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Na+, K+-ATPase subunit composition in a human chondrocyte cell line; evidence for the presence of α1, α3, β1, β2 and β3 isoforms (2012)
Journal Article
Mobasheri, A., Trujillo, E., Arteaga, M., & Martin-Vasallo, P. (2012). Na+, K+-ATPase subunit composition in a human chondrocyte cell line; evidence for the presence of α1, α3, β1, β2 and β3 isoforms. International Journal of Molecular Sciences, 13(4), https://doi.org/10.3390/ijms13045019

Membrane transport systems participate in fundamental activities such as cell cycle control, proliferation, survival, volume regulation, pH maintenance and regulation of extracellular matrix synthesis. Multiple isoforms of Na+, K+-ATPase are expresse... Read More about Na+, K+-ATPase subunit composition in a human chondrocyte cell line; evidence for the presence of α1, α3, β1, β2 and β3 isoforms.

Expression of transient receptor potential vanilloid (TRPV) channels in different passages of articular chondrocytes (2012)
Journal Article
Hdud, I. M., El-Shafei, A. A., Loughna, P., Barrett-Jolley, R., & Mobasheri, A. (2012). Expression of transient receptor potential vanilloid (TRPV) channels in different passages of articular chondrocytes. International Journal of Molecular Sciences, 13(4), https://doi.org/10.3390/ijms13044433

Ion channels play important roles in chondrocyte mechanotransduction. The transient receptor potential vanilloid (TRPV) subfamily of ion channels consists of six members. TRPV1-4 are temperature sensitive calcium-permeable, relatively non-selective c... Read More about Expression of transient receptor potential vanilloid (TRPV) channels in different passages of articular chondrocytes.

Scientific evidence and rationale for the development of curcumin and resveratrol as nutraceutricals for joint health (2012)
Journal Article
Mobasheri, A., Henrotin, Y., Biesalski, H.-K., & Shakibaei, M. (2012). Scientific evidence and rationale for the development of curcumin and resveratrol as nutraceutricals for joint health. International Journal of Molecular Sciences, 13(4), https://doi.org/10.3390/ijms13044202

Interleukin 1β (IL-1β) and tumor necrosis factor α (TNF-α) are key cytokines that drive the production of inflammatory mediators and matrix-degrading enzymes in osteoarthritis (OA). These proinflammatory cytokines bind to their respective cell surfac... Read More about Scientific evidence and rationale for the development of curcumin and resveratrol as nutraceutricals for joint health.

Botanical Extracts from Rosehip (Rosa canina), Willow Bark (Salix alba), and Nettle Leaf (Urtica dioica) Suppress IL-1β-Induced NF-κB Activation in Canine Articular Chondrocytes (2012)
Journal Article
Shakibaei, M., Allaway, D., Nebrich, S., & Mobasheri, A. (2012). Botanical Extracts from Rosehip (Rosa canina), Willow Bark (Salix alba), and Nettle Leaf (Urtica dioica) Suppress IL-1β-Induced NF-κB Activation in Canine Articular Chondrocytes. Evidence-Based Complementary and Alternative Medicine, 2012, Article 509383. https://doi.org/10.1155/2012/509383

The aim of this study was to characterize the anti-inflammatory mode of action of botanical extracts from rosehip (Rosa canina), willow bark (Salix alba), and nettle leaf (Urtica dioica) in an in vitro model of primary canine articular chondrocytes.... Read More about Botanical Extracts from Rosehip (Rosa canina), Willow Bark (Salix alba), and Nettle Leaf (Urtica dioica) Suppress IL-1β-Induced NF-κB Activation in Canine Articular Chondrocytes.

A semi-parametric model for lactation curves: development and application (2012)
Journal Article
Madouasse, A., Browne, W., Huxley, J., Toni, F., & Green, M. (2012). A semi-parametric model for lactation curves: development and application. Preventive Veterinary Medicine, 105(1-2), https://doi.org/10.1016/j.prevetmed.2012.02.009

We propose a semi-parametric model for lactation curves that, along with stage of lactation, accounts for day of the year at milk recording and stage of gestation. Lactation is described as having 3 different phases defined by 2 change points of whic... Read More about A semi-parametric model for lactation curves: development and application.

Associations between udder health and reproductive performance in United Kingdom dairy cows (2012)
Journal Article
Hudson, C., Bradley, A. J., Breen, J., & Green, M. J. (2012). Associations between udder health and reproductive performance in United Kingdom dairy cows. Journal of Dairy Science, 95(7), https://doi.org/10.3168/jds.2011-4629

The objective of this research was to evaluate the relationship between udder health and reproductive performance in UK dairy cows. Data from 80 herds were restructured such that each unit of data represented a 2-d period during lactation where a cow... Read More about Associations between udder health and reproductive performance in United Kingdom dairy cows.

The LIMD1 protein bridges an association between the prolyl hydroxylases and VHL to repress HIF-1 activity (2012)
Journal Article
Foxler, D. E., Bridge, K. S., James, V., Webb, T. M., Mee, M., Wong, S. C. K., …Sharp, T. V. (2012). The LIMD1 protein bridges an association between the prolyl hydroxylases and VHL to repress HIF-1 activity. Nature Cell Biology, 14(2), 201-208. https://doi.org/10.1038/ncb2424

There are three prolyl hydroxylases (PHD1, 2 and 3) that regulate the hypoxia-inducible factors (HIFs), the master transcriptional regulators that respond to changes in intracellular O2 tension1,2. In high O2 tension (normoxia) the PHDs hydroxylate t... Read More about The LIMD1 protein bridges an association between the prolyl hydroxylases and VHL to repress HIF-1 activity.

Characterisation of retroviruses in the horse genome and their transcriptional activity via transcriptome sequencing (2012)
Journal Article
Brown, K., Moreton, J., Malla, S., Aboobaker, A. A., Emes, R. D., & Tarlinton, R. E. (2012). Characterisation of retroviruses in the horse genome and their transcriptional activity via transcriptome sequencing. Virology, 433(1), https://doi.org/10.1016/j.virol.2012.07.010

The recently released draft horse genome is incompletely characterised in terms of its repetitive
element profile. This paper presents characterisation of the endogenous retrovirus (ERVs) of the horse
genome based on a data-mining strategy using mur... Read More about Characterisation of retroviruses in the horse genome and their transcriptional activity via transcriptome sequencing.

Role of the rumen in copper and thiomolybdate absorption (2011)
Journal Article
Gould, L., & Kendall, N. R. (2011). Role of the rumen in copper and thiomolybdate absorption. Nutrition Research Reviews, 24(2), https://doi.org/10.1017/S0954422411000059

The rumen is the site of significant interactions between Cu, S and Mo. It also shows reactions between Cu, S and Fe. The interaction between Mo and S results in the formation of thiomolybdates, which in the absence of adequate quantities of rumen Cu... Read More about Role of the rumen in copper and thiomolybdate absorption.