Outputs (21)

Conformational analysis and interaction of the Staphylococcus aureus transmembrane peptidase AgrB with its AgrD propeptide substrate (2023)
Journal Article
Bardelang, P., Murray, E. J., Blower, I., Zandomeneghi, S., Goode, A., Hussain, R., …Bonev, B. B. (2023). Conformational analysis and interaction of the Staphylococcus aureus transmembrane peptidase AgrB with its AgrD propeptide substrate. Frontiers in Chemistry, 11, Article 1113885. https://doi.org/10.3389/fchem.2023.1113885

Virulence gene expression in the human pathogen, S. aureus is regulated by the agr (accessory gene regulator) quorum sensing (QS) system which is conserved in diverse Gram-positive bacteria. The agr QS signal molecule is an autoinducing peptide (AIP)... Read More about Conformational analysis and interaction of the Staphylococcus aureus transmembrane peptidase AgrB with its AgrD propeptide substrate.

Re-thinking the Mental Capacity Act 2005: Towards the Next Generation of Law (2022)
Journal Article
Bartlett, P. (2023). Re-thinking the Mental Capacity Act 2005: Towards the Next Generation of Law. Modern Law Review, 86(3), 659-700. https://doi.org/10.1111/1468-2230.12774

It is now more than a quarter of a century since the Law Commission completed its ground-breaking report on mental capacity, a report that became the Mental Capacity Act 2005. Since that time, there have been fundamental changes in the legal, social,... Read More about Re-thinking the Mental Capacity Act 2005: Towards the Next Generation of Law.

Insights on conducting digital patient and public involvement in dementia research during the COVID-19 pandemic: supporting the development of an “E-nabling digital co-production” framework (2022)
Journal Article
Molinari-Ulate, M., Woodcock, R., Smith, I., van der Roest, H. G., Franco-Martín, M. A., & Craven, M. P. (2022). Insights on conducting digital patient and public involvement in dementia research during the COVID-19 pandemic: supporting the development of an “E-nabling digital co-production” framework. Research Involvement and Engagement, 8(1), Article 33. https://doi.org/10.1186/s40900-022-00371-9

Background
The rapid transition to digital working, accelerated due to the response to the COVID-19 pandemic, has impacted the involvement of patients and public in research. This paper presents experiences of engaging in digital Patient and Public... Read More about Insights on conducting digital patient and public involvement in dementia research during the COVID-19 pandemic: supporting the development of an “E-nabling digital co-production” framework.

Psychological Impacts of COVID–19 on Healthcare Trainees and Perceptions towards a Digital Wellbeing Support Package (2021)
Journal Article
Blake, H., Mahmood, I., Dushi, G., Yildirim, M., & Gay, E. (2021). Psychological Impacts of COVID–19 on Healthcare Trainees and Perceptions towards a Digital Wellbeing Support Package. International Journal of Environmental Research and Public Health, 18(20), Article 10647. https://doi.org/10.3390/ijerph182010647

We explore the impact of COVID-19 on the psychological wellbeing of healthcare trainees, and the perceived value of a digital support package to mitigate the psychological impacts of the pandemic (PoWerS Study). This mixed–methods study includes (i)... Read More about Psychological Impacts of COVID–19 on Healthcare Trainees and Perceptions towards a Digital Wellbeing Support Package.

Test@work: evaluation of workplace HIV testing for construction workers using the RE-AIM framework (2021)
Journal Article
Jones, W., Somerset, S., Evans, C., Whittingham, K., Middleton, M., & Blake, H. (2021). Test@work: evaluation of workplace HIV testing for construction workers using the RE-AIM framework. BMC Public Health, 21, Article 1737. https://doi.org/10.1186/s12889-021-11739-z

Background: Community testing for HIV can reach previously untested populations but is rarely offered in workplaces. Targeting the construction sector could reach workers from high risk populations. Methods: The RE-AIM framework was used to evaluate... Read More about Test@work: evaluation of workplace HIV testing for construction workers using the RE-AIM framework.

