Outputs (40)

Macrocyclic transition-metal parashift complexes for MRI at clinical and pre-clinical magnetic fields (2025)
Journal Article
Rogers, N. J., Ashok Kumar, C., Alexander, C., Bowdery, D., Pavlovskaya, G., & Harvey, P. (2025). Macrocyclic transition-metal parashift complexes for MRI at clinical and pre-clinical magnetic fields. Dalton Transactions, 54(28), 11036-11046. https://doi.org/10.1039/d5dt01149c

A series of macrocyclic transition-metal complexes, including Fe(II), Co(II), Ni(II), and Cu(II) complexes, have been evaluated for parashift MRI imaging applications, by assessing their paramagnetic NMR properties, including proton chemical shifts,... Read More about Macrocyclic transition-metal parashift complexes for MRI at clinical and pre-clinical magnetic fields.

Tracking the neurodevelopmental trajectory of beta band oscillations with optically pumped magnetometer-based magnetoencephalography (2024)
Journal Article
Rier, L., Rhodes, N., Pakenham, D. O., Boto, E., Holmes, N., Hill, R. M., Reina Rivero, G., Shah, V., Doyle, C., Osborne, J., Bowtell, R. W., Taylor, M., & Brookes, M. J. (2024). Tracking the neurodevelopmental trajectory of beta band oscillations with optically pumped magnetometer-based magnetoencephalography. eLife, 13, Article RP94561. https://doi.org/10.7554/elife.94561.3

Neural oscillations mediate the coordination of activity within and between brain networks, supporting cognition and behaviour. How these processes develop throughout childhood is not only an important neuroscientific question but could also shed lig... Read More about Tracking the neurodevelopmental trajectory of beta band oscillations with optically pumped magnetometer-based magnetoencephalography.

Swallow Tail Sign: Revisited (2022)
Journal Article
Brammerloh, M., Kirilina, E., Alkemade, A., Bazin, P.-L., Jantzen, C., Jäger, C., Herrler, A., Pine, K. J., Gowland, P. A., Morawski, M., Forstmann, B. U., & Weiskopf, N. (2022). Swallow Tail Sign: Revisited. Radiology, 305(3), 674-677. https://doi.org/10.1148/radiol.212696

The loss of the radiologic swallow tail sign on MRI scans of the substantia nigra is a promising diagnostic marker of Parkinson disease (1), although its anatom-ic underpinning is unclear. An early influential study showed th... Read More about Swallow Tail Sign: Revisited.

Phenotypic and genetic associations of quantitative magnetic susceptibility in UK Biobank brain imaging (2022)
Journal Article
Wang, C., Martins-Bach, A. B., Alfaro-Almagro, F., Douaud, G., Klein, J. C., Llera, A., Fiscone, C., Bowtell, R., Elliott, L. T., Smith, S. M., Tendler, B. C., & Miller, K. L. (2022). Phenotypic and genetic associations of quantitative magnetic susceptibility in UK Biobank brain imaging. Nature Neuroscience, 25(6), 818-831. https://doi.org/10.1038/s41593-022-01074-w

A key aim in epidemiological neuroscience is identification of markers to assess brain health and monitor therapeutic interventions. Quantitative susceptibility mapping (QSM) is an emerging magnetic resonance imaging technique that measures tissue ma... Read More about Phenotypic and genetic associations of quantitative magnetic susceptibility in UK Biobank brain imaging.

Bayesian causal network modeling suggests adolescent cannabis use accelerates prefrontal cortical thinning (2022)
Journal Article
Owens, M. M., Albaugh, M. D., Allgaier, N., Yuan, D., Robert, G., Cupertino, R. B., Spechler, P. A., Juliano, A., Hahn, S., Banaschewski, T., Bokde, A. L., Desrivières, S., Flor, H., Grigis, A., Gowland, P., Heinz, A., Brühl, R., Martinot, J. L., Martinot, M.-L. P., Artiges, E., …Hohmann, S. (2022). Bayesian causal network modeling suggests adolescent cannabis use accelerates prefrontal cortical thinning. Translational Psychiatry, 12(1), Article 188. https://doi.org/10.1038/s41398-022-01956-4

While there is substantial evidence that cannabis use is associated with differences in human brain development, most of this evidence is correlational in nature. Bayesian causal network (BCN) modeling attempts to identify probable causal relationshi... Read More about Bayesian causal network modeling suggests adolescent cannabis use accelerates prefrontal cortical thinning.

