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Outputs (63)

Low protein diet and methyl-donor supplements modify testicular physiology in mice (2020)
Journal Article
Morgan, H. L., Ampong, I., Eid, N., Rouillon, C., Griffiths, H. R., & Watkins, A. J. (2020). Low protein diet and methyl-donor supplements modify testicular physiology in mice. Reproduction, 159(5), 627-641. https://doi.org/10.1530/rep-19-0435

The link between male diet and sperm quality has received significant investigation. However, the impact diet and dietary supplements have on the testicular environment has been examined to a lesser extent. Here, we establish the impact of a sub-opti... Read More about Low protein diet and methyl-donor supplements modify testicular physiology in mice.

Development and Reporting of Prediction Models: Guidance for Authors From Editors of Respiratory, Sleep, and Critical Care Journals (2020)
Journal Article
Leisman, D. E., Harhay, M. O., Lederer, D. J., Abramson, M., Adjei, A. A., Bakker, J., …Maslove, D. M. (2020). Development and Reporting of Prediction Models: Guidance for Authors From Editors of Respiratory, Sleep, and Critical Care Journals. Critical Care Medicine, 48(5), 623-633. https://doi.org/10.1097/ccm.0000000000004246

Prediction models aim to use available data to predict a health state or outcome that has not yet been observed. Prediction is primarily relevant to clinical practice, but is also used in research, and administration. While prediction modeling involv... Read More about Development and Reporting of Prediction Models: Guidance for Authors From Editors of Respiratory, Sleep, and Critical Care Journals.

Phenotypic and genetic spectrum of epilepsy with myoclonic atonic seizures (2020)
Journal Article
Tang, S., Addis, L., Smith, A., Topp, S. D., Pendziwiat, M., Mei, D., …Pal, D. K. (2020). Phenotypic and genetic spectrum of epilepsy with myoclonic atonic seizures. Epilepsia, 61(5), 995-1007. https://doi.org/10.1111/epi.16508

Objective: We aimed to describe the extent of neurodevelopmental impairments and
identify the genetic etiologies in a large cohort of patients with epilepsy with myoclonic
atonic seizures (MAE).
Methods: We deeply phenotyped MAE patients for epile... Read More about Phenotypic and genetic spectrum of epilepsy with myoclonic atonic seizures.

The haemodynamics of the human placenta in utero (2020)
Journal Article
Dellschaft, N. S., Hutchinson, G., Shah, S., Jones, N. W., Bradley, C., Leach, L., …Gowland, P. A. (2020). The haemodynamics of the human placenta in utero. PLoS Biology, 18(5), Article e3000676. https://doi.org/10.1371/journal.pbio.3000676

© 2020 Dellschaft et al. We have used magnetic resonance imaging (MRI) to provide important new insights into the function of the human placenta in utero. We have measured slow net flow and high net oxygenation in the placenta in vivo, which are cons... Read More about The haemodynamics of the human placenta in utero.

Thioredoxin system protein expression is associated with poor clinical outcome in adult and paediatric gliomas and medulloblastomas (2020)
Journal Article
Martin, S., Yao, A., Storr, S. J., Al-Hadyan, K., Rahman, R., Smith, S., …Paine, S. (2020). Thioredoxin system protein expression is associated with poor clinical outcome in adult and paediatric gliomas and medulloblastomas. Molecular Neurobiology, 57(7), 2889–2901. https://doi.org/10.1007/s12035-020-01928-z

The thioredoxin (Trx) system is an important enzyme family that regulates cellular redox homeostasis. Protein expression of Trx system family members has been assessed in various cancers and linked to various clinicopathological variables, disease pr... Read More about Thioredoxin system protein expression is associated with poor clinical outcome in adult and paediatric gliomas and medulloblastomas.

Regulatory mechanisms for natriuretic peptide signalling in sheep granulosa cells (2020)
Journal Article
Alhamdan, R., Maalouf, W. E., Campbell, B. K., Hernandez-Medrano, J., & Marsters, P. (2020). Regulatory mechanisms for natriuretic peptide signalling in sheep granulosa cells. Journal of Molecular Endocrinology, 64(4), 223-234. https://doi.org/10.1530/jme-20-0034

Natriuretic peptides (NPs) have been reported to have critical roles in follicular development and oocyte maturation in rodents. This study aimed to extend our current understanding of NP-mediated signalling pathways and mechanisms of action in the f... Read More about Regulatory mechanisms for natriuretic peptide signalling in sheep granulosa cells.

Accurate neonatal heart rate monitoring using a new wireless, cap mounted device (2020)
Journal Article
Henry, C., Shipley, L., Ward, C., Mirahmadi, S., Liu, C., Morgan, S., …Sharkey, D. (2020). Accurate neonatal heart rate monitoring using a new wireless, cap mounted device. Acta Paediatrica, 110(1), 72-78. https://doi.org/10.1111/apa.15303

© 2020 The Authors. Acta Paediatrica published by John Wiley & Sons Ltd on behalf of Foundation Acta Paediatrica Aim: A device for newborn heart rate (HR) monitoring at birth that is compatible with delayed cord clamping and minimises hypothermia r... Read More about Accurate neonatal heart rate monitoring using a new wireless, cap mounted device.

Bovine Sperm Sexing Alters Sperm Morphokinetics and Subsequent Early Embryonic Development (2020)
Journal Article
Steele, H., Makri, D., Maalouf, W. E., Reese, S., & Kölle, S. (2020). Bovine Sperm Sexing Alters Sperm Morphokinetics and Subsequent Early Embryonic Development. Scientific Reports, 10(1), Article 6255. https://doi.org/10.1038/s41598-020-63077-6

In artificial insemination the use of sex-sorted bovine sperm results in reduced conception, the causes of which are only partly understood. Therefore, we set out to investigate the effects of sexing on bovine sperm function and early embryonic devel... Read More about Bovine Sperm Sexing Alters Sperm Morphokinetics and Subsequent Early Embryonic Development.

Smoking ban in cars protects children, but is vaping 'The Elephant in the Car'? (2020)
Journal Article
Ng, C., & Smyth, A. R. (2020). Smoking ban in cars protects children, but is vaping 'The Elephant in the Car'?. Thorax, 75(4), 297. https://doi.org/10.1136/thoraxjnl-2020-214660

In March 2006, smoking in public places was banned in Scotland. The following year a similar ban was introduced in England — the last of the UK home nations to adopt this policy. At the time, some suggested that the ban might paradoxically increase c... Read More about Smoking ban in cars protects children, but is vaping 'The Elephant in the Car'?.