Outputs (14)

Modulation of the biological response to surfaces through the controlled deposition of 3D polymeric surfactants (2025)
Journal Article
Cuzzucoli Crucitti, V., Hajiali, H., Dundas, A. A., Jayawarna, V., Tomolillo, D., Francolini, I., Vuotto, C., Salmeron-Sanchez, M., Dalby, M. J., Alexander, M. R., Wildman, R. D., Rose, F. R. A. J., & Irvine, D. J. (2025). Modulation of the biological response to surfaces through the controlled deposition of 3D polymeric surfactants. Journal of Materials Chemistry B, 13(15), 4657-4670. https://doi.org/10.1039/d4tb01941e

Biomaterials play a crucial role in modern medicine through their use as medical implants and devices. However, they can support biofilm formation and infection, and lack integration with the surrounding human tissue at the implant site. This work re... Read More about Modulation of the biological response to surfaces through the controlled deposition of 3D polymeric surfactants.

Rapid, Highly Sustainable Ring-Opening Polymerization via Resonant Acoustic Mixing (2025)
Journal Article
Fowler, H. R., O’Shea, R., Sefton, J., Howard, S. C., Muir, B. W., Stockman, R. A., Taresco, V., & Irvine, D. J. (2025). Rapid, Highly Sustainable Ring-Opening Polymerization via Resonant Acoustic Mixing. ACS Sustainable Chemistry and Engineering, 13(5), 1916–1926. https://doi.org/10.1021/acssuschemeng.4c06330

Reported herein is the first combination of resonant acoustic mixing (RAM) and controlled ring-opening polymerization (ROP) to deliver fully sustainable, end-functionalized, biodegradable polymers via a manufacturing route with a much-reduced environ... Read More about Rapid, Highly Sustainable Ring-Opening Polymerization via Resonant Acoustic Mixing.

Dielectrically Monitored Flow Synthesis of Functional Vaccine Adjuvant Mixtures via Microwave-Assisted Catalytic Chain Transfer Processing (2025)
Journal Article
Hege, C. S., Hamilton, I. E., Dundas, A. A., Adlington, K., Walker, E., Henke, H., Wang, K., Dimitrakis, G., Buttress, A., Dodds, C., Fox, C. B., & Irvine, D. J. (2025). Dielectrically Monitored Flow Synthesis of Functional Vaccine Adjuvant Mixtures via Microwave-Assisted Catalytic Chain Transfer Processing. Chemistry, 7(1), Article 10. https://doi.org/10.3390/chemistry7010010

A novel flow process to produce low-molecular-weight (Mwt) methacrylate oligomer mixtures that have potential as vaccine adjuvants and chain transfer agents (CTAs) is reported. The chemistry and process were designed to significantly reduce the numbe... Read More about Dielectrically Monitored Flow Synthesis of Functional Vaccine Adjuvant Mixtures via Microwave-Assisted Catalytic Chain Transfer Processing.

Development of C. albican Anti-attachment Inkjet 3D Printing Ink, via High Throughput Screening (2025)
Presentation / Conference Contribution
Yong, L. X., Zhou, Z., Vallières, C., He, Y., Cuzzucoli Crucitti, V., Alexander, M. R., Avery, S., Wildman, R., & Irvine, D. (2024, August). Development of C. albican Anti-attachment Inkjet 3D Printing Ink, via High Throughput Screening. Presented at International Conference on Computational & Experimental Engineering and Sciences, Singapore, Singapore

The fungal pathogen Candida albicans (C. albicans) is particularly problematic for immunocompromised patients and those with medical implants. Introducing Candida-resistant medical devices could potentially reduce mortality rates from such infections... Read More about Development of C. albican Anti-attachment Inkjet 3D Printing Ink, via High Throughput Screening.

Towards a scalable cacao pod husk biorefinery: Understanding the effects of process conditions on phenolic antioxidant extraction and residual solid properties (2024)
Journal Article
Dewi, S. R., Stevens, L. A., Anwar, M., Mao, Y., Ferrari, R. S., Irvine, D. J., & Binner, E. R. (2025). Towards a scalable cacao pod husk biorefinery: Understanding the effects of process conditions on phenolic antioxidant extraction and residual solid properties. Chemical Engineering Science, 305, Article 121171. https://doi.org/10.1016/j.ces.2024.121171

Cacao pod husk (CPH) is a potential source of phenolic-based antioxidants and lignocellulosic compounds. Sample pretreatments and extraction conditions were investigated to understand their effects on extraction yields and implications for industrial... Read More about Towards a scalable cacao pod husk biorefinery: Understanding the effects of process conditions on phenolic antioxidant extraction and residual solid properties.

