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Strategies for using topical corticosteroids in children and adults with eczema (2022)
Journal Article
Lax, S., Harvey, J., Axon, E., Howells, L., Santer, M., Ridd, M., …Chalmers, J. (2022). Strategies for using topical corticosteroids in children and adults with eczema. Cochrane Database of Systematic Reviews, 3(3), Article CD013356

Background Eczema is a common skin condition. Although topical corticosteroids (TCS) have been a first-line treatment for eczema for decades, there are uncertainties over their optimal use. Objectives To establish the effectiveness and safety of diff... Read More about Strategies for using topical corticosteroids in children and adults with eczema.

Cause‐specific mortality in people with bullous pemphigoid and pemphigus vulgaris: a systematic review and meta‐analysis (2021)
Journal Article
Hasanaj, A., Zaki, F., Harman, K. E., Grindlay, D., & Gran, S. (2022). Cause‐specific mortality in people with bullous pemphigoid and pemphigus vulgaris: a systematic review and meta‐analysis. British Journal of Dermatology, 186(2), 359-361. https://doi.org/10.1111/bjd.20759

Bullous pemphigoid (BP) and pemphigus vulgaris (PV) are autoimmune blistering skin disorders which are increasing in incidence and are associated with high mortality. 1,2 As people with BP and PV often have comorbidity and require treatment that ha... Read More about Cause‐specific mortality in people with bullous pemphigoid and pemphigus vulgaris: a systematic review and meta‐analysis.

Personalised prediction of daily eczema severity scores using a mechanistic machine learning model (2020)
Journal Article
Hurault, G., Domínguez‐Hüttinger, E., Langan, S. M., Williams, H. C., & Tanaka, R. J. (2020). Personalised prediction of daily eczema severity scores using a mechanistic machine learning model. Clinical and Experimental Allergy, 50(11), 1258-1266. https://doi.org/10.1111/cea.13717

Background Atopic dermatitis (AD) is a chronic inflammatory skin disease with periods of flares and remission. Designing personalised treatment strategies for AD is challenging, given the apparent unpredictability and large variation in AD symptom... Read More about Personalised prediction of daily eczema severity scores using a mechanistic machine learning model.

Daily emollient during infancy for prevention of eczema: the BEEP randomised controlled trial (2020)
Journal Article
Chalmers, J. R., Haines, R. H., Bradshaw, L. E., Montgomery, A. A., Thomas, K. S., Brown, S. J., …Williams, H. C. (2020). Daily emollient during infancy for prevention of eczema: the BEEP randomised controlled trial. Lancet, 395(10228), 962-972. https://doi.org/10.1016/S0140-6736%2819%2932984-8

Background Skin barrier dysfunction precedes eczema development. We tested whether daily use of emollient in the first year could prevent eczema in high-risk children. Methods We did a multicentre, pragmatic, parallel-group, randomised contr... Read More about Daily emollient during infancy for prevention of eczema: the BEEP randomised controlled trial.

A behaviour change package to prevent hand dermatitis in nurses working in health care: the SCIN cluster RCT (2019)
Journal Article
Madan, I., Parsons, V., Ntani, G., Wright, A., English, J., Coggon, D., …Williams, H. (2019). A behaviour change package to prevent hand dermatitis in nurses working in health care: the SCIN cluster RCT. Health Technology Assessment, 23(58), 1-92. https://doi.org/10.3310/hta23580

BACKGROUND: Although strategies have been developed to minimise the risk of occupational hand dermatitis in nurses, their clinical effectiveness and cost-effectiveness remain unclear. OBJECTIVES: The Skin Care Intervention in Nurses trial tested the... Read More about A behaviour change package to prevent hand dermatitis in nurses working in health care: the SCIN cluster RCT.

Interventions to reduce Staphylococcus aureus in the management of eczema (2019)
Journal Article
George, S. M., Karanovic, S., Harrison, D. A., Rani, A., Birnie, A. J., Bath-Hextall, F. J., …Williams, H. C. (2019). Interventions to reduce Staphylococcus aureus in the management of eczema. Cochrane Database of Systematic Reviews, 2019(10), 145. https://doi.org/10.1002/14651858.cd003871.pub3

© 2019 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd. Background Staphylococcus aureus (S. aureus) can cause secondary infection in eczema, and may promote inflammation in eczema that does not look infected. There is no standard i... Read More about Interventions to reduce Staphylococcus aureus in the management of eczema.

Defining and measuring " eczema control " : an international qualitative study to explore the views of those living with and treating atopic eczema (2019)
Journal Article
Howells, L., Thomas, K. S., Sears, A. V., Nasr, I., Wollenberg, A., Schuttelaar, M. L., …Chalmers, J. R. (2019). Defining and measuring " eczema control " : an international qualitative study to explore the views of those living with and treating atopic eczema. Journal of the European Academy of Dermatology and Venereology, 33(6), 1124-1132. https://doi.org/10.1111/jdv.15475

Background: Atopic eczema (also known as eczema) is a chronic, inflammatory skin condition that often afflicts patients’ health and wellbeing. The Harmonising Outcome Measures for Eczema (HOME) initiative recommends that “long-term control of eczema”... Read More about Defining and measuring " eczema control " : an international qualitative study to explore the views of those living with and treating atopic eczema.