Outputs (559)

Cost-Effectiveness of Screening Algorithms for Familial Hypercholesterolaemia in Primary Care (2022)
Journal Article
Jones, M., Akyea, R. K., Payne, K., Humphries, S. E., Abdul-Hamid, H., Weng, S., & Qureshi, N. (2022). Cost-Effectiveness of Screening Algorithms for Familial Hypercholesterolaemia in Primary Care. Journal of Personalized Medicine, 12(3), Article 330. https://doi.org/10.3390/jpm12030330

Although familial hypercholesterolemia (FH) screening within primary care is considered cost-effective, which screening approach is cost-effective has not been established. This study determines the cost-effectiveness of six case-finding strategies f... Read More about Cost-Effectiveness of Screening Algorithms for Familial Hypercholesterolaemia in Primary Care.

Association between smoking, e-cigarette use and severe COVID-19: A cohort study (2022)
Journal Article
Gao, M., Aveyard, P., Lindson, N., Hartmann-Boyce, J., Watkinson, P., Young, D., Coupland, C., Clift, A. K., Harrison, D., Gould, D., Pavord, I. D., Smith, M., & Hippisley-Cox, J. (2022). Association between smoking, e-cigarette use and severe COVID-19: A cohort study. International Journal of Epidemiology, 51(4), 1062-1072. https://doi.org/10.1093/ije/dyac028

Background: Smoking is a risk factor for most respiratory infections, but it may protect against SARS-CoV-2 infection. The objective was to assess whether smoking and e-cigarette use were associated with severe COVID-19. Methods: This cohort ran from... Read More about Association between smoking, e-cigarette use and severe COVID-19: A cohort study.

The Childhood Cancer Diagnosis (CCD) Study: a UK observational study to describe referral pathways and quantify diagnostic intervals in children and young people with cancer (2022)
Journal Article
Shanmugavadivel, D., Liu, J.-F., Ball-Gamble, A., Polanco, A., Vedhara, K., Walker, D., & Ojha, S. (2022). The Childhood Cancer Diagnosis (CCD) Study: a UK observational study to describe referral pathways and quantify diagnostic intervals in children and young people with cancer. BMJ Open, 12(2), Article e058744. https://doi.org/10.1136/bmjopen-2021-058744

Introduction: Childhood cancer is diagnosed in 400 000 children and young people (CYP) aged 0–19 years worldwide annually. In the UK, a child’s cumulative cancer risk increases from 1 in 4690 from birth to aged 1, to 1 in 470 by age 15. Once diagnose... Read More about The Childhood Cancer Diagnosis (CCD) Study: a UK observational study to describe referral pathways and quantify diagnostic intervals in children and young people with cancer.

Childhood Cancer Diagnosis (CCD) Study: a UK observational study to describe referral pathways and quantify diagnostic intervals in children and young people with cancer (2022)
Journal Article
Shanmugavadivel, D., Liu, J.-F., Gamble, A., Polanco, A., Vedhara, K., Walker, D., & Ojha, S. (2022). Childhood Cancer Diagnosis (CCD) Study: a UK observational study to describe referral pathways and quantify diagnostic intervals in children and young people with cancer. BMJ Open, 12(2), Article e058744. https://doi.org/10.1136/bmjopen-2021-058744

Introduction: Childhood cancer is diagnosed in 400,000 children and young people (CYP) aged 0-19 years worldwide annually. In the UK, a child’s cumulative cancer risk increases from 1 in 4690 from birth to aged 1, to 1 in 470 by age 15. Once diagnose... Read More about Childhood Cancer Diagnosis (CCD) Study: a UK observational study to describe referral pathways and quantify diagnostic intervals in children and young people with cancer.

Development of models of care coordination for rare conditions: A qualitative study (2022)
Journal Article
Walton, H., Simpson, A., Ramsay, A. I., Hunter, A., Jones, J., Ng, P. L., Leeson-Beevers, K., Bloom, L., Kai, J., Kokocinska, M., Sutcliffe, A. G., Morris, S., & Fulop, N. J. (2022). Development of models of care coordination for rare conditions: A qualitative study. Orphanet Journal of Rare Diseases, 17, Article 49. https://doi.org/10.1101/2021.11.16.21266395

Introduction: Improving care coordination for people with rare conditions may help to reduce burden on patients and carers and improve the care that patients receive. We recently developed a taxonomy of different ways of coordinating care for rare co... Read More about Development of models of care coordination for rare conditions: A qualitative study.

