Outputs (141)

The efficacy of unsupervised home-based exercise regimens in comparison to supervised lab-based exercise training upon cardio-respiratory health facets (2017)
Journal Article
Blackwell, J., Atherton, P. J., Smith, K., Doleman, B., Williams, J. P., Lund, J. N., & Phillips, B. E. (2017). The efficacy of unsupervised home-based exercise regimens in comparison to supervised lab-based exercise training upon cardio-respiratory health facets. Physiological Reports, 5(16), Article e13390. https://doi.org/10.14814/phy2.13390

Supervised high-intensity interval training (HIIT) can rapidly improve cardiorespiratory fitness (CRF). However, the effectiveness of time-efficient unsupervised home-based interventions is unknown. Eighteen volunteers completed either: laboratory-HI... Read More about The efficacy of unsupervised home-based exercise regimens in comparison to supervised lab-based exercise training upon cardio-respiratory health facets.

Alcohol consumption and risk of common cancers: evidence from a cohort of adults from the United Kingdom (2017)
Journal Article
Betts, G., Ratschen, E., Opazo-Breton, M., & Grainge, M. J. (2018). Alcohol consumption and risk of common cancers: evidence from a cohort of adults from the United Kingdom. Journal of Public Health, 40(3), 540–548. https://doi.org/10.1093/pubmed/fdx123

Background: Recent guidelines from the United Kingdom recommend that men and women should drink no more than 14 units of alcohol per week. This recommendation takes into account the link between alcohol and several cancers; however, there is a dearth... Read More about Alcohol consumption and risk of common cancers: evidence from a cohort of adults from the United Kingdom.

Experience of self-harm and its treatment in looked-after young people: an interpretative phenomenological analysis (2017)
Journal Article
Wadman, R., Armstrong, M., Clarke, D., Harroe, C., Majumder, P., Sayal, K., Vostanis, P., & Townsend, E. (in press). Experience of self-harm and its treatment in looked-after young people: an interpretative phenomenological analysis. Archives of Suicide Research, 22(3), https://doi.org/10.1080/13811118.2017.1355286

Objectives: We report the first Interpretative Phenomenological Analysis examination of self-harm and experience of clinical services in young people in the public care system. Methods: Qualitative interviews with 24 looked-after young people. Result... Read More about Experience of self-harm and its treatment in looked-after young people: an interpretative phenomenological analysis.

Association of the resolvin precursor 17-HDHA, but not D- or E- series resolvins, with heat pain sensitivity and osteoarthritis pain in humans (2017)
Journal Article
Valdes, A. M., Ravipati, S., Menni, C., Abhishek, A., Metrustry, S., Harris, J., Nessa, A., Williams, F. M., Spector, T. D., Doherty, M., Chapman, V., & Barrett, D. A. (in press). Association of the resolvin precursor 17-HDHA, but not D- or E- series resolvins, with heat pain sensitivity and osteoarthritis pain in humans. Scientific Reports, 7, Article 10748. https://doi.org/10.1038/s41598-017-09516-3

Resolvins are omega-3 fatty acid derived potent bioactive lipids that resolve inflammation and modulate transient receptor potential channels. Exogenous administration of the resolvin precursor 17-HDHA shows a strong analgesic effect in animal models... Read More about Association of the resolvin precursor 17-HDHA, but not D- or E- series resolvins, with heat pain sensitivity and osteoarthritis pain in humans.

Assessing the impact of the introduction of an electronic hospital discharge system on the completeness and timeliness of discharge communication: a before and after study (2017)
Journal Article
Mehta, R., Baxendale, B., Roth, K., Caswell, V., Le Jeune, I., Hawkins, J., Zedan, H. S., & Avery, A. J. (2017). Assessing the impact of the introduction of an electronic hospital discharge system on the completeness and timeliness of discharge communication: a before and after study. BMC Health Services Research, 17, Article 624. https://doi.org/10.1186/s12913-017-2579-3

Background:


Hospital discharge summaries are a key communication tool ensuring continuity of care between primary and secondary care. Incomplete or untimely communication of information increases risk of hospital readmission and associated compl... Read More about Assessing the impact of the introduction of an electronic hospital discharge system on the completeness and timeliness of discharge communication: a before and after study.

