strain efficacy (2013)
Journal Article
Daly, J. M., & Elton, D. (2013). Potential of a sequence-based antigenic distance measure to indicate equine influenza vaccine strain efficacy. Vaccine, 31(51), https://doi.org/10.1016/j.vaccine.2013.06.070

The calculation of pepitope values, a sequence-based measure of antigenic distance between strains, was developed for human influenza. The potential to apply the pepitope value to equine influenza vaccine strain selection was assessed. There was a ne... Read More about Potential of a sequence-based antigenic distance measure to indicate equine influenza vaccine strain efficacy.

The impact of cafeteria diet feeding on physiology and anxiety-related behaviour in male and female Sprague-Dawley rats of different ages (2013)
Journal Article
Warneke, W., Klaus, S., Fink, H., Langley-Evans, S. C., & Voigt, J.-P. (2014). The impact of cafeteria diet feeding on physiology and anxiety-related behaviour in male and female Sprague-Dawley rats of different ages. Pharmacology Biochemistry and Behavior, 116, https://doi.org/10.1016/j.pbb.2013.11.016

There is emerging experimental evidence that hyper-energetic diets not only cause obesity but also impact on behaviour in rodents. A hyper-energetic comfort diet/cafeteria diet (CD) fed during early development programmes anxiety-related behaviour in... Read More about The impact of cafeteria diet feeding on physiology and anxiety-related behaviour in male and female Sprague-Dawley rats of different ages.

Use of contrast-enhanced ultrasonography in chronic pathologic canine testes (2013)
Journal Article
Volta, A., Manfredi, S., Vignoli, M., Russo, M., England, G., Rossi, F., …Gnudi, G. (2014). Use of contrast-enhanced ultrasonography in chronic pathologic canine testes. Reproduction in Domestic Animals, 49(2), https://doi.org/10.1111/rda.12250

Contrast-enhanced ultrasound with sulphur hexafluoride microbubbles was performed in seven healthy dogs without a history of reproductive pathology and with histologically confirmed normal testes and in 42 dogs with chronic scrotal anomalies. All dog... Read More about Use of contrast-enhanced ultrasonography in chronic pathologic canine testes.

The genetics of virus particle shape in equine influenza A virus (2013)
Journal Article
Elton, D., Bruce, E. A., Bryant, N., Wise, H. M., MacRae, S., Rash, A., …Digard, P. (2013). The genetics of virus particle shape in equine influenza A virus. Influenza and Other Respiratory Viruses, 7(s4), https://doi.org/10.1111/irv.12197

Background Many human strains of influenza A virus produce highly pleomorphic virus particles that at the extremes can be approximated as either spheres of around 100 nm diameter or filaments of similar cross-section but elongated to lengths of many... Read More about The genetics of virus particle shape in equine influenza A virus.

Behavioural changes in dairy cows with lameness in an automatic milking system (2013)
Journal Article
Miguel-Pacheco, G., Kaler, J., Remnant, J., Cheyne, L., Abbott, C., French, A. P., …Huxley, J. N. (2014). Behavioural changes in dairy cows with lameness in an automatic milking system. Applied Animal Behaviour Science, 150, 1-8. https://doi.org/10.1016/j.applanim.2013.11.003

There is a tendency worldwide for the automation of farms; this has included the introduction of automatic milking systems (AMS) in the dairy industry. Lameness in dairy cows is highly prevalent and painful. These impacts potentially affect not only... Read More about Behavioural changes in dairy cows with lameness in an automatic milking system.

A signature motif mediating selective interactions of BCL11A with the NR2E/F subfamily of orphan nuclear receptors (2013)
Journal Article
Chan, C. M., Fulton, J., Montiel-Duarte, C., Collins, H. M., Bharti, N., Wadelin, F. R., …Heery, D. M. (2013). A signature motif mediating selective interactions of BCL11A with the NR2E/F subfamily of orphan nuclear receptors. Nucleic Acids Research, 41(21), https://doi.org/10.1093/nar/gkt761

Despite their physiological importance, selective interactions between nuclear receptors (NRs) and their cofactors are poorly understood. Here, we describe a novel signature motif (F/YSXXLXXL/Y) in the developmental regulator BCL11A that facilitates... Read More about A signature motif mediating selective interactions of BCL11A with the NR2E/F subfamily of orphan nuclear receptors.