Outputs (559)

Helicobacter pylori eradication for primary prevention of peptic ulcer bleeding in older patients prescribed aspirin in primary care (HEAT): a randomised, double-blind, placebo-controlled trial (2022)
Journal Article
Hawkey, C., Avery, A., Coupland, C. A., Crooks, C., Dumbleton, J., Hobbs, F. D. R., …Hodgson, S. (2022). Helicobacter pylori eradication for primary prevention of peptic ulcer bleeding in older patients prescribed aspirin in primary care (HEAT): a randomised, double-blind, placebo-controlled trial. Lancet, 400(10363), 1597-1606. https://doi.org/10.1016/S0140-6736%2822%2901843-8

Background: Peptic ulcers in patients receiving aspirin are associated with Helicobacter pylori infection. We aimed to investigate whether H pylori eradication would protect against aspirin-associated ulcer bleeding. Methods: We conducted a randomise... Read More about Helicobacter pylori eradication for primary prevention of peptic ulcer bleeding in older patients prescribed aspirin in primary care (HEAT): a randomised, double-blind, placebo-controlled trial.

Design decisions and data completeness for experience sampling methods used in psychosis: systematic review (2022)
Journal Article
Deakin, E., Ng, F., Young, E., Thorpe, N., Newby, C., Coupland, C., Craven, M., & Slade, M. (2022). Design decisions and data completeness for experience sampling methods used in psychosis: systematic review. BMC Psychiatry, 22, Article 669. https://doi.org/10.1186/s12888-022-04319-x

Background: The experience sampling method (ESM) is an intensive longitudinal research method. Participants complete questionnaires at multiple times about their current or very recent state. The design of ESM studies is complex. People with psychosi... Read More about Design decisions and data completeness for experience sampling methods used in psychosis: systematic review.

European Physician Survey Characterizing the Clinical Pathway and Treatment Patterns of Patients Post-Myocardial Infarction (2022)
Journal Article
Qureshi, N., Antoniou, S., Cornel, J. H., Schiele, F., Perrone-Filardi, P., Brachmann, J., …González-Juanatey, J. R. (2022). European Physician Survey Characterizing the Clinical Pathway and Treatment Patterns of Patients Post-Myocardial Infarction. Advances in Therapy, https://doi.org/10.1007/s12325-022-02344-6

Introduction: The 2019 European Society of Cardiology and European Atherosclerosis Society (2019 ESC/EAS) guidelines stress the importance of managing low-density lipoprotein cholesterol (LDL-C) after myocardial infarction (MI) to reduce the risk of... Read More about European Physician Survey Characterizing the Clinical Pathway and Treatment Patterns of Patients Post-Myocardial Infarction.

Humoral and cellular immunity in patients with rare autoimmune rheumatic diseases following SARS-CoV-2 vaccination (2022)
Journal Article
Gumber, L., Gomez, N., Hopkins, G., Tucis, D., Bartlett, L., Ayling, K., …Fairclough, L. (2023). Humoral and cellular immunity in patients with rare autoimmune rheumatic diseases following SARS-CoV-2 vaccination. Rheumatology, 62(6), 2294-2303. https://doi.org/10.1093/rheumatology/keac574

Objectives: COVID-19 vaccine responses in rare autoimmune rheumatic diseases (RAIRD) remain poorly understood, in particular there is little known about whether people develop effective T-cell responses. We conducted a prospective cohort study to eva... Read More about Humoral and cellular immunity in patients with rare autoimmune rheumatic diseases following SARS-CoV-2 vaccination.

Electronic health record-based facilitation of familial hypercholesterolaemia detection sensitivity of different algorithms in genetically confirmed patients (2022)
Journal Article
Mohammadnia, N., Akyea, R. K., Qureshi, N., Bax, W. A., & Cornel, J. H. (2022). Electronic health record-based facilitation of familial hypercholesterolaemia detection sensitivity of different algorithms in genetically confirmed patients. European Heart Journal – Digital Health, 3(4), 578-586. https://doi.org/10.1093/ehjdh/ztac059

Aims: Familial hypercholesterolaemia (FH) is a disorder of LDL cholesterol clearance, resulting in increased risk of cardiovascular disease. Recently, we developed a Dutch Lipid Clinic Network (DLCN) criteria-based algorithm to facilitate FH detectio... Read More about Electronic health record-based facilitation of familial hypercholesterolaemia detection sensitivity of different algorithms in genetically confirmed patients.

