Outputs (837)

Interruption to antiplatelet therapy early after acute ischaemic stroke: a nested case-control study (2017)
Journal Article
Mazlan-Kepli, W., Macisaac, R. L., Walters, M., Bath, P. M. W., & Dawson, J. (2017). Interruption to antiplatelet therapy early after acute ischaemic stroke: a nested case-control study. British Journal of Clinical Pharmacology, 83(9), https://doi.org/10.1111/bcp.13290

Aims: Antiplatelet drugs are often discontinued early after ischaemic stroke, either because of poor compliance, complications or withdrawal of care. It is unclear whether this places patients at increased risk of recurrence. We explored the associat... Read More about Interruption to antiplatelet therapy early after acute ischaemic stroke: a nested case-control study.

The impact of laparoscopic ovarian drilling on AMH and ovarian reserve: a meta-analysis (2017)
Journal Article
Amer, S. A., Shamy, T. T. E., James, C., Yosef, A. H., & Mohamed, A. A. (2017). The impact of laparoscopic ovarian drilling on AMH and ovarian reserve: a meta-analysis. Reproduction, 154(1), R13-R21. https://doi.org/10.1530/REP-17-0063

Laparoscopic ovarian drilling (LOD) has been widely used as an effective treatment of anovulatory women with polycystic ovarian syndrome (PCOS). However, there has been a growing concern over a possible damaging effect of this procedure on ovarian re... Read More about The impact of laparoscopic ovarian drilling on AMH and ovarian reserve: a meta-analysis.

The role of CB1 in intestinal permeability and inflammation (2017)
Journal Article
Karwad, M. A., Couch, D. G., Theophilidou, E., Sarmad, S., Barrett, D. A., Larvin, M., Wright, K. L., Lund, J. N., & O'Sullivan, S. (2017). The role of CB1 in intestinal permeability and inflammation. FASEB Journal, 31(8), 3267-3277. https://doi.org/10.1096/fj.201601346R

The endocannabinoid system has previously been shown to play a role in the permeability and inflammatory response of the human gut. The goal of our study was to determine the effects of endogenous anandamide (AEA) and 2-arachidonoyl glycerol (2-AG) o... Read More about The role of CB1 in intestinal permeability and inflammation.

Antipsychotic treatment resistance in first-episode psychosis: prevalence, subtypes and predictors (2017)
Journal Article
Demjaha, A., Demjaha, A., Lappin, J. M., Stahl, D., Patel, M. X., MacCabe, J. H., Howes, O. D., Heslin, M., Reininghaus, U. A., Donoghue, K., Lomas, B., Charalambides, M., Onyejiaka, A., Fearon, P., Jones, P., Doody, G., Morgan, C., Dazzan, P., & Murray, R. M. (2017). Antipsychotic treatment resistance in first-episode psychosis: prevalence, subtypes and predictors. Psychological Medicine, 47(11), 1981-1989. https://doi.org/10.1017/S0033291717000435

Background: We examined longitudinally the course and predictors of treatment resistance in a large cohort of first-episode psychosis (FEP) patients from initiation of antipsychotic treatment. We hypothesized that antipsychotic treatment resistance i... Read More about Antipsychotic treatment resistance in first-episode psychosis: prevalence, subtypes and predictors.

Vision zero: from accident prevention to the promotion of health, safety and well-being at work (2017)
Journal Article
Zwetsloot, G., Leka, S., & Kines, P. (in press). Vision zero: from accident prevention to the promotion of health, safety and well-being at work. Policy and Practice in Health and Safety, 15(2), https://doi.org/10.1080/14773996.2017.1308701

There is growing attention in industry for the Vision Zero strategy, which in terms of work-related health and safety is often labelled as Zero Accident Vision or Zero Harm. The consequences of a genuine commitment to Vision Zero for addressing healt... Read More about Vision zero: from accident prevention to the promotion of health, safety and well-being at work.

Does trajectory matter? A study looking into the relationship of trajectory with target engagement and error accommodation in subthalamic nucleus deep brain stimulation (2017)
Journal Article
Steel, D. A., & Basu, S. (in press). Does trajectory matter? A study looking into the relationship of trajectory with target engagement and error accommodation in subthalamic nucleus deep brain stimulation. Acta Neurochirurgica, https://doi.org/10.1007/s00701-017-3151-y

Background: STN-DBS is now a key treatment choice for advanced Parkinson’s disease. The optimum target area within the STN is well established. However, no emphasis on the impact of trajectory exists. The ellipsoid shape of the STN and the off-centre... Read More about Does trajectory matter? A study looking into the relationship of trajectory with target engagement and error accommodation in subthalamic nucleus deep brain stimulation.

Exploring barriers to South Asian help-seeking for eatingdisorders (2017)
Journal Article
Wales, J., Brewin, N., Raghavan, R., & Arcelus, J. (2017). Exploring barriers to South Asian help-seeking for eatingdisorders. Mental Health Review Journal, 22(1), 40-50. https://doi.org/10.1108/MHRJ-09-2016-0017

Purpose: Referrals to specialist eating disorder (ED) services from the South Asian (SA) community are under-represented, despite research suggesting that disordered eating attitudes and behaviours of SA people are similar to the population in genera... Read More about Exploring barriers to South Asian help-seeking for eatingdisorders.

Evaluating implementation of a fire-prevention injury prevention briefing in children's centres: cluster randomised controlled trial (2017)
Journal Article
Deave, T., Hawkins, A., Kumar, A., Hayes, M., Cooper, N., Watson, M., Ablewhite, J., Coupland, C., Sutton, A., Majsak-Newman, G., McDaid, L., Goodenough, T., Beckett, K., McColl, E., Reading, R., & Kendrick, D. (2017). Evaluating implementation of a fire-prevention injury prevention briefing in children's centres: cluster randomised controlled trial. PLoS ONE, 12(3), Article e0172584. https://doi.org/10.1371/journal.pone.0172584

Background: Many developed countries have high mortality rates for fire-related deaths in children aged 0–14 years with steep social gradients. Evidence-based interventions to promote fire safety practices exist, but the impact of implementing a rang... Read More about Evaluating implementation of a fire-prevention injury prevention briefing in children's centres: cluster randomised controlled trial.

Directed differentiation of human induced pluripotent stem cells into functional cholangiocyte-like cells (2017)
Journal Article
Sampaziotis, F., de Brito, M. C., Geti, I., Bertero, A., Hannan, N. R., & Vallier, L. (2017). Directed differentiation of human induced pluripotent stem cells into functional cholangiocyte-like cells. Nature Protocols, 12(4), 814-827. https://doi.org/10.1038/nprot.2017.011

The difficulty in isolating and propagating functional primary cholangiocytes is a major limitation in the study of biliary disorders and the testing of novel therapeutic agents. To overcome this problem, we have developed a platform for the differen... Read More about Directed differentiation of human induced pluripotent stem cells into functional cholangiocyte-like cells.

Gene expression of inflammatory markers in adipose tissue between obese women with polycystic ovary and normal obese women (2017)
Journal Article
Alshammari, G., Khan, R., Brameld, J. M., Amer, S. A., & Lomax, M. A. (2017). Gene expression of inflammatory markers in adipose tissue between obese women with polycystic ovary and normal obese women. European Review for Medical and Pharmacological Sciences, 21(5),

OBJECTIVE: The pathogenesis of polycystic ovary syndrome (PCOS), a common endocrine disease and metabolic disturbance, is still unknown. The aim of the study was to investigate whether patients with PCOS display increased expression of inflammatory m... Read More about Gene expression of inflammatory markers in adipose tissue between obese women with polycystic ovary and normal obese women.