Outputs (9)

Infection prevention and control in cystic fibrosis: An update of a systematic review of interventions (2024)
Journal Article
Rowbotham, N. J., Smith, S., Jahnke, N., Milczanowski, S., Elliott, Z. C., Prayle, A. P., & Smyth, A. R. (2024). Infection prevention and control in cystic fibrosis: An update of a systematic review of interventions. Journal of Cystic Fibrosis, https://doi.org/10.1016/j.jcf.2024.08.004

Preventing transmissible infection is a priority in cystic fibrosis (CF) care. This is an update of a systematic review of the evidence for infection prevention and control interventions in CF.

Our full protocol can be found on PROSPERO (CRD420181... Read More about Infection prevention and control in cystic fibrosis: An update of a systematic review of interventions.

Industry influence in healthcare harms patients: myth or maxim? (2022)
Journal Article
Trayer, J., Rowbotham, N. J., Boyle, R. J., & Smyth, A. R. (2022). Industry influence in healthcare harms patients: myth or maxim?. Breathe, 18(2), Article 220010. https://doi.org/10.1183/20734735.0010-2022

Healthcare is a major global industry accounting for a significant proportion of government spending. Drug and medical device manufacturers are publicly traded companies with a responsibility to their shareholders to maximise profits by increasing sa... Read More about Industry influence in healthcare harms patients: myth or maxim?.

Exploring the challenges of accessing medication for patients with cystic fibrosis (2021)
Journal Article
Herbert, S., Rowbotham, N., Smith, S., Wilson, P., Elliott, Z., Leighton, P., …Smyth, A. R. (2022). Exploring the challenges of accessing medication for patients with cystic fibrosis. Thorax, 77(3), 295-297. https://doi.org/10.1136/thoraxjnl-2021-217140

Reducing treatment burden in cystic fibrosis (CF) is the top research priority for patients and clinicians. Difficulty accessing medication is one aspect of treatment burden. We investigated this with an online survey available globally for patients... Read More about Exploring the challenges of accessing medication for patients with cystic fibrosis.

How can we relieve gastrointestinal symptoms in people with cystic fibrosis? An international qualitative survey (2020)
Journal Article
Smith, S., Rowbotham, N., Davies, G., Gathercole, K., Collins, S. J., Elliott, Z., …Smyth, A. (2020). How can we relieve gastrointestinal symptoms in people with cystic fibrosis? An international qualitative survey. BMJ Open Respiratory Research, 7(1), Article e000614. https://doi.org/10.1136/bmjresp-2020-000614

Introduction Relieving gastrointestinal (GI) symptoms was identified as a ‘top ten’ priority by our James Lind Alliance Priority Setting Partnership in cystic fibrosis (CF). We conducted an online survey to find out more about the effect of GI sympto... Read More about How can we relieve gastrointestinal symptoms in people with cystic fibrosis? An international qualitative survey.

Can exercise replace airway clearance techniques in cystic fibrosis? A survey of patients and healthcare professionals (2019)
Journal Article
Rowbotham, N., Smith, S., Davies, G., Daniels, T., Elliott, Z., Gathercole, K., …Smyth, A. (2020). Can exercise replace airway clearance techniques in cystic fibrosis? A survey of patients and healthcare professionals. Journal of Cystic Fibrosis, 19(4), e19-e24. https://doi.org/10.1016/j.jcf.2019.10.026

Airway clearance techniques (ACTs) are recommended in cystic fibrosis (CF) to prevent accumulation of secretions and lung infection. “Can exercise replace chest physiotherapy for people with CF?” is one of the CF community's top 10 research questions... Read More about Can exercise replace airway clearance techniques in cystic fibrosis? A survey of patients and healthcare professionals.

Do current clinical trials in cystic fibrosis match the priorities of patients and clinicans? A systematic review (2019)
Journal Article
Kalaitzis, I., Rowbotham, N., Smith, S., & Smyth, A. (2019). Do current clinical trials in cystic fibrosis match the priorities of patients and clinicans? A systematic review. Journal of Cystic Fibrosis, https://doi.org/10.1016/j.jcf.2019.06.005

There are many uncertainties regarding Cystic Fibrosis (CF) treatment. Recently, the first James Lind Alliance (JLA) Priority Setting Partnership (PSP) in CF was completed, bringing clinicians, patients and carers together to identify the Top 10 rese... Read More about Do current clinical trials in cystic fibrosis match the priorities of patients and clinicans? A systematic review.

Infection prevention and control in cystic fibrosis: a systematic review of interventions (2019)
Journal Article
Rowbotham, N. J., Palser, S. C., Smith, S. J., & Smyth, A. R. (2019). Infection prevention and control in cystic fibrosis: a systematic review of interventions. Expert Review of Respiratory Medicine, 13(5), 425-434. https://doi.org/10.1080/17476348.2019.1595594

Introduction: Cystic fibrosis is a life-limiting genetic condition characterized by recurrent pulmonary infection. Acquisition of infection can occur from environmental reservoirs, person-to-person transmission and from the healthcare environment. Pr... Read More about Infection prevention and control in cystic fibrosis: a systematic review of interventions.

The top 10 research priorities in cystic fibrosis developed by a partnership between people with CF and health care providers (2017)
Journal Article
Rowbotham, N. J., Smith, S., Leighton, P., Rayner, O. C., Gathercole, K., Elliott, Z., …Smyth, A. R. (2018). The top 10 research priorities in cystic fibrosis developed by a partnership between people with CF and health care providers. Thorax, 73(4), 388-390. https://doi.org/10.1136/thoraxjnl-2017-210473

There remain many treatment uncertainties in cystic fibrosis (CF). With limited resources, research should focus on questions which are most important to the CF community. We conducted a James Lind Alliance Priority Setting Partnership in CF. Researc... Read More about The top 10 research priorities in cystic fibrosis developed by a partnership between people with CF and health care providers.

A systematic review to identify how the current clinical trials landscape reflects the James Lind Alliance top 10 research priorities for cystic fibrosis
Other
Kalaitzis, I., Rowbotham, N. J., Smith, S., & Smyth, A. A systematic review to identify how the current clinical trials landscape reflects the James Lind Alliance top 10 research priorities for cystic fibrosis

This is a protocol to describe the methodology for a systematic review of clinical trials registries to identify intervention trials in the treatment of CF and map them to priorities for CF research.