Outputs (7)

Unveiling the gut bacteriome diversity and distribution in the national fish hilsa (Tenualosa ilisha) of Bangladesh (2024)
Journal Article
Kawser, A. Q. M. R., Hoque, M. N., Rahman, M. S., Sakif, T. I., Coffey, T. J., & Islam, T. (2024). Unveiling the gut bacteriome diversity and distribution in the national fish hilsa (Tenualosa ilisha) of Bangladesh. PLoS ONE, 19(5), Article e0303047. https://doi.org/10.1371/journal.pone.0303047

The field of fish microbiome research has rapidly been advancing, primarily focusing on farmed or laboratory fish species rather than natural or marine fish populations. This study sought to reveal the distinctive gut bacteriome composition and diver... Read More about Unveiling the gut bacteriome diversity and distribution in the national fish hilsa (Tenualosa ilisha) of Bangladesh.

A core genome multi-locus sequence typing scheme for Streptococcus uberis: an evolution in typing a genetically diverse pathogen (2024)
Journal Article
Whiley, D., Jolley, K., Blanchard, A., Coffey, T., & Leigh, J. (2024). A core genome multi-locus sequence typing scheme for Streptococcus uberis: an evolution in typing a genetically diverse pathogen. Microbial Genomics, 10(3), https://doi.org/10.1099/mgen.0.001225

Streptococcus uberis is a globally endemic and poorly controlled cause of bovine mastitis impacting the sustainability of the modern dairy industry. A core genome was derived from 579 newly sequenced S. uberis isolates, along with 305 publicly availa... Read More about A core genome multi-locus sequence typing scheme for Streptococcus uberis: an evolution in typing a genetically diverse pathogen.

Genomic heterogeneity of Dichelobacter nodosus within and between UK sheep flocks and between age groups within a flock (2020)
Journal Article
Davies, P. L., Blanchard, A. M., Staley, C. E., Bollard, N. J., Coffey, T. J., & Tötemeyer, S. (2020). Genomic heterogeneity of Dichelobacter nodosus within and between UK sheep flocks and between age groups within a flock. BMC Microbiology, 20, Article 107. https://doi.org/10.1186/s12866-020-01769-9

Background Footrot and interdigital dermatitis are endemic infectious diseases in all sheep farming regions, impairing welfare and production. The development of efficacious vaccines against the primary causative pathogen has been hampered by the ex... Read More about Genomic heterogeneity of Dichelobacter nodosus within and between UK sheep flocks and between age groups within a flock.

The applied development of a tiered multilocus sequence typing (MLST) scheme for Dichelobacter nodosus (2018)
Journal Article
Blanchard, A. M., Jolley, K. A., Maiden, M. C., Coffey, T. J., Maboni, G., Staley, C. E., …Tötemeyer, S. (in press). The applied development of a tiered multilocus sequence typing (MLST) scheme for Dichelobacter nodosus. Frontiers in Microbiology, 9, Article 551. https://doi.org/10.3389/fmicb.2018.00551

Dichelobacter nodosus (D. nodosus) is the causative pathogen of ovine footrot, a disease that has a significant welfare and financial impact on the global sheep industry. Previous studies into the phylogenetics of D. nodosus have focused on Australia... Read More about The applied development of a tiered multilocus sequence typing (MLST) scheme for Dichelobacter nodosus.

A rapid IL-17 response to Cryptosporidium parvum in the bovine intestine (2017)
Journal Article
Drinkall, E., Wass, M. J., Coffey, T. J., & Flynn, R. J. (in press). A rapid IL-17 response to Cryptosporidium parvum in the bovine intestine. Veterinary Immunology and Immunopathology, 191, https://doi.org/10.1016/j.vetimm.2017.07.009

Cryptosporidium parvum causes diarrhoea, due to villi damage, in livestock and humans globally. Immunity develops after repeated infections but initial infections can be severe, highlighting the importance of early infection dynamics. We have modelle... Read More about A rapid IL-17 response to Cryptosporidium parvum in the bovine intestine.

Subset-specific expression of toll-like receptors by bovine afferent lymph dendritic cells (2017)
Journal Article
Werling, D., Hope, J. C., Siddiqui, N., Widdison, S., Russell, C., Sopp, P., & Coffey, T. J. (2017). Subset-specific expression of toll-like receptors by bovine afferent lymph dendritic cells. Frontiers in Veterinary Science, 4, Article 44. https://doi.org/10.3389/fvets.2017.00044

Within the ruminant system, several possibilities exist to generate dendritic cells migrating out from the tissue into the regional draining lymph nodes as afferent lymph dendritic cells (ALDCs). Here, we analyzed toll-like receptor (TLR) 1–10 mRNA e... Read More about Subset-specific expression of toll-like receptors by bovine afferent lymph dendritic cells.

Virulence related sequences; insights provided by comparative genomics of Streptococcus uberis of differing virulence (2015)
Journal Article

Background Streptococcus uberis, a Gram-positive, catalase-negative member of the family Streptococcaceae is an important environmental pathogen responsible for a significant proportion of subclinical and clinical bovine intramammary infections. C... Read More about Virulence related sequences; insights provided by comparative genomics of Streptococcus uberis of differing virulence.