Pilot Double-Blind Randomised Controlled Trial: Effects of Jejunal Nutrition on Postprandial Distress in Diabetic Gastropathy (J4G Trial) (2022)
Journal Article
Carneiro, L., White, J., Parker, H., Hoad, C., Tucker, E., Marciani, L., Gowland, P., Gazis, T., Walker, M., & Fox, M. (2022). Pilot Double-Blind Randomised Controlled Trial: Effects of Jejunal Nutrition on Postprandial Distress in Diabetic Gastropathy (J4G Trial). Nutrients, 14(7), Article 1321. https://doi.org/10.3390/nu14071321

Nausea, vomiting and abdominal pain in diabetic patients are often attributed to diabetic gastropathy (DG). Post-pyloric (“jejunal”) enteral nutrition (JN) may improve nutrition and glycaemia in difficult cases. The acute effects of JN on postprandia... Read More about Pilot Double-Blind Randomised Controlled Trial: Effects of Jejunal Nutrition on Postprandial Distress in Diabetic Gastropathy (J4G Trial).

Brain structural covariance network differences in adults with alcohol dependence and heavy-drinking adolescents (2021)
Journal Article
Ottino-González, J., Albaugh, M. D., Cao, Z., Cupertino, R. B., Schwab, N., Spechler, P. A., Allen, N., Artiges, E., Banaschewski, T., Bokde, A. L. W., Burke Quinlan, E., Brühl, R., Orr, C., Cousijn, J., Desrivières, S., Flor, H., Foxe, J. J., Fröhner, J. H., Goudriaan, A. E., Gowland, P., …Garavan, H. (2022). Brain structural covariance network differences in adults with alcohol dependence and heavy-drinking adolescents. Addiction, 117(5), 1312-1325. https://doi.org/10.1111/add.15772

BACKGROUND AND AIMS: Graph theoretic analysis of structural covariance networks (SCN) provides an assessment of brain organization that has not yet been applied to alcohol dependence (AD). We estimated whether SCN differences are present in adults wi... Read More about Brain structural covariance network differences in adults with alcohol dependence and heavy-drinking adolescents.

The Human Connectome Project: A retrospective (2021)
Journal Article
Elam, J. S., Glasser, M. F., Harms, M. P., Sotiropoulos, S. N., Andersson, J. L., Burgess, G. C., Curtiss, S. W., Oostenveld, R., Larson-Prior, L. J., Schoffelen, J. M., Hodge, M. R., Cler, E. A., Marcus, D. M., Barch, D. M., Yacoub, E., Smith, S. M., Ugurbil, K., & Van Essen, D. C. (2021). The Human Connectome Project: A retrospective. NeuroImage, 244, Article 118543. https://doi.org/10.1016/j.neuroimage.2021.118543

The Human Connectome Project (HCP) was launched in 2010 as an ambitious effort to accelerate advances in human neuroimaging, particularly for measures of brain connectivity; apply these advances to study a large number of healthy young adults; and fr... Read More about The Human Connectome Project: A retrospective.

Predicting Depression Onset in Young People Based on Clinical, Cognitive, Environmental, and Neurobiological Data (2021)
Journal Article
Toenders, Y. J., Kottaram, A., Dinga, R., Davey, C. G., Banaschewski, T., Bokde, A. L., Quinlan, E. B., Desrivières, S., Flor, H., Grigis, A., Garavan, H., Gowland, P., Heinz, A., Brühl, R., Martinot, J.-L., Paillère Martinot, M.-L., Nees, F., Orfanos, D. P., Lemaitre, H., Paus, T., …Schmaal, L. (2022). Predicting Depression Onset in Young People Based on Clinical, Cognitive, Environmental, and Neurobiological Data. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, 7(4), 376-384. https://doi.org/10.1016/j.bpsc.2021.03.005

Background
Adolescent onset of depression is associated with long-lasting negative consequences. Identifying adolescents at risk for developing depression would enable the monitoring of risk-factors and the development of early intervention strategi... Read More about Predicting Depression Onset in Young People Based on Clinical, Cognitive, Environmental, and Neurobiological Data.

