Spatiotemporal immunolocalisation of REST in the brain of healthy ageing and Alzheimer’s disease rats
(2020)
Journal Article
Mampay, M., Velasco‐Estevez, M., Rolle, S. O., Chaney, A. M., Boutin, H., Dev, K. K., Moeendarbary, E., & Sheridan, G. K. (2021). Spatiotemporal immunolocalisation of REST in the brain of healthy ageing and Alzheimer’s disease rats. FEBS Open Bio, 11(1), 146-163. https://doi.org/10.1002/2211-5463.13036
In the brain, REST (Repressor Element‐1 Silencing Transcription factor) is a key regulator of neuron cell‐specific gene expression. Nuclear translocation of neuronal REST has been shown to be neuroprotective in a healthy ageing context. In contrast,... Read More about Spatiotemporal immunolocalisation of REST in the brain of healthy ageing and Alzheimer’s disease rats.