Zebrafish model for functional screening of flow-responsive genes controlling endothelial cell proliferation
(2024)
Journal Article
Bowley, G., Irving, S., Hoefer, I., Wilkinson, R., Pasterkamp, G., Darwish, H. M. S., White, S., Francis, S. E., Chico, T., Noel, E., Serbanovic-Canic, J., & Evans, P. C. (2024). Zebrafish model for functional screening of flow-responsive genes controlling endothelial cell proliferation. Scientific Reports, 14, Article 30130. https://doi.org/10.1038/s41598-024-77370-1
Local haemodynamics control arterial homeostasis and dysfunction by generating wall shear stress (WSS) which regulates endothelial cell (EC) physiology. Here we use a zebrafish model to identify genes that regulate EC proliferation in response to flo... Read More about Zebrafish model for functional screening of flow-responsive genes controlling endothelial cell proliferation.