A Neural Basis for Contagious Yawning (2017)
Journal Article
Brown, B. J., Kim, S., Saunders, H., Bachmann, C., Thompson, J., Ropar, D., Jackson, S. R., & Jackson, G. M. (2017). A Neural Basis for Contagious Yawning. Current Biology, 27(17), 2713-2717.e2. https://doi.org/10.1016/j.cub.2017.07.062

Contagious yawning, in which yawning is triggered involuntarily when we observe another person yawn, is a common form of echophenomena—the automatic imitation of another’s words (echolalia) or actions (echopraxia) [1]. The neural basis for echophenom... Read More about A Neural Basis for Contagious Yawning.

Development of a method for determining binaural sensitivity to temporal fine structure (2017)
Journal Article
Füllgrabe, C., Harland, A. J., Sęk, A. P., & Moore, B. C. (2017). Development of a method for determining binaural sensitivity to temporal fine structure. International Journal of Audiology, https://doi.org/10.1080/14992027.2017.1366078

Objective: To develop and evaluate a test of the ability to process binaural temporal-fine-structure (TFS) information. The test was intended to provide a graded measure of TFS sensitivity for all listeners. Design: Sensitivity to TFS was assessed at... Read More about Development of a method for determining binaural sensitivity to temporal fine structure.

Genome-wide association and functional studies identify a role for matrix Gla protein in osteoarthritis of the hand (2017)
Journal Article
Hollander, W. D., Boer, C. G., Hart, D. J., Yau, M. S., Ramos, Y. F., Metrustry, S., Broer, L., Deelen, J., Cupples, L. A., Rivadeneira, F., Kloppenburg, M., Peters, M., Spector, T. D., Hofman, A., Slagboom, P. E., Nelissen, R. G., Uitterlinden, A. G., Felson, D. T., Valdes, A. M., Meulenbelt, I., & van Meurs, J. J. (2017). Genome-wide association and functional studies identify a role for matrix Gla protein in osteoarthritis of the hand. Annals of the Rheumatic Diseases, https://doi.org/10.1136/annrheumdis-2017-211214

Objective Osteoarthritis (OA) is the most common form of arthritis and the leading cause of disability in the elderly. Of all the joints, genetic predisposition is strongest for OA of the hand; however, only few genetic risk loci for hand OA have bee... Read More about Genome-wide association and functional studies identify a role for matrix Gla protein in osteoarthritis of the hand.

The views of children and young people on the use of silk garments for the treatment of eczema: a nested qualitative study within the CLOTHES randomised controlled trial (2017)
Journal Article
Wake, E., Batchelor, J. M., Lawton, S., Thomas, K., Harrison, E. F., & Cowdell, F. (2018). The views of children and young people on the use of silk garments for the treatment of eczema: a nested qualitative study within the CLOTHES randomised controlled trial. British Journal of Dermatology, 178(1), 183-190. https://doi.org/10.1111/bjd.15909

Background: Many children suffer with skin diseases, but to date, most dermatological research has been done ‘on’ rather than ‘with’ children; in this study we actively sought the experiences of children and young people. Atopic eczema (AE) is a chro... Read More about The views of children and young people on the use of silk garments for the treatment of eczema: a nested qualitative study within the CLOTHES randomised controlled trial.

Antibody mediated targeting of the FGFR1c isoform increases glucose uptake in white and brown adipose tissue in male mice (2017)
Journal Article
Lewis, J. E., Samms, R. J., Cooper, S., Luckett, J. C., Perkins, A. C., Dunbar, J. D., Smith, D. P., Emmerson, P. J., Adams, A. C., Ebling, F. J., & Tsintzas, K. (2017). Antibody mediated targeting of the FGFR1c isoform increases glucose uptake in white and brown adipose tissue in male mice. Endocrinology, 158(10), 3090–3096. https://doi.org/10.1210/en.2017-00591

The increased prevalence of obesity and its cardiometabolic implications demonstrates the imperative to identify novel therapeutic targets able to effect meaningful metabolic changes in this population. Antibody-mediated targeting of fibroblast growt... Read More about Antibody mediated targeting of the FGFR1c isoform increases glucose uptake in white and brown adipose tissue in male mice.