High resolution 3D printed biocatalytic reactor core with optimized efficiency for continuous flow synthesis (2024)
Journal Article
Attwood, S. J., Leech, D., He, Y., Croft, A., Hague, R. J., Irvine, D. J., Wildman, R. D., & Pordea, A. (2025). High resolution 3D printed biocatalytic reactor core with optimized efficiency for continuous flow synthesis. Chemical Engineering Science, 305, Article 121156. https://doi.org/10.1016/j.ces.2024.121156

3D printing has the potential to transform biocatalytic continuous flow reactor technology, where precise control of topology is essential for maximizing reactor performance. By embedding enzymatic catalysts in polymer hydrogel networks, continuous s... Read More about High resolution 3D printed biocatalytic reactor core with optimized efficiency for continuous flow synthesis.

Additive manufacture of complex 3D Au-containing nanocomposites by simultaneous two-photon polymerisation and photoreduction (2017)
Journal Article
Parmenter, C. D. J., Hu, Q., Sun, X. Z., Parmenter, C. D., Fay, M. W., Smith, E. F., Rance, G. A., He, Y., Zhang, F., Liu, Y., Irvine, D., Tuck, C., Hague, R., & Wildman, R. (2017). Additive manufacture of complex 3D Au-containing nanocomposites by simultaneous two-photon polymerisation and photoreduction. Scientific Reports, 7(1), Article 17150. https://doi.org/10.1038/s41598-017-17391-1

© 2017 The Author(s). The fabrication of complex three-dimensional gold-containing nanocomposite structures by simultaneous two-photon polymerisation and photoreduction is demonstrated. Increased salt delivers reduced feature sizes down to line width... Read More about Additive manufacture of complex 3D Au-containing nanocomposites by simultaneous two-photon polymerisation and photoreduction.

Selective molecular annealing: in situ small angle X-ray scattering study of microwave-assisted annealing of block copolymers (2017)
Journal Article
Toolan, D. T., Adlington, K., Isakova, A., Kalamiotis, A., Mokarian-Tabari, P., Dimitrakis, G., Dodds, C., Arnold, T., Terrill, N. J., Bras, W., Hermida Merino, D., Topham, P. D., Irvine, D., & Howse, J. R. (2017). Selective molecular annealing: in situ small angle X-ray scattering study of microwave-assisted annealing of block copolymers. Physical Chemistry Chemical Physics, 19(31), 20412--20419. https://doi.org/10.1039/c7cp03578k

Microwave annealing has emerged as an alternative to traditional thermal annealing approaches for optimising block copolymer self-assembly. A novel sample environment enabling small angle X-ray scattering to be performed in situ during microwave anne... Read More about Selective molecular annealing: in situ small angle X-ray scattering study of microwave-assisted annealing of block copolymers.

Wet and dry flexural high cycle fatigue behaviour of fully bioresorbable glass fibre composites: In-situ polymerisation versus laminate stacking (2017)
Journal Article
Chen, M., Lu, J., Felfel, R. M., Parsons, A. J., Irvine, D. J., Rudd, C. D., & Ahmed, I. (2017). Wet and dry flexural high cycle fatigue behaviour of fully bioresorbable glass fibre composites: In-situ polymerisation versus laminate stacking. Composites Science and Technology, 150, 1-15. https://doi.org/10.1016/j.compscitech.2017.07.006

Fully bioresorbable phosphate based glass fibre reinforced polycaprolactone (PCL/PGF) composites are potentially excellent candidates to address current issues experienced with use of metal implants for hard tissue repair, such as stress shielding ef... Read More about Wet and dry flexural high cycle fatigue behaviour of fully bioresorbable glass fibre composites: In-situ polymerisation versus laminate stacking.

Exemplification of catalyst design for microwave selective heating and its application to efficient in situ catalyst synthesis (2017)
Journal Article
Wang, K., Dimitrakis, G., & Irvine, D. J. (2017). Exemplification of catalyst design for microwave selective heating and its application to efficient in situ catalyst synthesis. Chemical Engineering and Processing: Process Intensification, 122, https://doi.org/10.1016/j.cep.2017.01.012

The use of dielectric spectroscopy to develop an underpinning understanding of the molecular transformations involved in achieving the successful, rapid in situ synthesis of a catalytic chain transfer polymerisation (CCTP) catalyst using microwave he... Read More about Exemplification of catalyst design for microwave selective heating and its application to efficient in situ catalyst synthesis.