Blood platelets stimulate cancer extravasation through TGFβ-mediated downregulation of PRH/HHEX
(2020)
Journal Article
Marcolino De Assis, E., Siddiqui, Y. H., van den Bosch, M., Poole, A. W., Jayaraman, P., & Gaston, K. (2020). Blood platelets stimulate cancer extravasation through TGFβ-mediated downregulation of PRH/HHEX. Oncogenesis, 9, Article 10. https://doi.org/10.1038/s41389-020-0189-0
Cancer cells go through a process known as epithelial–mesenchymal transition (EMT) during which they acquire the ability to migrate and invade extracellular matrix. Some cells also acquire the ability to move across a layer of endothelial cells to en... Read More about Blood platelets stimulate cancer extravasation through TGFβ-mediated downregulation of PRH/HHEX.