Outputs (3)

Deconditioning in quiescent Crohn’s Disease patients with heightened fatigue perception (2025)
Journal Article
McGing, J. J., Serres, S., Nicholas, R., Gupta, A., Radford, S. J., Nixon, A. V., Mallinson, J., Bradley, C., Bawden, S., Francis, S. T., Greenhaff, P. L., & Moran, G. W. (2025). Deconditioning in quiescent Crohn’s Disease patients with heightened fatigue perception. Journal of Crohn's and Colitis, 19(1), Article jjae194. https://doi.org/10.1093/ecco-jcc/

Background & Objective

IBD fatigue aetiology is poorly understood. This study quantified body composition and physical function alongside proton magnetic resonance imaging (1H MRI) and spectroscopy (31P MRS) measures of organ structure and functio... Read More about Deconditioning in quiescent Crohn’s Disease patients with heightened fatigue perception.

Bed‐rest and exercise remobilization: Concurrent adaptations in muscle glucose and protein metabolism (2024)
Journal Article
Shur, N. F., Simpson, E. J., Crossland, H., Constantin, D., Cordon, S. M., Constantin-Teodosiu, D., Stephens, F. B., Brook, M. S., Atherton, P. J., Smith, K., Wilkinson, D. J., Mougin, O. E., Bradley, C., Macdonald, I. A., & Greenhaff, P. L. (2024). Bed‐rest and exercise remobilization: Concurrent adaptations in muscle glucose and protein metabolism. Journal of Cachexia, Sarcopenia and Muscle, 15(2), 603-614. https://doi.org/10.1002/jcsm.13431

Background
Bed-rest (BR) of only a few days duration reduces muscle protein synthesis and induces skeletal muscle atrophy and insulin resistance, but the scale and juxtaposition of these events have not been investigated concurrently in the same ind... Read More about Bed‐rest and exercise remobilization: Concurrent adaptations in muscle glucose and protein metabolism.

The haemodynamics of the human placenta in utero (2020)
Journal Article
Dellschaft, N. S., Hutchinson, G., Shah, S., Jones, N. W., Bradley, C., Leach, L., Platt, C., Bowtell, R., & Gowland, P. A. (2020). The haemodynamics of the human placenta in utero. PLoS Biology, 18(5), Article e3000676. https://doi.org/10.1371/journal.pbio.3000676

© 2020 Dellschaft et al. We have used magnetic resonance imaging (MRI) to provide important new insights into the function of the human placenta in utero. We have measured slow net flow and high net oxygenation in the placenta in vivo, which are cons... Read More about The haemodynamics of the human placenta in utero.