Characterising the outcomes, impacts and implementation challenges of advanced clinical practice roles in the UK: A scoping review (2021)
Journal Article
Evans, C., Poku, B. A., Pearce, R., Eldridge, J., Hendrick, P., Knaggs, R., …Collier, R. (2021). Characterising the outcomes, impacts and implementation challenges of advanced clinical practice roles in the UK: A scoping review. BMJ Open, 11(8), Article e048171. https://doi.org/10.1136/bmjopen-2020-048171

Objectives In response to demographic and health system pressures, the development of non-medical advanced clinical practice (ACP) roles is a key component of National Health Service workforce transformation policy in the UK. This review was undertak... Read More about Characterising the outcomes, impacts and implementation challenges of advanced clinical practice roles in the UK: A scoping review.

Development of a school-based intervention to increase physical activity levels among Chinese children: a systematic iterative process based on Behaviour Change Wheel and Theoretical Domains Framework (2021)
Journal Article
Chattopadhyay, K., Blake, H., & Wang, H. (2021). Development of a school-based intervention to increase physical activity levels among Chinese children: a systematic iterative process based on Behaviour Change Wheel and Theoretical Domains Framework. Frontiers in Public Health, 9, Article 610245. https://doi.org/10.3389/fpubh.2021.610245

Regular physical activity has a range of benefits for children’s health, academic achievement, and behavioral development, yet they face barriers to participation. The aim of the study was to systematically develop an intervention for improving Chine... Read More about Development of a school-based intervention to increase physical activity levels among Chinese children: a systematic iterative process based on Behaviour Change Wheel and Theoretical Domains Framework.

Students’ views towards sars-cov-2 mass asymptomatic testing, social distancing and self-isolation in a university setting during the covid-19 pandemic: A qualitative study (2021)
Journal Article
Blake, H., Knight, H., Jia, R., Corner, J., Morling, J. R., Denning, C., Ball, J. K., Bolton, K., Figeuredo, G., Morris, D., Tighe, P., Villalon, A. M., Ayling, K., & Vedhara, K. (2021). Students’ views towards sars-cov-2 mass asymptomatic testing, social distancing and self-isolation in a university setting during the covid-19 pandemic: A qualitative study . International Journal of Environmental Research and Public Health, 18(8), Article 4182. https://doi.org/10.3390/ijerph18084182

We aimed to explore university students’ perceptions and experiences of SARS-CoV-2 mass asymptomatic testing, social distancing and self-isolation, during the COVID-19 pandemic. This qualitative study comprised of four rapid online focus groups condu... Read More about Students’ views towards sars-cov-2 mass asymptomatic testing, social distancing and self-isolation in a university setting during the covid-19 pandemic: A qualitative study .

Accessing Voluntary HIV Testing in the Construction Industry: A Qualitative Analysis of Employee Interviews from the Test@Work Study (2021)
Journal Article
Somerset, S., Evans, C., & Blake, H. (2021). Accessing Voluntary HIV Testing in the Construction Industry: A Qualitative Analysis of Employee Interviews from the Test@Work Study. International Journal of Environmental Research and Public Health, 18(8), Article 4184. https://doi.org/10.3390/ijerph18084184

HIV, globally, remains a significant public health issue and community HIV testing can help to identify those with HIV at an early stage of disease. The workplace offers a prime location for provision of opt-in HIV testing as part of wider health pro... Read More about Accessing Voluntary HIV Testing in the Construction Industry: A Qualitative Analysis of Employee Interviews from the Test@Work Study.

Covid-well study: Qualitative evaluation of supported wellbeing centres and psychological first aid for healthcare workers during the covid-19 pandemic (2021)
Journal Article
Blake, H., Gupta, A., Javed, M., Wood, B., Knowles, S., Coyne, E., & Cooper, J. (2021). Covid-well study: Qualitative evaluation of supported wellbeing centres and psychological first aid for healthcare workers during the covid-19 pandemic. International Journal of Environmental Research and Public Health, 18(7), Article 3626. https://doi.org/10.3390/ijerph18073626

Supported wellbeing centres were set up in UK hospital trusts as an early intervention aimed at mitigating the psychological impact of COVID-19 on healthcare workers. These provided high quality rest spaces with peer-to-peer psychological support pro... Read More about Covid-well study: Qualitative evaluation of supported wellbeing centres and psychological first aid for healthcare workers during the covid-19 pandemic.

