All Outputs (2)

Global co-regulatory cross talk between m6A and m5C RNA methylation systems coordinate cellular responses and brain disease pathways (2024)
Journal Article
Orji, O. C., Stones, J., Rajani, S., Markus, R., Demirbugen Öz, M., & Knight, H. M. (2024). Global co-regulatory cross talk between m6A and m5C RNA methylation systems coordinate cellular responses and brain disease pathways. Molecular Neurobiology, https://doi.org/10.1007/s12035-024-04555-0

N6 adenosine and C5 cytosine modification of mRNAs, tRNAs and rRNAs are regulated by the behaviour of distinct sets of writer, reader and eraser effector proteins which are conventionally considered to function independently. Here, we provide evidenc... Read More about Global co-regulatory cross talk between m6A and m5C RNA methylation systems coordinate cellular responses and brain disease pathways.

Plasmodium NEK1 coordinates MTOC organisation and kinetochore attachment during rapid mitosis in male gamete formation (2024)
Journal Article
Zeeshan, M., Rashpa, R., Ferguson, D. J., Mckeown, G., Nugmanova, R., Subudhi, A. K., Beyeler, R., Pashley, S. L., Markus, R., Brady, D., Roques, M., Bottrill, A. R., Fry, A. M., Pain, A., Vaughan, S., Holder, A. A., Tromer, E. C., Brochet, M., & Tewari, R. (2024). Plasmodium NEK1 coordinates MTOC organisation and kinetochore attachment during rapid mitosis in male gamete formation. PLoS Biology, 22(9), Article e3002802. https://doi.org/10.1371/journal.pbio.3002802

Mitosis is an important process in the cell cycle required for cells to divide. Never in mitosis (NIMA)-like kinases (NEKs) are regulators of mitotic functions in diverse organisms. Plasmodium spp., the causative agent of malaria is a divergent unice... Read More about Plasmodium NEK1 coordinates MTOC organisation and kinetochore attachment during rapid mitosis in male gamete formation.