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Outputs (2)

Global co-regulatory cross talk between m6A and m5C RNA methylation systems coordinate cellular responses and brain disease pathways (2024)
Journal Article
Orji, O. C., Stones, J., Rajani, S., Markus, R., Demirbugen Öz, M., & Knight, H. M. (2024). Global co-regulatory cross talk between m6A and m5C RNA methylation systems coordinate cellular responses and brain disease pathways. Molecular Neurobiology, https://doi.org/10.1007/s12035-024-04555-0

N6 adenosine and C5 cytosine modification of mRNAs, tRNAs and rRNAs are regulated by the behaviour of distinct sets of writer, reader and eraser effector proteins which are conventionally considered to function independently. Here, we provide evidenc... Read More about Global co-regulatory cross talk between m6A and m5C RNA methylation systems coordinate cellular responses and brain disease pathways.

The expanding role of cap-adjacent modifications in animals (2024)
Journal Article
Bellows, E., Fray, R. G., Knight, H. M., & Archer, N. (2024). The expanding role of cap-adjacent modifications in animals. Frontiers in RNA Research, 2, Article 1485307. https://doi.org/10.3389/frnar.2024.1485307

Eukaryotic mRNA cap structures directly influence mRNA stability, translation, and immune recognition. While the significance of the mRNA cap itself has been well-established, recent research has revealed the intricate modifications to the nucleotide... Read More about The expanding role of cap-adjacent modifications in animals.