COVID-Well: Evaluation of the Implementation of Supported Wellbeing Centres for Hospital Employees during the COVID-19 Pandemic (2020)
Journal Article
Blake, H., Yildirim, M., Wood, B., Knowles, S., Mancini, H., Coyne, E., & Cooper, J. (2020). COVID-Well: Evaluation of the Implementation of Supported Wellbeing Centres for Hospital Employees during the COVID-19 Pandemic. International Journal of Environmental Research and Public Health, 17(24), 1-22. https://doi.org/10.3390/ijerph17249401

Supported Wellbeing Centres have been set up in UK hospital trusts in an effort to mitigate the psychological impact of COVID-19 on healthcare workers, although the extent to which these are utilised and the barriers and facilitators to access are no... Read More about COVID-Well: Evaluation of the Implementation of Supported Wellbeing Centres for Hospital Employees during the COVID-19 Pandemic.

Test@Work Texts: Mobile Phone Messaging to Increase Awareness of HIV and HIV Testing in UK Construction Employees during the COVID-19 Pandemic (2020)
Journal Article
Middleton, M., Somerset, S., Evans, C., & Blake, H. (2020). Test@Work Texts: Mobile Phone Messaging to Increase Awareness of HIV and HIV Testing in UK Construction Employees during the COVID-19 Pandemic. International Journal of Environmental Research and Public Health, 17(21), Article 7819. https://doi.org/10.3390/ijerph17217819

© 2020 by the authors. Licensee MDPI, Basel, Switzerland. Background: HIV poses a threat to global health. With effective treatment options available, education and testing strategies are essential in preventing transmission. Text messaging is an eff... Read More about Test@Work Texts: Mobile Phone Messaging to Increase Awareness of HIV and HIV Testing in UK Construction Employees during the COVID-19 Pandemic.

SOX9 promotes stress-responsive transcription of VGF nerve growth factor inducible gene in renal tubular epithelial cells (2020)
Journal Article
Kim, J. Y., Bai, Y., Jayne, L. A., Abdulkader, F., Gandhi, M., Perreau, T., …Pabla, N. S. (2020). SOX9 promotes stress-responsive transcription of VGF nerve growth factor inducible gene in renal tubular epithelial cells. Journal of Biological Chemistry, 295(48), 16328-16341. https://doi.org/10.1074/jbc.RA120.015110

© 2020 Kim et al. Acute kidney injury (AKI) is a common clinical condition associated with diverse etiologies and abrupt loss of renal function. In patients with sepsis, rhabdomyolysis, cancer, and cardiovascular disorders, the underlying disease or... Read More about SOX9 promotes stress-responsive transcription of VGF nerve growth factor inducible gene in renal tubular epithelial cells.

WHIRL Study: Workplace Health Interprofessional Learning in the Construction Industry (2020)
Journal Article
Blake, H., Somerset, S., Whittingham, K., Middleton, M., Yildirim, M., & Evans, C. (2020). WHIRL Study: Workplace Health Interprofessional Learning in the Construction Industry. International Journal of Environmental Research and Public Health, 17(18), Article 6815. https://doi.org/10.3390/ijerph17186815

© 2020 by the authors. Licensee MDPI, Basel, Switzerland. Interprofessional learning (IPL) is essential to prepare healthcare trainees as the future public health workforce. WHIRL (Workplace Health InteRprofessional Learning) was an innovative IPL in... Read More about WHIRL Study: Workplace Health Interprofessional Learning in the Construction Industry.

