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A Pictorial Essay of Coronary Artery Anomalies on Coronary CT Angiography: A Single-Centre Observational Study. (2024)
Journal Article
Ahmad, A., Roplekar, S., & Podlasek, A. (in press). A Pictorial Essay of Coronary Artery Anomalies on Coronary CT Angiography: A Single-Centre Observational Study. Cureus, 16(7), Article e64398. https://doi.org/10.7759/cureus.64398

Background

Congenital anomalies of the coronary artery anatomy (CAAs) encompass a spectrum of disorders, often asymptomatic but potentially carrying severe clinical implications such as arrhythmia, chest pain, myocardial infarction, or sudden dea... Read More about A Pictorial Essay of Coronary Artery Anomalies on Coronary CT Angiography: A Single-Centre Observational Study..

Recent Advances in Locoregional Therapy of Hepatocellular Carcinoma (2023)
Journal Article
Podlasek, A., Abdulla, M., Broering, D., & Bzeizi, K. (2023). Recent Advances in Locoregional Therapy of Hepatocellular Carcinoma. Cancers, 15(13), Article 3347. https://doi.org/10.3390/cancers15133347

Hepatocellular carcinoma (HCC) is responsible for 90% of primary hepatic cancer cases, and its incidence with associated morbidity and mortality is growing worldwide. In recent decades, there has been a revolution in HCC treatment. There are three ma... Read More about Recent Advances in Locoregional Therapy of Hepatocellular Carcinoma.

World Federation for Interventional Stroke Treatment (WIST) multispecialty training guidelines for endovascular stroke intervention (2023)
Journal Article
Grunwald, I. Q., Mathias, K., Bertog, S., Snyder, K. V., Sievert, H., Siddiqui, A., …Hopkins, N. L. (2023). World Federation for Interventional Stroke Treatment (WIST) multispecialty training guidelines for endovascular stroke intervention. Cardiovascular Revascularization Medicine, 53, 67-72. https://doi.org/10.1016/j.carrev.2023.03.004

Introduction: Today, endovascular treatment (EVT) is the therapy of choice for strokes due to acute large vessel occlusion, irrespective of prior thrombolysis. This necessitates fast, coordinated multi-specialty collaboration. Currently, in most coun... Read More about World Federation for Interventional Stroke Treatment (WIST) multispecialty training guidelines for endovascular stroke intervention.

Thrombectomy-Capable Stroke Centre—A Key to Acute Stroke Care System Improvement? Retrospective Analysis of Safety and Efficacy of Endovascular Treatment in Cardiac Cathlab (2023)
Journal Article
Pawłowski, K., Dziadkiewicz, A., Podlasek, A., Klaudel, J., Mączkowiak, A., & Szołkiewicz, M. (2023). Thrombectomy-Capable Stroke Centre—A Key to Acute Stroke Care System Improvement? Retrospective Analysis of Safety and Efficacy of Endovascular Treatment in Cardiac Cathlab. International Journal of Environmental Research and Public Health, 20(3), Article 2232. https://doi.org/10.3390/ijerph20032232

The optimal structure of the acute ischaemic stroke treatment network is unknown and eagerly sought. To make it most effective, different treatment and transportation strategies have been developed and investigated worldwide. Since only a fraction of... Read More about Thrombectomy-Capable Stroke Centre—A Key to Acute Stroke Care System Improvement? Retrospective Analysis of Safety and Efficacy of Endovascular Treatment in Cardiac Cathlab.