Recruitment to a large scale randomised controlled clinical trial in primary care: the Helicobacter Eradication Aspirin Trial (HEAT) (2022)
Journal Article
Stevenson, D. J., Avery, A. J., Coupland, C., Hobbs, F. D. R., Kendrick, D., Moore, M. V., Morris, C., Rubin, G. P., Smith, M. D., Hawkey, C. J., & Dumbleton, J. S. (2022). Recruitment to a large scale randomised controlled clinical trial in primary care: the Helicobacter Eradication Aspirin Trial (HEAT). Trials, 23(1), Article 140. https://doi.org/10.1186/s13063-022-06054-w

Background: The Helicobacter Eradication Aspirin Trial (HEAT) is a multicentre, double blind, randomised controlled trial investigating whether Helicobacter (H.) pylori eradication reduces hospitalisation for peptic ulcer bleeding. Recruited particip... Read More about Recruitment to a large scale randomised controlled clinical trial in primary care: the Helicobacter Eradication Aspirin Trial (HEAT).

‘It is designed for everybody to find their own level and to improve themselves’; views of older people and instructors of the Falls Management Exercise (FaME) programme (2022)
Journal Article
Gumber, L., Timmons, S., Coupland, C., Gladman, J., Lliffe, S., Kendrick, D., Lafond, N., Logan, P., Masud, T., Skelton, D., Timblin, C., & Orton, E. (2022). ‘It is designed for everybody to find their own level and to improve themselves’; views of older people and instructors of the Falls Management Exercise (FaME) programme. Age and Ageing, 51(2), Article afac023. https://doi.org/10.1093/ageing/afac023

Background: Older adults are at increased risk of falls due to ageing, decreased muscle strength and impaired balance. Clinical trials have demonstrated the efficacy and effectiveness of the Falls Management Exercise (FaME) programme in improving fun... Read More about ‘It is designed for everybody to find their own level and to improve themselves’; views of older people and instructors of the Falls Management Exercise (FaME) programme.

Using Forum Theatre to mobilise knowledge and improve NHS care: the Enhancing Post-injury Psychological Intervention and Care (EPPIC) study (2022)
Journal Article
Beckett, K., Deave, T., McBride, T., May, A. L., Gabbay, J., Kapoulas, U., Long, A., Warburton, G., Wogan, C., Cox, L., Thompson, J., Spencer, F., & Kendrick, D. (2022). Using Forum Theatre to mobilise knowledge and improve NHS care: the Enhancing Post-injury Psychological Intervention and Care (EPPIC) study. Evidence and Policy, 18(2), 236-264. https://doi.org/10.1332/174426421X16420902769508

Background: Evidence regarding the impact of psychological problems on recovery from injury has limited influence on practice. Mindlines show effective practice requires diverse knowledge which is generally socially transmitted. Aims and objectives:... Read More about Using Forum Theatre to mobilise knowledge and improve NHS care: the Enhancing Post-injury Psychological Intervention and Care (EPPIC) study.

Behaviours of Patients Who Take Their Strong Opioids as Unmeasured ‘Sips’ (2022)
Journal Article
Perkins, P., Parkinson, A., Hebdon, R., & Akyea, R. K. (2022). Behaviours of Patients Who Take Their Strong Opioids as Unmeasured ‘Sips’. Journal of Pain and Symptom Management, 63(6), e691-697. https://doi.org/10.1016/j.jpainsymman.2022.01.018

Context: Some patients take their strong opioid painkillers as unmeasured sips. Objectives: To investigate how and why patients take their medication in this way. Methods: Patient receiving specialist palliative care who take their strong opioid pain... Read More about Behaviours of Patients Who Take Their Strong Opioids as Unmeasured ‘Sips’.

The risk of all-cause and cause-specific mortality in people prescribed mirtazapine: an active comparator cohort study using electronic health records (2022)
Journal Article
Joseph, R. M., Jack, R. H., Morriss, R., Knaggs, R. D., Butler, D., Hollis, C., Hippisley-Cox, J., & Coupland, C. (2022). The risk of all-cause and cause-specific mortality in people prescribed mirtazapine: an active comparator cohort study using electronic health records. BMC Medicine, 20(1), Article 43. https://doi.org/10.1186/s12916-022-02247-x

Background
Studies have reported an increased risk of mortality among people prescribed mirtazapine compared to other antidepressants. The study aimed to compare all-cause and cause-specific mortality between adults prescribed mirtazapine or other s... Read More about The risk of all-cause and cause-specific mortality in people prescribed mirtazapine: an active comparator cohort study using electronic health records.