Using Internet of Things to Reduce Office Workers’ Sedentary Behavior: Intervention Development Applying the Behavior Change Wheel and Human-Centered Design Approach (2020)
Journal Article
Huang, Y., Benford, S., Price, D., Patel, R., Li, B., Ivanov, A., & Blake, H. (2020). Using Internet of Things to Reduce Office Workers’ Sedentary Behavior: Intervention Development Applying the Behavior Change Wheel and Human-Centered Design Approach. JMIR mHealth and uHealth, 8(7), Article e17914. https://doi.org/10.2196/17914

Background: Sedentary behavior (SB) is associated with various adverse health outcomes. The prevalence of prolonged sitting at work among office workers makes a case for SB interventions to target this setting and population. Everyday mundane objects... Read More about Using Internet of Things to Reduce Office Workers’ Sedentary Behavior: Intervention Development Applying the Behavior Change Wheel and Human-Centered Design Approach.

COVID-19 And The Provision Of Wobble Rooms And Wellbeing Centres For Healthcare Workers (2020)
Report
Blake, H., & Dennis, M. (2020). COVID-19 And The Provision Of Wobble Rooms And Wellbeing Centres For Healthcare Workers. Florence Nightingale Foundation

A Population-based PBPK Model for the Prediction of Time-Variant Bile Salt Disposition within GI Luminal Fluids (2020)
Journal Article
Stamatopoulos, K., Pathak, S., Marciani, L., & Turner, D. (2020). A Population-based PBPK Model for the Prediction of Time-Variant Bile Salt Disposition within GI Luminal Fluids. Molecular Pharmaceutics, 17(4), 1310-1323. https://doi.org/10.1021/acs.molpharmaceut.0c00019

In vivo studies have shown cyclic bile salt (BS) outputs during fasting whereas higher amounts have been observed in fed states. This leads to fluctuations of intestinal BS concentrations ([BS]) that can affect the rate and extent of absorption of li... Read More about A Population-based PBPK Model for the Prediction of Time-Variant Bile Salt Disposition within GI Luminal Fluids.

Prediction of Stroke Risk by Detection of Hemorrhage in Carotid Plaques: Meta-Analysis of Individual Patient Data (2019)
Journal Article
Schindler, A., Schinner, R., Altaf, N., Hosseini, A. A., Simpson, R. J., Esposito-Bauer, L., …Saam, T. (2019). Prediction of Stroke Risk by Detection of Hemorrhage in Carotid Plaques: Meta-Analysis of Individual Patient Data. JACC: Cardiovascular Imaging, 13(2), 395-406. https://doi.org/10.1016/j.jcmg.2019.03.028

Objectives
The goal of this study was to compare the risk of stroke between patients with carotid artery disease with and without the presence of intraplaque hemorrhage (IPH) on magnetic resonance imaging.

Background
IPH in carotid stenosis incr... Read More about Prediction of Stroke Risk by Detection of Hemorrhage in Carotid Plaques: Meta-Analysis of Individual Patient Data.

Tactical authenticity in the production of mad narratives (2019)
Journal Article
WRIGHT, C., & CLARKE, S. (2019). Tactical authenticity in the production of mad narratives. Social Theory and Health, 17(2), 15. https://doi.org/10.1057/s41285-019-00092-2

First-person accounts of madness and of encountering psychiatric services provide important sociocultural and psychological knowledge about the subjectivity of distress. The importance of such accounts is often based upon a claim of the authenticity... Read More about Tactical authenticity in the production of mad narratives.

The Self and Others in CFS/ME: Reinterpreting Research Evidence (2015)
Book Chapter
Ward, C. D., & Horrocks, M. (2015). The Self and Others in CFS/ME: Reinterpreting Research Evidence. In Meanings of ME: Interpersonal and Social Dimensions of Chronic Fatigue (106-128). London: Palgrave Macmillan UK. https://doi.org/10.1057/9781137467324_9

Chapter 7 provided interpersonal perspectives on CFS/ME without offering any theoretical commentary. This chapter considers how the meanings of CFS/ ME are developed between individuals and others. We begin with a critique of the cognitive-behavioura... Read More about The Self and Others in CFS/ME: Reinterpreting Research Evidence.