Promoting and maintaining changes in smoking behaviour for patients following discharge from a smokefree mental health inpatient stay: Development of a complex intervention using the Behaviour Change Wheel. (2022)
Journal Article
Shoesmith, E., Huddlestone, L., Pervin, J., Shahab, L., Coventry, P., Coleman, T., …Ratschen, E. (2023). Promoting and maintaining changes in smoking behaviour for patients following discharge from a smokefree mental health inpatient stay: Development of a complex intervention using the Behaviour Change Wheel. Nicotine & Tobacco Research, 25(4), 729-737. https://doi.org/10.1093/ntr/ntac242

Evidence suggests that smokers can successfully quit, remain abstinent or reduce smoking during a smokefree mental health inpatient stay, provided behavioural/pharmacological support are offered. However, few evidence-based strategies to prevent the... Read More about Promoting and maintaining changes in smoking behaviour for patients following discharge from a smokefree mental health inpatient stay: Development of a complex intervention using the Behaviour Change Wheel..

Allopurinol versus usual care in UK patients with ischaemic heart disease (ALL-HEART): a multicentre, prospective, randomised, open-label, blinded-endpoint trial (2022)
Journal Article
Mackenzie, I. S., Hawkey, C. J., Ford, I., Greenlaw, N., Pigazzani, F., Rogers, A., …MacDonald, T. M. (2022). Allopurinol versus usual care in UK patients with ischaemic heart disease (ALL-HEART): a multicentre, prospective, randomised, open-label, blinded-endpoint trial. Lancet, 400(10359), 1195-1205. https://doi.org/10.1016/S0140-6736%2822%2901657-9

Background: Allopurinol is a urate-lowering therapy used to treat patients with gout. Previous studies have shown that allopurinol has positive effects on several cardiovascular parameters. The ALL-HEART study aimed to determine whether allopurinol t... Read More about Allopurinol versus usual care in UK patients with ischaemic heart disease (ALL-HEART): a multicentre, prospective, randomised, open-label, blinded-endpoint trial.

Risk Factors and Changes in Depression and Anxiety over Time in New Zealand during COVID-19: A Longitudinal Cohort Study (2022)
Journal Article
Law, M., Gasteiger, N., Vedhara, K., Massey, A., Jia, R., Ayling, K., …Broadbent, E. (2022). Risk Factors and Changes in Depression and Anxiety over Time in New Zealand during COVID-19: A Longitudinal Cohort Study. Psych, 4(4), 706-716. https://doi.org/10.3390/psych4040052

This longitudinal study investigated changes in and risk factors for anxiety and depression during the COVID-19 pandemic in a New Zealand cohort. Online surveys were distributed to 681 participants at three time-points: May 2020 (Time 1), August–Sept... Read More about Risk Factors and Changes in Depression and Anxiety over Time in New Zealand during COVID-19: A Longitudinal Cohort Study.

Understanding factors that could influence patient acceptability of the use of the PINCER intervention in primary care: A qualitative exploration using the Theoretical Framework of Acceptability (2022)
Journal Article
Laing, L., Salema, N.-E., Jeffries, M., Shamsuddin, A., Sheikh, A., Chuter, A., …Keers, R. N. (2022). Understanding factors that could influence patient acceptability of the use of the PINCER intervention in primary care: A qualitative exploration using the Theoretical Framework of Acceptability. PLoS ONE, 17(10), Article e0275633. https://doi.org/10.1371/journal.pone.0275633

Introduction Medication errors are an important cause of morbidity and mortality. The pharmacist-led IT-based intervention to reduce clinically important medication errors (PINCER) intervention was shown to reduce medication errors when tested in a c... Read More about Understanding factors that could influence patient acceptability of the use of the PINCER intervention in primary care: A qualitative exploration using the Theoretical Framework of Acceptability.

Electronic prescribing systems in hospitals to improve medication safety: a multimethods research programme (2022)
Journal Article
Sheikh, A., Coleman, J., Chuter, A., Williams, R., Lilford, R., Slee, A., …Watson, N. (2022). Electronic prescribing systems in hospitals to improve medication safety: a multimethods research programme. Programme Grants for Applied Research, 10(7), 1-164. https://doi.org/10.3310/KSRS2009

Background: There is a need to identify approaches to reduce medication errors. Interest has converged on ePrescribing systems that incorporate computerised provider order entry and clinical decision support functionality. Objectives: We sought to de... Read More about Electronic prescribing systems in hospitals to improve medication safety: a multimethods research programme.