Clinical and Procedural Outcomes with or without Balloon Guide Catheters during Endovascular Thrombectomy in Acute Ischemic Stroke: A Systematic Review and Meta-analysis with First-line Technique Subgroup Analysis (2021)
Journal Article
Podlasek, A., Dhillon, P. S., Jewett, G., Shahein, A., Goyal, M., & Almekhlafi, M. (2021). Clinical and Procedural Outcomes with or without Balloon Guide Catheters during Endovascular Thrombectomy in Acute Ischemic Stroke: A Systematic Review and Meta-analysis with First-line Technique Subgroup Analysis. American Journal of Neuroradiology, 42(8), 1464-1471. https://doi.org/10.3174/ajnr.a7164

BACKGROUND: Balloon guide catheters are increasingly used to improve clot retrieval by temporarily stopping proximal blood flow during endovascular thrombectomy. PURPOSE: Our aim was to provide a summary of the literature comparing the procedural and... Read More about Clinical and Procedural Outcomes with or without Balloon Guide Catheters during Endovascular Thrombectomy in Acute Ischemic Stroke: A Systematic Review and Meta-analysis with First-line Technique Subgroup Analysis.

Simultaneous measurement of gastric emptying of a soup test meal using MRI and gamma scintigraphy (2020)
Journal Article
Khalaf, A., Hoad, C. L., Blackshaw, E., Alyami, J., Spiller, R. C., Gowland, P. A., …Marciani, L. (2020). Simultaneous measurement of gastric emptying of a soup test meal using MRI and gamma scintigraphy. Diagnostics, 10(3), Article 170. https://doi.org/10.3390/diagnostics10030170

Measurement of gastric emptying is of clinical value for a range of conditions. Gamma scintigraphy (GS) has an established role, but the use of magnetic resonance imaging (MRI) has recently increased. Previous comparison studies between MRI and GS sh... Read More about Simultaneous measurement of gastric emptying of a soup test meal using MRI and gamma scintigraphy.

Nasal Administration and Plasma Pharmacokinetics of Parathyroid Hormone Peptide PTH 1-34 for the Treatment of Osteoporosis (2019)
Journal Article
Pearson, R. G., Masud, T., Blackshaw, E., Naylor, A., Hinchcliffe, M., Jeffery, K., …Perkins, A. C. (2019). Nasal Administration and Plasma Pharmacokinetics of Parathyroid Hormone Peptide PTH 1-34 for the Treatment of Osteoporosis. Pharmaceutics, 11(6), Article 265. https://doi.org/10.3390/pharmaceutics11060265

Nasal delivery of large peptides such as parathyroid 1-34 (PTH 1-34) can benefit from a permeation enhancer to promote absorption across the nasal mucosa into the bloodstream. Previously, we have published an encouraging bioavailability (78%), relati... Read More about Nasal Administration and Plasma Pharmacokinetics of Parathyroid Hormone Peptide PTH 1-34 for the Treatment of Osteoporosis.

MRS and DTI evidence of progressive posterior cingulate cortex and corpus callosum injury in the hyper-acute phase after Traumatic Brain Injury (2019)
Journal Article
Lawrence, T. P., Steel, A., Ezra, M., Speirs, M., Pretorius, P. M., Douaud, G., …Voets, N. L. (2019). MRS and DTI evidence of progressive posterior cingulate cortex and corpus callosum injury in the hyper-acute phase after Traumatic Brain Injury. Brain Injury, 33(7), 854-868. https://doi.org/10.1080/02699052.2019.1584332

The posterior cingulate cortex (PCC) and corpus callosum (CC) are susceptible to trauma, but injury often evades detection. PCC Metabolic disruption may predict CC white matter tract injury and the secondary cascade responsible for progression. While... Read More about MRS and DTI evidence of progressive posterior cingulate cortex and corpus callosum injury in the hyper-acute phase after Traumatic Brain Injury.

Hierarchical heterogeneity across human cortex shapes large-scale neural dynamics (2019)
Journal Article
Demirtas, M., Burt, J. B., Helmer, M., Ji, J. L., Adkinson, B. D., Glasser, M. F., …Murray, J. D. (2019). Hierarchical heterogeneity across human cortex shapes large-scale neural dynamics. Neuron, 101(6), 1181-1194.e13. https://doi.org/10.1016/j.neuron.2019.01.017

The large-scale organization of dynamical neural activity across cortex emerges through long-range interactions among local circuits. We hypothesized that large-scale dynamics are also shaped by heterogeneity of intrinsic local properties across cort... Read More about Hierarchical heterogeneity across human cortex shapes large-scale neural dynamics.