A data-driven approach to optimising the encoding for multi-shell diffusion MRI with application to neonatal imaging (2020)
Journal Article
Tournier, J.-D., Christiaens, D., Hutter, J., Price, A. N., Cordero-Grande, L., Hughes, E., Bastiani, M., Sotiropoulos, S. N., Smith, S. M., Rueckert, D., Counsell, S. J., Edwards, A. D., & Hajnal, J. V. (2020). A data-driven approach to optimising the encoding for multi-shell diffusion MRI with application to neonatal imaging. NMR in Biomedicine, 33(9), Article e4348. https://doi.org/10.1101/661348

Diffusion MRI has the potential to provide important information about the connectivity and microstructure of the human brain during normal and abnormal development, non-invasively and in vivo. Recent developments in MRI hardware and reconstruction m... Read More about A data-driven approach to optimising the encoding for multi-shell diffusion MRI with application to neonatal imaging.

XTRACT - Standardised protocols for automated tractography in the human and macaque brain (2020)
Journal Article
Warrington, S., Bryant, K. L., Khrapitchev, A. A., Sallet, J., Charquero-Ballester, M., Douaud, G., Jbabdi, S., Mars, R. B., & Sotiropoulos, S. N. (2020). XTRACT - Standardised protocols for automated tractography in the human and macaque brain. NeuroImage, 217, Article 116923. https://doi.org/10.1016/j.neuroimage.2020.116923

We present a new software package with a library of standardised tractography protocols devised for the robust automated extraction of white matter tracts both in the human and the macaque brain. Using in vivo data from the Human Connectome Project (... Read More about XTRACT - Standardised protocols for automated tractography in the human and macaque brain.

Mechanisms and Risk Factors Contributing to Visual Field Deficits following Stereotactic Laser Amygdalohippocampotomy (2019)
Journal Article
Voets, N. L., Alvarez, I., Qiu, D., Leatherday, C., Willie, J. T., Sotiropoulos, S., Gleichgerrcht, E., Bonilha, L., Pedersen, N., Kadom, N., Saindane, A., Gross, R. E., & Drane, D. L. (2019). Mechanisms and Risk Factors Contributing to Visual Field Deficits following Stereotactic Laser Amygdalohippocampotomy. Stereotactic and Functional Neurosurgery, 97(4), 255–265. https://doi.org/10.1159/000502701

Selective laser amygdalohippocampotomy (SLAH) is a minimally invasive surgical treatment for medial temporal lobe epilepsy. Visual field deficits (VFDs) are a significant potential complication. The objective of this study was to determine the relati... Read More about Mechanisms and Risk Factors Contributing to Visual Field Deficits following Stereotactic Laser Amygdalohippocampotomy.

Joint modelling of diffusion MRI and microscopy (2019)
Journal Article
Howard, A. F., Mollink, J., Kleinnijenhuis, M., Pallebage-Gamarallage, M., Bastiani, M., Cottaar, M., Miller, K. L., & Jbabdi, S. (2019). Joint modelling of diffusion MRI and microscopy. NeuroImage, 201, Article 116014. https://doi.org/10.1016/j.neuroimage.2019.116014

The combination of diffusion MRI (dMRI) with microscopy provides unique opportunities to study microstructural features of tissue, particularly when acquired in the same sample. Microscopy is frequently used to validate dMRI microstructure models, ad... Read More about Joint modelling of diffusion MRI and microscopy.

MRI of the colon in the pharmaceutical field: the future before us (2019)
Journal Article
Sulaiman, S., & Marciani, L. (2019). MRI of the colon in the pharmaceutical field: the future before us. Pharmaceutics, 11(4), Article 146. https://doi.org/10.3390/pharmaceutics11040146

Oral solid drug formulation is the most common route for administration and it is vital to increase knowledge of the gastrointestinal physiological environment to understand dissolution and absorption processes and to develop reliable biorelevant in... Read More about MRI of the colon in the pharmaceutical field: the future before us.

Hierarchical heterogeneity across human cortex shapes large-scale neural dynamics (2019)
Journal Article
Demirtas, M., Burt, J. B., Helmer, M., Ji, J. L., Adkinson, B. D., Glasser, M. F., Van Essen, D. C., Sotiropoulos, S. N., Anticevic, A., & Murray, J. D. (2019). Hierarchical heterogeneity across human cortex shapes large-scale neural dynamics. Neuron, 101(6), 1181-1194.e13. https://doi.org/10.1016/j.neuron.2019.01.017

The large-scale organization of dynamical neural activity across cortex emerges through long-range interactions among local circuits. We hypothesized that large-scale dynamics are also shaped by heterogeneity of intrinsic local properties across cort... Read More about Hierarchical heterogeneity across human cortex shapes large-scale neural dynamics.

