Katherine Brown
Characterisation of retroviruses in the horse genome and their transcriptional activity via transcriptome sequencing
Brown, Katherine; Moreton, Joanna; Malla, Sunir; Aboobaker, A. Aziz; Emes, Richard D.; Tarlinton, Rachael E.
Authors
Joanna Moreton
Sunir Malla
A. Aziz Aboobaker
Richard D. Emes
Rachael E. Tarlinton
Abstract
The recently released draft horse genome is incompletely characterised in terms of its repetitive
element pro?le. This paper presents characterisation of the endogenous retrovirus (ERVs) of the horse
genome based on a data-mining strategy using murine leukaemia virus proteins as queries. 978 ERV
gene sequences were identi?ed. Sequences were identi?ed from the gamma, epsilon and betaretrovirus
genera. At least one full length gammaretroviral locus was identi?ed, though the gammaretroviral
sequences are very degenerate. Using these data the RNA expression of these ERVs were derived from
RNA transcriptome data from a variety of equine tissues. Unlike the well studied human and murine
ERVs there do not appear to be particular phylogenetic groups of equine ERVs that are more
transcriptionally active. Using this novel approach provided a more technically feasible method to
characterise ERV expression than previous studies.
Citation
Brown, K., Moreton, J., Malla, S., Aboobaker, A. A., Emes, R. D., & Tarlinton, R. E. (2012). Characterisation of retroviruses in the horse genome and their transcriptional activity via transcriptome sequencing. Virology, 433(1), https://doi.org/10.1016/j.virol.2012.07.010
Journal Article Type | Article |
---|---|
Publication Date | Jan 1, 2012 |
Deposit Date | Jul 21, 2015 |
Publicly Available Date | Jul 21, 2015 |
Journal | Virology |
Print ISSN | 0042-6822 |
Electronic ISSN | 0042-6822 |
Publisher | Elsevier |
Peer Reviewed | Peer Reviewed |
Volume | 433 |
Issue | 1 |
DOI | https://doi.org/10.1016/j.virol.2012.07.010 |
Public URL | https://nottingham-repository.worktribe.com/output/1008347 |
Publisher URL | http://www.sciencedirect.com/science/article/pii/S0042682212003595 |
Files
figure_1.tif
(16.2 Mb)
Other
Copyright Statement
Copyright information regarding this work can be found at the following address: http://creativecommons.org/licenses/by-nc-nd/4.0
figure_2.tif
(77 Mb)
Other
Copyright Statement
Copyright information regarding this work can be found at the following address: http://creativecommons.org/licenses/by-nc-nd/4.0
figure_3.tif
(128.3 Mb)
Other
Copyright Statement
Copyright information regarding this work can be found at the following address: http://creativecommons.org/licenses/by-nc-nd/4.0
figure_4.tif
(53.6 Mb)
Other
Copyright Statement
Copyright information regarding this work can be found at the following address: http://creativecommons.org/licenses/by-nc-nd/4.0
figure_5.tif
(37.4 Mb)
Other
Copyright Statement
Copyright information regarding this work can be found at the following address: http://creativecommons.org/licenses/by-nc-nd/4.0
figure_6.tif
(72.1 Mb)
Other
Copyright Statement
Copyright information regarding this work can be found at the following address: http://creativecommons.org/licenses/by-nc-nd/4.0
Copy of supplementary_table_1.pdf
(735 Kb)
PDF
Copyright Statement
Copyright information regarding this work can be found at the following address: http://creativecommons.org/licenses/by-nc-nd/4.0
Copy of supplementary_table_2.pdf
(30 Kb)
PDF
Copyright Statement
Copyright information regarding this work can be found at the following address: http://creativecommons.org/licenses/by-nc-nd/4.0
final draft.pdf
(153 Kb)
PDF
Copyright Statement
Copyright information regarding this work can be found at the following address: http://creativecommons.org/licenses/by-nc-nd/4.0
figure_legends.pdf
(7 Kb)
PDF
Copyright Statement
Copyright information regarding this work can be found at the following address: http://creativecommons.org/licenses/by-nc-nd/4.0
table_1.pdf
(71 Kb)
PDF
Copyright Statement
Copyright information regarding this work can be found at the following address: http://creativecommons.org/licenses/by-nc-nd/4.0
You might also like
Genome Reference Assembly for Bottlenecked Southern Australian Koalas
(2022)
Journal Article
Failure to detect Schmallenberg Virus in ram semen in the UK (2016-2018)
(2022)
Journal Article
Serum Cytokine Alterations Associated with Age of Patients with Nephropathia Epidemica
(2022)
Journal Article
Downloadable Citations
About Repository@Nottingham
Administrator e-mail: digital-library-support@nottingham.ac.uk
This application uses the following open-source libraries:
SheetJS Community Edition
Apache License Version 2.0 (http://www.apache.org/licenses/)
PDF.js
Apache License Version 2.0 (http://www.apache.org/licenses/)
Font Awesome
SIL OFL 1.1 (http://scripts.sil.org/OFL)
MIT License (http://opensource.org/licenses/mit-license.html)
CC BY 3.0 ( http://creativecommons.org/licenses/by/3.0/)
Powered by Worktribe © 2024
Advanced Search