Using GPUs to accelerate computational diffusion MRI: from microstructure estimation to tractography and connectomes (2018)
Journal Article
Hernandez-Fernandez, M., Reguly, I., Jbabdi, S., Giles, M., Smith, S., & Sotiropoulos, S. N. (2019). Using GPUs to accelerate computational diffusion MRI: from microstructure estimation to tractography and connectomes. NeuroImage, 188, 598-615. https://doi.org/10.1016/j.neuroimage.2018.12.015

The great potential of computational diffusion MRI (dMRI) relies on indirect inference of tissue microstructure and brain connections, since modelling and tractography frameworks map diffusion measurements to neuroanatomical features. This mapping ho... Read More about Using GPUs to accelerate computational diffusion MRI: from microstructure estimation to tractography and connectomes.

Automated quality control for within and between studies diffusion MRI data using a non-parametric framework for movement and distortion correction (2018)
Journal Article
Bastiani, M., Cottaar, M., Fitzgibbon, S. P., Suri, S., Alfaro-Almagro, F., Sotiropoulos, S. N., Jbabdi, S., & Andersson, J. (2019). Automated quality control for within and between studies diffusion MRI data using a non-parametric framework for movement and distortion correction. NeuroImage, 184, 801-812. https://doi.org/10.1016/j.neuroimage.2018.09.073

Diffusion MRI data can be affected by hardware and subject-related artefacts that can adversely affect downstream analyses. Therefore, automated quality control (QC) is of great importance, especially in large population studies where visual QC is no... Read More about Automated quality control for within and between studies diffusion MRI data using a non-parametric framework for movement and distortion correction.

Extending the Human Connectome Project across ages: imaging protocols for the Lifespan Development and Aging projects (2018)
Journal Article
Harms, M. P., Somerville, L. H., Ances, B. M., Andersson, J., Barch, D. M., Bastiani, M., Bookheimer, S. Y., Brown, T. B., Buckner, R. L., Burgess, G. C., Coalson, T. S., Chappell, M. A., Dapretto, M., Douaud, G., Fischl, B., Glasser, M. F., Greve, D. N., Hodge, C., Jamison, K. W., Jbabdi, S., …Yacoub, E. (2018). Extending the Human Connectome Project across ages: imaging protocols for the Lifespan Development and Aging projects. NeuroImage, 183, 972-984. https://doi.org/10.1016/j.neuroimage.2018.09.060

The Human Connectome Projects in Development (HCP-D) and Aging (HCP-A) are two large-scale brain imaging studies that will extend the recently completed HCP Young-Adult
(HCP-YA) project to nearly the full lifespan, collecting structural, resting-sta... Read More about Extending the Human Connectome Project across ages: imaging protocols for the Lifespan Development and Aging projects.

Cine MRI assessment of motility in the unprepared small bowel in the fasting and fed state: beyond the breath-hold (2018)
Journal Article
Hoad, C., Marciani, L., Spiller, R., Gowland, P., & Moran, G. (2019). Cine MRI assessment of motility in the unprepared small bowel in the fasting and fed state: beyond the breath-hold. Neurogastroenterology and Motility, 31(1), e13466. https://doi.org/10.1111/nmo.13466

Background

The symptoms of functional bowel disorders are common in postprandial but investigations are generally undertaken in the fasted state using invasive procedures. MRI provides a noninvasive tool to study the gastrointestinal tract in an u... Read More about Cine MRI assessment of motility in the unprepared small bowel in the fasting and fed state: beyond the breath-hold.

Cognitive neuroscience using wearable magnetometer arrays: Non-invasive assessment of language function (2018)
Journal Article
Tierney, T. M., Holmes, N., Meyer, S. S., Boto, E., Roberts, G., Leggett, J., Buck, S., Duque-Muñoz, L., Litvak, V., Bestmann, S., Baldeweg, T., Bowtell, R. W., Brookes, M. J., & Barnes, G. R. (2018). Cognitive neuroscience using wearable magnetometer arrays: Non-invasive assessment of language function. NeuroImage, 181, 513-520. https://doi.org/10.1016/j.neuroimage.2018.07.035

Recent work has demonstrated that Optically Pumped Magnetometers (OPMs) can be utilised to create a wearable Magnetoencephalography (MEG) system that is motion robust. In this study, we use this system to map eloquent cortex using a clinically valida... Read More about Cognitive neuroscience using wearable magnetometer arrays: Non-invasive assessment of language function.